Sec61β maintains cytoplasmic proteostasis via ARIH1-mediated translational repression upon ER stress. - Kadowaki H; Hatta T; Sugiyama K; Fukaya T; Fujisawa T; Hamano T; Murao N; Takami Y; Mitoma S; Natsume T; Sato K; Hirata H; et al. (EMBO reports, 2026)