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Development and validation of a neural network survival prediction model for ischemic heart disease.

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Title: Development and validation of a neural network survival prediction model for ischemic heart disease.
Authors: Holm PC; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark., Haue AD; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Department of Cardiology, The Heart Center, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark., Westergaard D; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Department Obstetrics and Gynecology, Copenhagen University Hospital, Kettegård Alle 30, 2650, Hvidovre, Denmark.; Methods and Analysis, Statistics Denmark, Sejrøgade 11, 2100, Copenhagen, Denmark., Röder T; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark., Banasik K; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Department Obstetrics and Gynecology, Copenhagen University Hospital, Kettegård Alle 30, 2650, Hvidovre, Denmark., Tragante V; deCODE Genetics, Sturlugata 8, 102, Reykjavik, Iceland., Johansen CH; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark., Christensen AH; Department of Cardiology, The Heart Center, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Department of Cardiology, Copenhagen University Hospital, Herlev-Gentofte Hospital, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark., Thomas L; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, 7491, Trondheim, Norway.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, 7491, Trondheim, Norway., Nøst TH; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, 7491, Trondheim, Norway., Skogholt AH; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, 7491, Trondheim, Norway., Iversen KK; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Department of Cardiology, Copenhagen University Hospital, Herlev-Gentofte Hospital, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark., Pedersen F; Department of Cardiology, The Heart Center, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark., Høfsten DE; Department of Cardiology, The Heart Center, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark., Pedersen OB; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Department of Clinical Immunology, Zealand University Hospital, 4600, Køge, Denmark., Ostrowski SR; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark., Ullum H; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.; Statens Serum Institut, Artillerivej 5, 2300, Copenhagen, Denmark., Svendsen MN; Department of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1353, Copenhagen, Denmark., Gjødsbøl IM; Department of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1353, Copenhagen, Denmark., Gudnason T; Laeknasetrid Cardiology Clinic, Thonglabakka 1, 109, Reykjavík, Iceland., Guðbjartsson DF; deCODE Genetics, Sturlugata 8, 102, Reykjavik, Iceland., Helgadottir A; deCODE Genetics, Sturlugata 8, 102, Reykjavik, Iceland., Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, 7491, Trondheim, Norway., Køber LV; Department of Cardiology, The Heart Center, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark., Holm H; deCODE Genetics, Sturlugata 8, 102, Reykjavik, Iceland., Stefansson K; deCODE Genetics, Sturlugata 8, 102, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, Reykjavik, 101, Iceland., Brunak S; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark. soren.brunak@cpr.ku.dk.; Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark. soren.brunak@cpr.ku.dk., Bundgaard H; Department of Cardiology, The Heart Center, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.
Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2026 Jan 28; Vol. 25 (1), pp. 59. Date of Electronic Publication: 2026 Jan 28.
Publication Type: Journal Article; Validation Study
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2840 (Electronic) Linking ISSN: 14752840 NLM ISO Abbreviation: Cardiovasc Diabetol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Holm+PC%22">Holm PC</searchLink>; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Haue+AD%22">Haue AD</searchLink>; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Department of Cardiology, The Heart Center, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Westergaard+D%22">Westergaard D</searchLink>; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Department Obstetrics and Gynecology, Copenhagen University Hospital, Kettegård Alle 30, 2650, Hvidovre, Denmark.; Methods and Analysis, Statistics Denmark, Sejrøgade 11, 2100, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Röder+T%22">Röder T</searchLink>; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Banasik+K%22">Banasik K</searchLink>; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Department Obstetrics and Gynecology, Copenhagen University Hospital, Kettegård Alle 30, 2650, Hvidovre, Denmark.<br /><searchLink fieldCode="AU" term="%22Tragante+V%22">Tragante V</searchLink>; deCODE Genetics, Sturlugata 8, 102, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Johansen+CH%22">Johansen CH</searchLink>; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Christensen+AH%22">Christensen AH</searchLink>; Department of Cardiology, The Heart Center, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Department of Cardiology, Copenhagen University Hospital, Herlev-Gentofte Hospital, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Thomas+L%22">Thomas L</searchLink>; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, 7491, Trondheim, Norway.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, 7491, Trondheim, Norway.<br /><searchLink fieldCode="AU" term="%22Nøst+TH%22">Nøst TH</searchLink>; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, 7491, Trondheim, Norway.<br /><searchLink fieldCode="AU" term="%22Skogholt+AH%22">Skogholt AH</searchLink>; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, 7491, Trondheim, Norway.<br /><searchLink fieldCode="AU" term="%22Iversen+KK%22">Iversen KK</searchLink>; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Department of Cardiology, Copenhagen University Hospital, Herlev-Gentofte Hospital, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Pedersen+F%22">Pedersen F</searchLink>; Department of Cardiology, The Heart Center, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Høfsten+DE%22">Høfsten DE</searchLink>; Department of Cardiology, The Heart Center, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Pedersen+OB%22">Pedersen OB</searchLink>; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Department of Clinical Immunology, Zealand University Hospital, 4600, Køge, Denmark.<br /><searchLink fieldCode="AU" term="%22Ostrowski+SR%22">Ostrowski SR</searchLink>; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Ullum+H%22">Ullum H</searchLink>; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.; Statens Serum Institut, Artillerivej 5, 2300, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Svendsen+MN%22">Svendsen MN</searchLink>; Department of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1353, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Gjødsbøl+IM%22">Gjødsbøl IM</searchLink>; Department of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1353, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Gudnason+T%22">Gudnason T</searchLink>; Laeknasetrid Cardiology Clinic, Thonglabakka 1, 109, Reykjavík, Iceland.<br /><searchLink fieldCode="AU" term="%22Guðbjartsson+DF%22">Guðbjartsson DF</searchLink>; deCODE Genetics, Sturlugata 8, 102, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Helgadottir+A%22">Helgadottir A</searchLink>; deCODE Genetics, Sturlugata 8, 102, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Hveem+K%22">Hveem K</searchLink>; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, 7491, Trondheim, Norway.<br /><searchLink fieldCode="AU" term="%22Køber+LV%22">Køber LV</searchLink>; Department of Cardiology, The Heart Center, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Holm+H%22">Holm H</searchLink>; deCODE Genetics, Sturlugata 8, 102, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Stefansson+K%22">Stefansson K</searchLink>; deCODE Genetics, Sturlugata 8, 102, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, Reykjavik, 101, Iceland.<br /><searchLink fieldCode="AU" term="%22Brunak+S%22">Brunak S</searchLink>; Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark. soren.brunak@cpr.ku.dk.; Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark. soren.brunak@cpr.ku.dk.<br /><searchLink fieldCode="AU" term="%22Bundgaard+H%22">Bundgaard H</searchLink>; Department of Cardiology, The Heart Center, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.
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