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Ensuring long-term arrhythmia freedom: what are the options for long-standing persistent atrial fibrillation?

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Title: Ensuring long-term arrhythmia freedom: what are the options for long-standing persistent atrial fibrillation?
Authors: Kotoulas SC; 1st Department of Cardiology, 'Hippokration' General Hospital, National and Kapodistrian University of Athens, Athens, Greece.; Cardiology Clinic, General Hospital Asklepeion Voulas, Athens, Greece., Doundoulakis I; 1st Department of Cardiology, 'Hippokration' General Hospital, National and Kapodistrian University of Athens, Athens, Greece.; Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Brussels, Belgium., Tsiachris D; 1st Department of Cardiology, 'Hippokration' General Hospital, National and Kapodistrian University of Athens, Athens, Greece., Pannone L; Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Brussels, Belgium., Botis M; 1st Department of Cardiology, 'Hippokration' General Hospital, National and Kapodistrian University of Athens, Athens, Greece., Poulimenos LS; Cardiology Clinic, General Hospital Asklepeion Voulas, Athens, Greece., Chiotis S; 'Hippokration' General Hospital, Third University Department of Cardiology, Aristotle University of Thessaloniki, Thessaloniki, Greece., Kordalis A; 1st Department of Cardiology, 'Hippokration' General Hospital, National and Kapodistrian University of Athens, Athens, Greece., Chierchia GB; Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Brussels, Belgium., de Asmundis C; Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Brussels, Belgium., Tsioufis C; 1st Department of Cardiology, 'Hippokration' General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Source: Expert review of cardiovascular therapy [Expert Rev Cardiovasc Ther] 2026 Jan-Feb; Vol. 24 (2), pp. 93-106. Date of Electronic Publication: 2026 Jan 28.
Publication Type: Journal Article; Review
Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101182328 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-8344 (Electronic) Linking ISSN: 14779072 NLM ISO Abbreviation: Expert Rev Cardiovasc Ther Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Kotoulas+SC%22">Kotoulas SC</searchLink>; 1st Department of Cardiology, 'Hippokration' General Hospital, National and Kapodistrian University of Athens, Athens, Greece.; Cardiology Clinic, General Hospital Asklepeion Voulas, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Doundoulakis+I%22">Doundoulakis I</searchLink>; 1st Department of Cardiology, 'Hippokration' General Hospital, National and Kapodistrian University of Athens, Athens, Greece.; Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Tsiachris+D%22">Tsiachris D</searchLink>; 1st Department of Cardiology, 'Hippokration' General Hospital, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Pannone+L%22">Pannone L</searchLink>; Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Botis+M%22">Botis M</searchLink>; 1st Department of Cardiology, 'Hippokration' General Hospital, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Poulimenos+LS%22">Poulimenos LS</searchLink>; Cardiology Clinic, General Hospital Asklepeion Voulas, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Chiotis+S%22">Chiotis S</searchLink>; 'Hippokration' General Hospital, Third University Department of Cardiology, Aristotle University of Thessaloniki, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Kordalis+A%22">Kordalis A</searchLink>; 1st Department of Cardiology, 'Hippokration' General Hospital, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Chierchia+GB%22">Chierchia GB</searchLink>; Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22de+Asmundis+C%22">de Asmundis C</searchLink>; Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Tsioufis+C%22">Tsioufis C</searchLink>; 1st Department of Cardiology, 'Hippokration' General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
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