Deep learning-based plaque characterization in hybrid IVUS-OCT images is superior to single-modality deep learning analysis and human experts: head-to-head comparison against histology.

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Title: Deep learning-based plaque characterization in hybrid IVUS-OCT images is superior to single-modality deep learning analysis and human experts: head-to-head comparison against histology.
Authors: Bajaj R; Department of Cardiology, St Michael's Hospital, Toronto, Canada.; Division of Cardiology, University of Toronto, Toronto, Canada.; Cardiovascular Devices Hub, Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, Queen Mary University of London, London, UK., Huang X; School of Electronic Engineering and Computer Science, Queen Mary University of London, London, UK., Alves-Kotzev N; Sunnybrook Health Sciences Centre, Toronto, Canada., Weyers JJ; Sunnybrook Health Sciences Centre, Toronto, Canada., Levine M; Department of Cardiology, Medstar Cardiovascular Research Network, Medstar Washington Hospital Center, Washington, DC, USA., Garg M; Department of Cardiology, Medstar Cardiovascular Research Network, Medstar Washington Hospital Center, Washington, DC, USA., Mohamed M; Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, West Smithfield, London EC1A 7BE, UK., Maung S; Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, West Smithfield, London EC1A 7BE, UK., Parasa R; Cardiovascular Devices Hub, Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, Queen Mary University of London, London, UK.; Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, West Smithfield, London EC1A 7BE, UK., Çap M; Department of Cardiology, University of Health Sciences, Diyarbakir Gazi Yasargil Education and Research Hospital, Diyarbakir, Turkey., Torii R; Department of Mechanical Engineering, University College London, London, UK., Krams R; School of Electronic Engineering and Computer Science, Queen Mary University of London, London, UK., Butany J; Laboratory Medicine and Pathobiology, University of Toronto., Biccirè FG; Department of Cardiology, Bern University Hospital, Bern, Switzerland., Garcia-Garcia H; Department of Cardiology, Medstar Cardiovascular Research Network, Medstar Washington Hospital Center, Washington, DC, USA., Raber L; Department of Cardiology, Bern University Hospital, Bern, Switzerland., Mathur A; Cardiovascular Devices Hub, Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, Queen Mary University of London, London, UK.; Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, West Smithfield, London EC1A 7BE, UK., Baumbach A; Cardiovascular Devices Hub, Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, Queen Mary University of London, London, UK.; Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, West Smithfield, London EC1A 7BE, UK., Zhang Q; School of Electronic Engineering and Computer Science, Queen Mary University of London, London, UK., Courtney BK; Sunnybrook Health Sciences Centre, Toronto, Canada., Bourantas CV; Cardiovascular Devices Hub, Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, Queen Mary University of London, London, UK.; Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, West Smithfield, London EC1A 7BE, UK.
Source: Cardiovascular research [Cardiovasc Res] 2026 Mar 16; Vol. 122 (2), pp. 245-257.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245 (Electronic) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Deep learning-based plaque characterization in hybrid IVUS-OCT images is superior to single-modality deep learning analysis and human experts: head-to-head comparison against histology.
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  Data: <searchLink fieldCode="AU" term="%22Bajaj+R%22">Bajaj R</searchLink>; Department of Cardiology, St Michael's Hospital, Toronto, Canada.; Division of Cardiology, University of Toronto, Toronto, Canada.; Cardiovascular Devices Hub, Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Huang+X%22">Huang X</searchLink>; School of Electronic Engineering and Computer Science, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Alves-Kotzev+N%22">Alves-Kotzev N</searchLink>; Sunnybrook Health Sciences Centre, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Weyers+JJ%22">Weyers JJ</searchLink>; Sunnybrook Health Sciences Centre, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Levine+M%22">Levine M</searchLink>; Department of Cardiology, Medstar Cardiovascular Research Network, Medstar Washington Hospital Center, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Garg+M%22">Garg M</searchLink>; Department of Cardiology, Medstar Cardiovascular Research Network, Medstar Washington Hospital Center, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Mohamed+M%22">Mohamed M</searchLink>; Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, West Smithfield, London EC1A 7BE, UK.<br /><searchLink fieldCode="AU" term="%22Maung+S%22">Maung S</searchLink>; Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, West Smithfield, London EC1A 7BE, UK.<br /><searchLink fieldCode="AU" term="%22Parasa+R%22">Parasa R</searchLink>; Cardiovascular Devices Hub, Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, Queen Mary University of London, London, UK.; Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, West Smithfield, London EC1A 7BE, UK.<br /><searchLink fieldCode="AU" term="%22Çap+M%22">Çap M</searchLink>; Department of Cardiology, University of Health Sciences, Diyarbakir Gazi Yasargil Education and Research Hospital, Diyarbakir, Turkey.<br /><searchLink fieldCode="AU" term="%22Torii+R%22">Torii R</searchLink>; Department of Mechanical Engineering, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Krams+R%22">Krams R</searchLink>; School of Electronic Engineering and Computer Science, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Butany+J%22">Butany J</searchLink>; Laboratory Medicine and Pathobiology, University of Toronto.<br /><searchLink fieldCode="AU" term="%22Biccirè+FG%22">Biccirè FG</searchLink>; Department of Cardiology, Bern University Hospital, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Garcia-Garcia+H%22">Garcia-Garcia H</searchLink>; Department of Cardiology, Medstar Cardiovascular Research Network, Medstar Washington Hospital Center, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Raber+L%22">Raber L</searchLink>; Department of Cardiology, Bern University Hospital, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mathur+A%22">Mathur A</searchLink>; Cardiovascular Devices Hub, Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, Queen Mary University of London, London, UK.; Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, West Smithfield, London EC1A 7BE, UK.<br /><searchLink fieldCode="AU" term="%22Baumbach+A%22">Baumbach A</searchLink>; Cardiovascular Devices Hub, Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, Queen Mary University of London, London, UK.; Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, West Smithfield, London EC1A 7BE, UK.<br /><searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; School of Electronic Engineering and Computer Science, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Courtney+BK%22">Courtney BK</searchLink>; Sunnybrook Health Sciences Centre, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Bourantas+CV%22">Bourantas CV</searchLink>; Cardiovascular Devices Hub, Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, Queen Mary University of London, London, UK.; Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, West Smithfield, London EC1A 7BE, UK.
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              Text: 2026 Mar 16
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