Clinical course and prognostic risk factors of SARS-CoV-2 vaccine-related hepatitis: differentiating severe acute respiratory syndrome coronavirus 2 vaccine-associated liver injury from autoimmune hepatitis.

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Title: Clinical course and prognostic risk factors of SARS-CoV-2 vaccine-related hepatitis: differentiating severe acute respiratory syndrome coronavirus 2 vaccine-associated liver injury from autoimmune hepatitis.
Authors: Malino D; Fondazione Epatocentro Ticino., Codoni G; Facoltà di Scienze Biomediche, Università della Svizzera Italiana, Lugano, Switzerland., Kirchner T; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER)., Engel B; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER)., Villamil AM; HIBA, Buenos Aires, Argentina., Efe C; Harran University, Şanliurfa, Turkey., Stättermayer AF; Medical University of Vienna, Wien, Austria., Weltzsch JP; European Reference Network on Hepatological Diseases (ERN RARE-LIVER).; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Sebode M; European Reference Network on Hepatological Diseases (ERN RARE-LIVER).; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Bernsmeier C; University Centre for Gastrointestinal and Liver Diseases, Basel, Switzerland., Lleo A; IRCCS Humanitas Research Hospital Milan & Humanitas University, Pieve Emanuele, Milan, Italy., Gevers TJG; European Reference Network on Hepatological Diseases (ERN RARE-LIVER).; Maastricht University Medical Center, Maastricht, The Netherlands., Kupčinskas L; European Reference Network on Hepatological Diseases (ERN RARE-LIVER).; Lithuanian University of Health Sciences, Kaunas, Lithuania., Castiella A; Donostia University Hospital, Donostia., Pinazo J; Servicios de Ap Digestivo y Farmacologia Clínica, Hospital Universitario Virgen de la Victoria, IBIMA Plataforma BIONAND, Universidad de Málaga, Malaga, Spain., De Martin E; Hépatologie et Transplantation Hépatique, Hôpital Paul Brousse, Villejuif, France., Bobis I; Städtisches Krankenhaus Kiel, Kiel, Germany., Sandahl TD; Aarhus University Hospital, Aarhus, Denmark., Pedica F; Ospedale San Raffaele, Milano., Invernizzi F; Policlinico San Marco, Zingonia, Italy., Del Poggio P; Policlinico San Marco, Zingonia, Italy., Bruns T; European Reference Network on Hepatological Diseases (ERN RARE-LIVER).; Departement of Medicine III, University Hospital RWTH Aachen, Aachen, Germany., Kolev M; Hepatology, University Clinic for Visceral Surgery and Medicine, Inselspital Bern, University of Bern, Bern, Switzerland., Semmo N; Hepatology, University Clinic for Visceral Surgery and Medicine, Inselspital Bern, University of Bern, Bern, Switzerland., Bessone F; University of Rosario School of Medicine, Rosario, Argentina., Giguet B; Centre Hospitalier Universitaire de Rennes, Rennes, France., Poggi G; Istituti Clinici Pavia-Vigevano UO Epatologia Oncologica, Vigevano, Italy., Ueno M; Department of Gastroenterology and Hepatology, Kurashiki Central Hospital, Kurashiki, Japan.; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto., Jang H; Department of Clinical Immunology and Allergy, Royal North Shore Hospital, St Leonards, Australia., Elpek GÖ; Department of Pathology, Akdeniz University Faculty of Medicine, Antalya., Soylu NK; Department of Pathology, Inonu University Faculty of Medicine, Malatya, Turkey., Cerny A; Fondazione Epatocentro Ticino., Wedemeyer H; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER)., Matter MS; University Hospital Basel, Institute of Medical Genetics and Pathology, Basel, Switzerland., Uzun S; University Hospital Basel, Institute of Medical Genetics and Pathology, Basel, Switzerland., Matilla-Cabello G; Servicios de Ap Digestivo y Farmacologia Clínica, Hospital Universitario Virgen de la Victoria, IBIMA Plataforma BIONAND, Universidad de Málaga, Malaga, Spain., Vergani D; MowatLabs, Faculty of Life Sciences & Medicine, King's College London, King's College Hospital, London, UK., Mieli-Vergani G; MowatLabs, Faculty of Life Sciences & Medicine, King's College London, King's College Hospital, London, UK., Lucena MI; Servicios de Ap Digestivo y Farmacologia Clínica, Hospital Universitario Virgen de la Victoria, IBIMA Plataforma BIONAND, Universidad de Málaga, Malaga, Spain.; Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain., Andrade RJ; Servicios de Ap Digestivo y Farmacologia Clínica, Hospital Universitario Virgen de la Victoria, IBIMA Plataforma BIONAND, Universidad de Málaga, Malaga, Spain.; Servizio di Gastroenterologia ed Epatologia, Ente Ospedaliero Cantonale, Ospedale Civico, Lugano, Switzerland., Zen Y; MowatLabs, Faculty of Life Sciences & Medicine, King's College London, King's College Hospital, London, UK., Taubert R; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER)., Terziroli Beretta-Piccoli B; Fondazione Epatocentro Ticino.; Facoltà di Scienze Biomediche, Università della Svizzera Italiana, Lugano, Switzerland.; MowatLabs, Faculty of Life Sciences & Medicine, King's College London, King's College Hospital, London, UK.; Servizio di Gastroenterologia ed Epatologia, Ente Ospedaliero Cantonale, Ospedale Civico, Lugano, Switzerland.
Source: European journal of gastroenterology & hepatology [Eur J Gastroenterol Hepatol] 2026 May 01; Vol. 38 (5), pp. 615-624. Date of Electronic Publication: 2026 Jan 29.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams And Wilkins Country of Publication: England NLM ID: 9000874 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-5687 (Electronic) Linking ISSN: 0954691X NLM ISO Abbreviation: Eur J Gastroenterol Hepatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Clinical course and prognostic risk factors of SARS-CoV-2 vaccine-related hepatitis: differentiating severe acute respiratory syndrome coronavirus 2 vaccine-associated liver injury from autoimmune hepatitis.
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  Data: <searchLink fieldCode="AU" term="%22Malino+D%22">Malino D</searchLink>; Fondazione Epatocentro Ticino.<br /><searchLink fieldCode="AU" term="%22Codoni+G%22">Codoni G</searchLink>; Facoltà di Scienze Biomediche, Università della Svizzera Italiana, Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kirchner+T%22">Kirchner T</searchLink>; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER).<br /><searchLink fieldCode="AU" term="%22Engel+B%22">Engel B</searchLink>; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER).<br /><searchLink fieldCode="AU" term="%22Villamil+AM%22">Villamil AM</searchLink>; HIBA, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Efe+C%22">Efe C</searchLink>; Harran University, Şanliurfa, Turkey.<br /><searchLink fieldCode="AU" term="%22Stättermayer+AF%22">Stättermayer AF</searchLink>; Medical University of Vienna, Wien, Austria.<br /><searchLink fieldCode="AU" term="%22Weltzsch+JP%22">Weltzsch JP</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER).; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Sebode+M%22">Sebode M</searchLink>; European Reference Network on Hepatological Diseases (ERN RARE-LIVER).; I. 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European Reference Network on Hepatological Diseases (ERN RARE-LIVER).; Departement of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Kolev+M%22">Kolev M</searchLink>; Hepatology, University Clinic for Visceral Surgery and Medicine, Inselspital Bern, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Semmo+N%22">Semmo N</searchLink>; Hepatology, University Clinic for Visceral Surgery and Medicine, Inselspital Bern, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bessone+F%22">Bessone F</searchLink>; University of Rosario School of Medicine, Rosario, Argentina.<br /><searchLink fieldCode="AU" term="%22Giguet+B%22">Giguet B</searchLink>; Centre Hospitalier Universitaire de Rennes, Rennes, France.<br /><searchLink fieldCode="AU" term="%22Poggi+G%22">Poggi G</searchLink>; Istituti Clinici Pavia-Vigevano UO Epatologia Oncologica, Vigevano, Italy.<br /><searchLink fieldCode="AU" term="%22Ueno+M%22">Ueno M</searchLink>; 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Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas (CIBERehd), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Andrade+RJ%22">Andrade RJ</searchLink>; Servicios de Ap Digestivo y Farmacologia Clínica, Hospital Universitario Virgen de la Victoria, IBIMA Plataforma BIONAND, Universidad de Málaga, Malaga, Spain.; Servizio di Gastroenterologia ed Epatologia, Ente Ospedaliero Cantonale, Ospedale Civico, Lugano, Switzerland.<br /><searchLink fieldCode="AU" term="%22Zen+Y%22">Zen Y</searchLink>; MowatLabs, Faculty of Life Sciences & Medicine, King's College London, King's College Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Taubert+R%22">Taubert R</searchLink>; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany.; European Reference Network on Hepatological Diseases (ERN RARE-LIVER).<br /><searchLink fieldCode="AU" term="%22Terziroli+Beretta-Piccoli+B%22">Terziroli Beretta-Piccoli B</searchLink>; Fondazione Epatocentro Ticino.; Facoltà di Scienze Biomediche, Università della Svizzera Italiana, Lugano, Switzerland.; MowatLabs, Faculty of Life Sciences & Medicine, King's College London, King's College Hospital, London, UK.; Servizio di Gastroenterologia ed Epatologia, Ente Ospedaliero Cantonale, Ospedale Civico, Lugano, Switzerland.
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