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Progressive Changes in Brain Morphology in People With Idiopathic Generalized Epilepsy.

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Title: Progressive Changes in Brain Morphology in People With Idiopathic Generalized Epilepsy.
Authors: Xiao F; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom., Zhang Y; Department of Neurology, West China Hospital, Sichuan University, Chengdu, China., Wandschneider B; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom., Binding LP; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.; Centre for Medical Image Computing, UCL Departments of Computer Science, Medical Physics, and Biomedical Engineering, London, United Kingdom., Giampiccolo D; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.; Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, United Kingdom., Fleury M; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom., Delazer L; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.; Department of Neurology, Medical University of Innsbruck, Austria., Pimentel BC; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.; Department of Neurology, Neurointensive Care and Neurorehabilitation, Christian Doppler University Hospital, Paracelsus Medical University, Centre for Cognitive Neuroscience Salzburg, Austria., Puntambekar I; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom., Fukuma K; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom., Caciagli L; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.; Department of Neurology, Inselspital, Sleep-Wake-Epilepsy-Center, Bern University Hospital, University of Bern, Switzerland; and., Sander JW; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.; Department of Neurology, West China Hospital, Sichuan University, Chengdu, China.; Centre for Global Epilepsy, Wolfson College, Oxford, United Kingdom., Duncan JS; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom., Zhou D; Department of Neurology, West China Hospital, Sichuan University, Chengdu, China., Koepp MJ; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.
Source: Neurology [Neurology] 2026 Feb 24; Vol. 106 (4), pp. e214647. Date of Electronic Publication: 2026 Jan 28.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0401060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-632X (Electronic) Linking ISSN: 00283878 NLM ISO Abbreviation: Neurology Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Xiao+F%22">Xiao F</searchLink>; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Neurology, West China Hospital, Sichuan University, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Wandschneider+B%22">Wandschneider B</searchLink>; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Binding+LP%22">Binding LP</searchLink>; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.; Centre for Medical Image Computing, UCL Departments of Computer Science, Medical Physics, and Biomedical Engineering, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Giampiccolo+D%22">Giampiccolo D</searchLink>; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.; Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Fleury+M%22">Fleury M</searchLink>; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Delazer+L%22">Delazer L</searchLink>; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.; Department of Neurology, Medical University of Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Pimentel+BC%22">Pimentel BC</searchLink>; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.; Department of Neurology, Neurointensive Care and Neurorehabilitation, Christian Doppler University Hospital, Paracelsus Medical University, Centre for Cognitive Neuroscience Salzburg, Austria.<br /><searchLink fieldCode="AU" term="%22Puntambekar+I%22">Puntambekar I</searchLink>; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Fukuma+K%22">Fukuma K</searchLink>; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Caciagli+L%22">Caciagli L</searchLink>; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.; Department of Neurology, Inselspital, Sleep-Wake-Epilepsy-Center, Bern University Hospital, University of Bern, Switzerland; and.<br /><searchLink fieldCode="AU" term="%22Sander+JW%22">Sander JW</searchLink>; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.; Department of Neurology, West China Hospital, Sichuan University, Chengdu, China.; Centre for Global Epilepsy, Wolfson College, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Duncan+JS%22">Duncan JS</searchLink>; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Zhou+D%22">Zhou D</searchLink>; Department of Neurology, West China Hospital, Sichuan University, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Koepp+MJ%22">Koepp MJ</searchLink>; Department of Clinical & Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Chalfont St Peter, United Kingdom.
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