PAF15-PCNA exhaustion governs the strand-specific control of DNA replication.
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| Title: | PAF15-PCNA exhaustion governs the strand-specific control of DNA replication. |
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| Authors: | Chhetri G; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Badugu SB; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Petriman NA; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Petersen MB; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Güller AS; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Fajri N; Genome Integrity and Cancers, Gustave Roussy, Université Paris-Saclay, CNRS, Villejuif, France., Coulée M; Genome Integrity and Cancers, Gustave Roussy, Université Paris-Saclay, CNRS, Villejuif, France., Pitchai GP; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Novotný J; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Larsen FT; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.; Center for Functional Genomics and Tissue Plasticity (ATLAS), University of Southern Denmark, Odense, Denmark., Møller AF; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.; Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, USA., Ebbesen MF; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Ravnsborg T; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Yadav AK; Institute of Biophysics of the Czech Academy of Sciences, Brno, Czech Republic.; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic., Balarasa B; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Lunding A; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Polasek-Sedlackova H; Institute of Biophysics of the Czech Academy of Sciences, Brno, Czech Republic., Jensen ON; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Ravnskjaer K; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.; Center for Functional Genomics and Tissue Plasticity (ATLAS), University of Southern Denmark, Odense, Denmark., Brewer JR; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.; Center for Functional Genomics and Tissue Plasticity (ATLAS), University of Southern Denmark, Odense, Denmark., Madsen JGS; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.; Center for Functional Genomics and Tissue Plasticity (ATLAS), University of Southern Denmark, Odense, Denmark.; Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, USA., Petryk N; Genome Integrity and Cancers, Gustave Roussy, Université Paris-Saclay, CNRS, Villejuif, France., Andersen JS; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark., Somyajit K; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark. ksom@sdu.dk. |
| Source: | Nature [Nature] 2026 Mar; Vol. 651 (8105), pp. 521-532. Date of Electronic Publication: 2026 Jan 28. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41606318 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: PAF15-PCNA exhaustion governs the strand-specific control of DNA replication. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Chhetri+G%22">Chhetri G</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Badugu+SB%22">Badugu SB</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Petriman+NA%22">Petriman NA</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Petersen+MB%22">Petersen MB</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Güller+AS%22">Güller AS</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Fajri+N%22">Fajri N</searchLink>; Genome Integrity and Cancers, Gustave Roussy, Université Paris-Saclay, CNRS, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Coulée+M%22">Coulée M</searchLink>; Genome Integrity and Cancers, Gustave Roussy, Université Paris-Saclay, CNRS, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Pitchai+GP%22">Pitchai GP</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Novotný+J%22">Novotný J</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Larsen+FT%22">Larsen FT</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.; Center for Functional Genomics and Tissue Plasticity (ATLAS), University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Møller+AF%22">Møller AF</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.; Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, USA.<br /><searchLink fieldCode="AU" term="%22Ebbesen+MF%22">Ebbesen MF</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Ravnsborg+T%22">Ravnsborg T</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Yadav+AK%22">Yadav AK</searchLink>; Institute of Biophysics of the Czech Academy of Sciences, Brno, Czech Republic.; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Balarasa+B%22">Balarasa B</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Lunding+A%22">Lunding A</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Polasek-Sedlackova+H%22">Polasek-Sedlackova H</searchLink>; Institute of Biophysics of the Czech Academy of Sciences, Brno, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Jensen+ON%22">Jensen ON</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Ravnskjaer+K%22">Ravnskjaer K</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.; Center for Functional Genomics and Tissue Plasticity (ATLAS), University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Brewer+JR%22">Brewer JR</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.; Center for Functional Genomics and Tissue Plasticity (ATLAS), University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Madsen+JGS%22">Madsen JGS</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.; Center for Functional Genomics and Tissue Plasticity (ATLAS), University of Southern Denmark, Odense, Denmark.; Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, USA.<br /><searchLink fieldCode="AU" term="%22Petryk+N%22">Petryk N</searchLink>; Genome Integrity and Cancers, Gustave Roussy, Université Paris-Saclay, CNRS, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Andersen+JS%22">Andersen JS</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Somyajit+K%22">Somyajit K</searchLink>; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark. ksom@sdu.dk. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2026 Mar; Vol. 651 (8105), pp. 521-532. <i>Date of Electronic Publication: </i>2026 Jan 28. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0410462 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-4687 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200280836%22">00280836 </searchLink><i>NLM ISO Abbreviation: </i>Nature <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41606318 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41586-025-10011-3 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 521 Titles: – TitleFull: PAF15-PCNA exhaustion governs the strand-specific control of DNA replication. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Chhetri G – PersonEntity: Name: NameFull: Badugu SB – PersonEntity: Name: NameFull: Petriman NA – PersonEntity: Name: NameFull: Petersen MB – PersonEntity: Name: NameFull: Güller AS – PersonEntity: Name: NameFull: Fajri N – PersonEntity: Name: NameFull: Coulée M – PersonEntity: Name: NameFull: Pitchai GP – PersonEntity: Name: NameFull: Novotný J – PersonEntity: Name: NameFull: Larsen FT – PersonEntity: Name: NameFull: Møller AF – PersonEntity: Name: NameFull: Ebbesen MF – PersonEntity: Name: NameFull: Ravnsborg T – PersonEntity: Name: NameFull: Yadav AK – PersonEntity: Name: NameFull: Balarasa B – PersonEntity: Name: NameFull: Lunding A – PersonEntity: Name: NameFull: Polasek-Sedlackova H – PersonEntity: Name: NameFull: Jensen ON – PersonEntity: Name: NameFull: Ravnskjaer K – PersonEntity: Name: NameFull: Brewer JR – PersonEntity: Name: NameFull: Madsen JGS – PersonEntity: Name: NameFull: Petryk N – PersonEntity: Name: NameFull: Andersen JS – PersonEntity: Name: NameFull: Somyajit K IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: 2026 Mar Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1476-4687 Numbering: – Type: volume Value: 651 – Type: issue Value: 8105 Titles: – TitleFull: Nature Type: main |
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