Population-scale sequencing resolves determinants of persistent EBV DNA.

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Title: Population-scale sequencing resolves determinants of persistent EBV DNA.
Authors: Nyeo SS; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Tri-Institutional Program in Computational Biology, Weill Cornell School of Medicine, New York, NY, USA., Cumming EM; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Burren OS; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Pagadala MS; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gutierrez JC; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Ali TA; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Tri-Institutional Program in Computational Biology, Weill Cornell School of Medicine, New York, NY, USA., Kida LC; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chen Y; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX, USA., Chu H; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Tri-Institutional Program in Computational Biology, Weill Cornell School of Medicine, New York, NY, USA., Hu F; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Zou XZ; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Hollis B; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Fabre MA; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., MacArthur S; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Wang Q; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Ludwig LS; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology (BIMSB), Berlin, Germany., Dey KK; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Petrovski S; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK. slav.petrovski@astrazeneca.com., Dhindsa RS; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX, USA. Ryan.Dhindsa@bcm.edu.; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA. Ryan.Dhindsa@bcm.edu.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA. Ryan.Dhindsa@bcm.edu., Lareau CA; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. lareauc@mskcc.org.
Source: Nature [Nature] 2026 Feb; Vol. 650 (8102), pp. 664-672. Date of Electronic Publication: 2026 Jan 28.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: Population-scale sequencing resolves determinants of persistent EBV DNA.
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  Data: <searchLink fieldCode="AU" term="%22Nyeo+SS%22">Nyeo SS</searchLink>; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Tri-Institutional Program in Computational Biology, Weill Cornell School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Cumming+EM%22">Cumming EM</searchLink>; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Burren+OS%22">Burren OS</searchLink>; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Pagadala+MS%22">Pagadala MS</searchLink>; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Gutierrez+JC%22">Gutierrez JC</searchLink>; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ali+TA%22">Ali TA</searchLink>; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Tri-Institutional Program in Computational Biology, Weill Cornell School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kida+LC%22">Kida LC</searchLink>; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX, USA.; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Chu+H%22">Chu H</searchLink>; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Tri-Institutional Program in Computational Biology, Weill Cornell School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hu+F%22">Hu F</searchLink>; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Zou+XZ%22">Zou XZ</searchLink>; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Hollis+B%22">Hollis B</searchLink>; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Fabre+MA%22">Fabre MA</searchLink>; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22MacArthur+S%22">MacArthur S</searchLink>; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Ludwig+LS%22">Ludwig LS</searchLink>; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology (BIMSB), Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Dey+KK%22">Dey KK</searchLink>; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Petrovski+S%22">Petrovski S</searchLink>; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK. slav.petrovski@astrazeneca.com.<br /><searchLink fieldCode="AU" term="%22Dhindsa+RS%22">Dhindsa RS</searchLink>; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX, USA. Ryan.Dhindsa@bcm.edu.; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA. Ryan.Dhindsa@bcm.edu.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA. Ryan.Dhindsa@bcm.edu.<br /><searchLink fieldCode="AU" term="%22Lareau+CA%22">Lareau CA</searchLink>; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. lareauc@mskcc.org.
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  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2026 Feb; Vol. 650 (8102), pp. 664-672. <i>Date of Electronic Publication: </i>2026 Jan 28.
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