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Multitargeted Aza-Arylcarboxamides for Neurodegenerative Diseases: Potent Histamine H3 Receptor Ligands with Anticholinesterase and Metal-Chelating Activities.

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Title: Multitargeted Aza-Arylcarboxamides for Neurodegenerative Diseases: Potent Histamine H3 Receptor Ligands with Anticholinesterase and Metal-Chelating Activities.
Authors: Lopes FB; Department of Pharmaceutical Sciences, Federal University of São Paulo, Diadema 09913-030, Brazil.; Department of Medicine, Federal University of São Paulo, São Paulo 04023-062, Brazil., Werner T; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Duesseldorf 40225, Germany., Bagatin IA; Department of Chemistry, Federal University of São Paulo, Diadema 09972-270, Brazil., Stark H; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Duesseldorf 40225, Germany., Fernandes JPS; Department of Pharmaceutical Sciences, Federal University of São Paulo, Diadema 09913-030, Brazil.
Source: ACS chemical neuroscience [ACS Chem Neurosci] 2026 Mar 04; Vol. 17 (5), pp. 998-1014. Date of Electronic Publication: 2026 Jan 29.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Multitargeted Aza-Arylcarboxamides for Neurodegenerative Diseases: Potent Histamine H<subscript>3</subscript> Receptor Ligands with Anticholinesterase and Metal-Chelating Activities.
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  Data: <searchLink fieldCode="AU" term="%22Lopes+FB%22">Lopes FB</searchLink>; Department of Pharmaceutical Sciences, Federal University of São Paulo, Diadema 09913-030, Brazil.; Department of Medicine, Federal University of São Paulo, São Paulo 04023-062, Brazil.<br /><searchLink fieldCode="AU" term="%22Werner+T%22">Werner T</searchLink>; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Duesseldorf 40225, Germany.<br /><searchLink fieldCode="AU" term="%22Bagatin+IA%22">Bagatin IA</searchLink>; Department of Chemistry, Federal University of São Paulo, Diadema 09972-270, Brazil.<br /><searchLink fieldCode="AU" term="%22Stark+H%22">Stark H</searchLink>; Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Duesseldorf 40225, Germany.<br /><searchLink fieldCode="AU" term="%22Fernandes+JPS%22">Fernandes JPS</searchLink>; Department of Pharmaceutical Sciences, Federal University of São Paulo, Diadema 09913-030, Brazil.
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  Data: <searchLink fieldCode="JN" term="%22101525337%22">ACS chemical neuroscience</searchLink> [ACS Chem Neurosci] 2026 Mar 04; Vol. 17 (5), pp. 998-1014. <i>Date of Electronic Publication: </i>2026 Jan 29.
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        Value: 10.1021/acschemneuro.5c00803
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              Text: 2026 Mar 04
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