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Cancer Incidence and Mortality With Aspirin in Older Adults: Follow-Up of the ASPREE Trial.

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Title: Cancer Incidence and Mortality With Aspirin in Older Adults: Follow-Up of the ASPREE Trial.
Authors: Orchard SG; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia., Polekhina G; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia., Zalcberg J; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia., Bernstein W; Department of Medical Oncology, Walter Reed National Military Medical Center, Bethesda, Maryland.; Uniformed Services University of Health Sciences, Bethesda, Maryland., Macrae F; Department of Gastroenterology, The Royal Melbourne Hospital, Melbourne, Victoria, Australia., Tie J; Personalised Oncology Division, Walter and Eliza Hall Institute for Medical Research, Melbourne, Victoria, Australia.; Department of Medical Oncology, Peter MacCallum Cancer Centre, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia., Gately L; Personalised Oncology Division, Walter and Eliza Hall Institute for Medical Research, Melbourne, Victoria, Australia.; Department of Medical Oncology, Alfred Health, Melbourne, Victoria, Australia., Mar V; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia., Millar J; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia.; Department of Radiation Oncology, Alfred Health, Melbourne, Victoria, Australia., Rodriguez LM; National Cancer Institute, Division of Cancer Prevention, Bethesda, Maryland.; Department of Surgery, Walter Reed National Military Medical Center, Bethesda, Maryland., van Londen GJ; Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania., Kent A; Department of Radiation Oncology, Alfred Health, Melbourne, Victoria, Australia., Hiscutt E; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia.; Victorian Melanoma Service, Alfred Health, Victorian Melanoma Service, Alfred Hospital, Melbourne, Victoria, Australia., Ong WL; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia.; Department of Radiation Oncology, Alfred Health, Melbourne, Victoria, Australia., Warner ET; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston., Ford L; National Cancer Institute, Division of Cancer Prevention, Bethesda, Maryland., Umar A; National Cancer Institute, Division of Cancer Prevention, Bethesda, Maryland., McNeil JJ; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia., Nelson M; Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia., Stocks N; Discipline of General Practice, University of Adelaide, Adelaide SA, Australia., Shah RC; Department of Family & Preventive Medicine and the Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois., Kirpach B; Berman Centre for Outcomes and Clinical Research, Hennepin Healthcare Research Institute, Division of Geriatrics, Department of Medicine Hennepin HealthCare, Minneapolis, Minnesota., Murray A; Berman Centre for Outcomes and Clinical Research, Hennepin Healthcare Research Institute, Division of Geriatrics, Department of Medicine Hennepin HealthCare, Minneapolis, Minnesota.; University of Minnesota, Minneapolis., Woods RL; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia., Ryan J; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia., Wolfe R; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia., Gibbs P; Personalised Oncology Division, Walter and Eliza Hall Institute for Medical Research, Melbourne, Victoria, Australia.; Department of Medical Oncology, Peter MacCallum Cancer Centre, Victoria, Australia., Chan AT; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston.
Source: JAMA oncology [JAMA Oncol] 2026 Mar 01; Vol. 12 (3), pp. 285-294.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101652861 Publication Model: Print Cited Medium: Internet ISSN: 2374-2445 (Electronic) Linking ISSN: 23742437 NLM ISO Abbreviation: JAMA Oncol Subsets: MEDLINE
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  Data: Cancer Incidence and Mortality With Aspirin in Older Adults: Follow-Up of the ASPREE Trial.
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  Data: <searchLink fieldCode="AU" term="%22Orchard+SG%22">Orchard SG</searchLink>; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Polekhina+G%22">Polekhina G</searchLink>; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Zalcberg+J%22">Zalcberg J</searchLink>; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Bernstein+W%22">Bernstein W</searchLink>; Department of Medical Oncology, Walter Reed National Military Medical Center, Bethesda, Maryland.; Uniformed Services University of Health Sciences, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Macrae+F%22">Macrae F</searchLink>; Department of Gastroenterology, The Royal Melbourne Hospital, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Tie+J%22">Tie J</searchLink>; Personalised Oncology Division, Walter and Eliza Hall Institute for Medical Research, Melbourne, Victoria, Australia.; Department of Medical Oncology, Peter MacCallum Cancer Centre, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Gately+L%22">Gately L</searchLink>; Personalised Oncology Division, Walter and Eliza Hall Institute for Medical Research, Melbourne, Victoria, Australia.; Department of Medical Oncology, Alfred Health, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Mar+V%22">Mar V</searchLink>; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Millar+J%22">Millar J</searchLink>; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia.; Department of Radiation Oncology, Alfred Health, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Rodriguez+LM%22">Rodriguez LM</searchLink>; National Cancer Institute, Division of Cancer Prevention, Bethesda, Maryland.; Department of Surgery, Walter Reed National Military Medical Center, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22van+Londen+GJ%22">van Londen GJ</searchLink>; Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Kent+A%22">Kent A</searchLink>; Department of Radiation Oncology, Alfred Health, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Hiscutt+E%22">Hiscutt E</searchLink>; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia.; Victorian Melanoma Service, Alfred Health, Victorian Melanoma Service, Alfred Hospital, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Ong+WL%22">Ong WL</searchLink>; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia.; Department of Radiation Oncology, Alfred Health, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Warner+ET%22">Warner ET</searchLink>; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston.<br /><searchLink fieldCode="AU" term="%22Ford+L%22">Ford L</searchLink>; National Cancer Institute, Division of Cancer Prevention, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Umar+A%22">Umar A</searchLink>; National Cancer Institute, Division of Cancer Prevention, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22McNeil+JJ%22">McNeil JJ</searchLink>; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Nelson+M%22">Nelson M</searchLink>; Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.<br /><searchLink fieldCode="AU" term="%22Stocks+N%22">Stocks N</searchLink>; Discipline of General Practice, University of Adelaide, Adelaide SA, Australia.<br /><searchLink fieldCode="AU" term="%22Shah+RC%22">Shah RC</searchLink>; Department of Family & Preventive Medicine and the Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Kirpach+B%22">Kirpach B</searchLink>; Berman Centre for Outcomes and Clinical Research, Hennepin Healthcare Research Institute, Division of Geriatrics, Department of Medicine Hennepin HealthCare, Minneapolis, Minnesota.<br /><searchLink fieldCode="AU" term="%22Murray+A%22">Murray A</searchLink>; Berman Centre for Outcomes and Clinical Research, Hennepin Healthcare Research Institute, Division of Geriatrics, Department of Medicine Hennepin HealthCare, Minneapolis, Minnesota.; University of Minnesota, Minneapolis.<br /><searchLink fieldCode="AU" term="%22Woods+RL%22">Woods RL</searchLink>; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Ryan+J%22">Ryan J</searchLink>; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Wolfe+R%22">Wolfe R</searchLink>; School of Public Health and Preventive Medicine, Monash University, Melbourne Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Gibbs+P%22">Gibbs P</searchLink>; Personalised Oncology Division, Walter and Eliza Hall Institute for Medical Research, Melbourne, Victoria, Australia.; Department of Medical Oncology, Peter MacCallum Cancer Centre, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Chan+AT%22">Chan AT</searchLink>; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston.
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