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Integrated single-cell and bulk RNA sequencing unravels neutrophil heterogeneity and validates SPP1 as a prognostic biomarker in cervical cancer.

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Title: Integrated single-cell and bulk RNA sequencing unravels neutrophil heterogeneity and validates SPP1 as a prognostic biomarker in cervical cancer.
Authors: Lin S; Department of Ultrasound, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, 510630, China., Zhong J; Department of Ultrasound, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, 510630, China., Yuan S; Southern Medical University, Guangzhou, Guangdong, China., Su M; Department of Ultrasound, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, 510630, China., Zhang Y; Department of Pathology, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, Guangdong, China. zhangyw49@mail.sysu.edu.cn., Zhang X; Department of Ultrasound, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, 510630, China. zhxinl@mail.sysu.edu.cn.
Source: BMC cancer [BMC Cancer] 2026 Jan 30; Vol. 26 (1). Date of Electronic Publication: 2026 Jan 30.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Integrated single-cell and bulk RNA sequencing unravels neutrophil heterogeneity and validates SPP1 as a prognostic biomarker in cervical cancer.
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  Data: <searchLink fieldCode="AU" term="%22Lin+S%22">Lin S</searchLink>; Department of Ultrasound, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, 510630, China.<br /><searchLink fieldCode="AU" term="%22Zhong+J%22">Zhong J</searchLink>; Department of Ultrasound, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, 510630, China.<br /><searchLink fieldCode="AU" term="%22Yuan+S%22">Yuan S</searchLink>; Southern Medical University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Su+M%22">Su M</searchLink>; Department of Ultrasound, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, 510630, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Pathology, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510630, Guangdong, China. zhangyw49@mail.sysu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Department of Ultrasound, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province, 510630, China. zhxinl@mail.sysu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22100967800%22">BMC cancer</searchLink> [BMC Cancer] 2026 Jan 30; Vol. 26 (1). <i>Date of Electronic Publication: </i>2026 Jan 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100967800 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-2407 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214712407%22">14712407 </searchLink><i>NLM ISO Abbreviation: </i>BMC Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12885-026-15636-9
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        Text: English
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      – TitleFull: Integrated single-cell and bulk RNA sequencing unravels neutrophil heterogeneity and validates SPP1 as a prognostic biomarker in cervical cancer.
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              Text: 2026 Jan 30
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