Therapeutic delivery of albumin-binding siRNA targeting IRS2 to diverse cell types reduces mammary tumor growth.
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| Title: | Therapeutic delivery of albumin-binding siRNA targeting IRS2 to diverse cell types reduces mammary tumor growth. |
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| Authors: | Tocheny CE; Department of Molecular, Cell & Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Buchwald JE; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Dahlke CD; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Fakih HH; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Morgan JS; Department of Molecular, Cell & Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Summers A; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Silva CA; Department of Molecular, Cell & Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Jackson SO; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Lee JS; Department of Molecular, Cell & Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Card MA; Department of Molecular, Cell & Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Echeverria D; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Peterson C; Department of Comparative Pathobiology, Tufts University Cummings School of Veterinary Medicine, North Grafton, MA 01536, USA., Mercurio AM; Department of Molecular, Cell & Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Khvorova A; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA., Shaw LM; Department of Molecular, Cell & Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA. Electronic address: leslie.shaw@umassmed.edu. |
| Source: | Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2026 May 06; Vol. 34 (5), pp. 2963-2982. Date of Electronic Publication: 2026 Jan 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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