Epithelial extracellular vesicles induce inflammation and neutrophil activation in the Pseudomonas aeruginosa infected cystic fibrosis bronchial epithelium.

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Title: Epithelial extracellular vesicles induce inflammation and neutrophil activation in the Pseudomonas aeruginosa infected cystic fibrosis bronchial epithelium.
Authors: Hirsch MJ; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, United States., Tsai KY; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States., Jones LI; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States., Morales AN; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States., McIntire-Ray HJ; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States., Howze Iv PH; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States., Barnes JW; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, United States., Margaroli C; Department of Pathology, Division of Molecular and Cellular Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States., Genschmer K; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States., Krick S; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, United States.
Source: Frontiers in immunology [Front Immunol] 2026 Jan 14; Vol. 16, pp. 1659951. Date of Electronic Publication: 2026 Jan 14 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: Epithelial extracellular vesicles induce inflammation and neutrophil activation in the Pseudomonas aeruginosa infected cystic fibrosis bronchial epithelium.
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  Data: <searchLink fieldCode="AU" term="%22Hirsch+MJ%22">Hirsch MJ</searchLink>; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, United States.<br /><searchLink fieldCode="AU" term="%22Tsai+KY%22">Tsai KY</searchLink>; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.<br /><searchLink fieldCode="AU" term="%22Jones+LI%22">Jones LI</searchLink>; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.<br /><searchLink fieldCode="AU" term="%22Morales+AN%22">Morales AN</searchLink>; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.<br /><searchLink fieldCode="AU" term="%22McIntire-Ray+HJ%22">McIntire-Ray HJ</searchLink>; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.<br /><searchLink fieldCode="AU" term="%22Howze+Iv+PH%22">Howze Iv PH</searchLink>; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.<br /><searchLink fieldCode="AU" term="%22Barnes+JW%22">Barnes JW</searchLink>; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, United States.<br /><searchLink fieldCode="AU" term="%22Margaroli+C%22">Margaroli C</searchLink>; Department of Pathology, Division of Molecular and Cellular Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.<br /><searchLink fieldCode="AU" term="%22Genschmer+K%22">Genschmer K</searchLink>; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.<br /><searchLink fieldCode="AU" term="%22Krick+S%22">Krick S</searchLink>; Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL, United States.
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              Text: 2026 Jan 14
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