Unveiling relative lymphopenia and elevated monocyte-to-lymphocyte count as novel independent adverse prognostic factors in chronic myelomonocytic leukemia (CMML)-Proposal of the objective prognostic index for CMML (OPIC).
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| Title: | Unveiling relative lymphopenia and elevated monocyte-to-lymphocyte count as novel independent adverse prognostic factors in chronic myelomonocytic leukemia (CMML)-Proposal of the objective prognostic index for CMML (OPIC). |
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| Authors: | Calvo X; Laboratori de Citologia Hematologica Servei de Patologia, Grup de Recerca Translacional en Neoplasies Hematologiques (GRETNHE), Hospital del Mar Research Institute Barcelona Spain., Rial-Villavecchia A; Servei de Medicina Interna, Hospital del Mar, Programa de doctorat de Medicina i Recerca Translacional Universitat de Barcelona (UB) Spain., Roman-Bravo D; Laboratori de Citologia Hematologica Servei de Patologia, Grup de Recerca Translacional en Neoplasies Hematologiques (GRETNHE), Hospital del Mar Research Institute Barcelona Spain., Garcia-Avila S; Servei d'Hematologia Clínica, Grup de Recerca Clínica Aplicada en Neoplasies Hematològiques, Hospital del Mar Research Institute Barcelona Spain., Gomez-Perez L; Servei d'Hematologia Clínica, Grup de Recerca Clínica Aplicada en Neoplasies Hematològiques, Hospital del Mar Research Institute Barcelona Spain., Salido M; Laboratori de Citogenètica Molecular Servei de Patologia, GRETNHE, Hospital del Mar Research Institute Barcelona Spain., Puiggros A; Laboratori de Citogenètica Molecular Servei de Patologia, GRETNHE, Hospital del Mar Research Institute Barcelona Spain., Espinet B; Laboratori de Citogenètica Molecular Servei de Patologia, GRETNHE, Hospital del Mar Research Institute Barcelona Spain., Fernandez-Rodriguez C; Laboratori de Biologia Molecular Servei de Patologia, Grup de Recerca Clínica Aplicada en Neoplàsies Hematològiques, Hospital del Mar Research Institute Barcelona Spain., Tazon-Vega B; Laboratori de Biologia Molecular Servei de Patologia, Grup de Recerca Clínica Aplicada en Neoplàsies Hematològiques, Hospital del Mar Research Institute Barcelona Spain., Bellosillo B; Laboratori de Biologia Molecular Servei de Patologia, Grup de Recerca Clínica Aplicada en Neoplàsies Hematològiques, Hospital del Mar Research Institute Barcelona Spain., Castaño-Díez S; Servei d'Hematologia, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain., Díaz-Beyá M; Servei d'Hematologia, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain., Esteve J; Servei d'Hematologia, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain., Lome C; Servei de Patologia, Hospital del Mar Research Institute Barcelona Spain., Colomo L; Servei de Patologia, Hospital del Mar Research Institute Barcelona Spain.; Departament de Ciències Experimentals i de la Salut Universitat Pompeu Fabra Barcelona Spain., Florensa L; Laboratori de Citologia Hematologica Servei de Patologia, Grup de Recerca Translacional en Neoplasies Hematologiques (GRETNHE), Hospital del Mar Research Institute Barcelona Spain., Ferrer Del Álamo A; Laboratori de Citologia Hematologica Servei de Patologia, Grup de Recerca Translacional en Neoplasies Hematologiques (GRETNHE), Hospital del Mar Research Institute Barcelona Spain.; Departament de Ciències Experimentals i de la Salut Universitat Pompeu Fabra Barcelona Spain., Rodriguez-Sevilla JJ; Servei d'Hematologia, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain., Arenillas L; Laboratori de Citologia Hematologica Servei de Patologia, Grup de Recerca Translacional en Neoplasies Hematologiques (GRETNHE), Hospital del Mar Research Institute Barcelona Spain. |
| Source: | HemaSphere [Hemasphere] 2026 Jan 28; Vol. 10 (1), pp. e70286. Date of Electronic Publication: 2026 Jan 28 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 101740619 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-9241 (Electronic) Linking ISSN: 25729241 NLM ISO Abbreviation: Hemasphere Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41613280 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Unveiling relative lymphopenia and elevated monocyte-to-lymphocyte count as novel independent adverse prognostic factors in chronic myelomonocytic leukemia (CMML)-Proposal of the objective prognostic index for CMML (OPIC). – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Calvo+X%22">Calvo X</searchLink>; Laboratori de Citologia Hematologica Servei de Patologia, Grup de Recerca Translacional en Neoplasies Hematologiques (GRETNHE), Hospital del Mar Research Institute Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Rial-Villavecchia+A%22">Rial-Villavecchia A</searchLink>; Servei de Medicina Interna, Hospital del Mar, Programa de doctorat de Medicina i Recerca Translacional Universitat de Barcelona (UB) Spain.<br /><searchLink fieldCode="AU" term="%22Roman-Bravo+D%22">Roman-Bravo D</searchLink>; Laboratori de Citologia Hematologica Servei de Patologia, Grup de Recerca Translacional en Neoplasies Hematologiques (GRETNHE), Hospital del Mar Research Institute Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Garcia-Avila+S%22">Garcia-Avila S</searchLink>; Servei d'Hematologia Clínica, Grup de Recerca Clínica Aplicada en Neoplasies Hematològiques, Hospital del Mar Research Institute Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Gomez-Perez+L%22">Gomez-Perez L</searchLink>; Servei d'Hematologia Clínica, Grup de Recerca Clínica Aplicada en Neoplasies Hematològiques, Hospital del Mar Research Institute Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Salido+M%22">Salido M</searchLink>; Laboratori de Citogenètica Molecular Servei de Patologia, GRETNHE, Hospital del Mar Research Institute Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Puiggros+A%22">Puiggros A</searchLink>; Laboratori de Citogenètica Molecular Servei de Patologia, GRETNHE, Hospital del Mar Research Institute Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Espinet+B%22">Espinet B</searchLink>; Laboratori de Citogenètica Molecular Servei de Patologia, GRETNHE, Hospital del Mar Research Institute Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Fernandez-Rodriguez+C%22">Fernandez-Rodriguez C</searchLink>; Laboratori de Biologia Molecular Servei de Patologia, Grup de Recerca Clínica Aplicada en Neoplàsies Hematològiques, Hospital del Mar Research Institute Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Tazon-Vega+B%22">Tazon-Vega B</searchLink>; Laboratori de Biologia Molecular Servei de Patologia, Grup de Recerca Clínica Aplicada en Neoplàsies Hematològiques, Hospital del Mar Research Institute Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Bellosillo+B%22">Bellosillo B</searchLink>; Laboratori de Biologia Molecular Servei de Patologia, Grup de Recerca Clínica Aplicada en Neoplàsies Hematològiques, Hospital del Mar Research Institute Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Castaño-Díez+S%22">Castaño-Díez S</searchLink>; Servei d'Hematologia, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Díaz-Beyá+M%22">Díaz-Beyá M</searchLink>; Servei d'Hematologia, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Esteve+J%22">Esteve J</searchLink>; Servei d'Hematologia, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Lome+C%22">Lome C</searchLink>; Servei de Patologia, Hospital del Mar Research Institute Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Colomo+L%22">Colomo L</searchLink>; Servei de Patologia, Hospital del Mar Research Institute Barcelona Spain.; Departament de Ciències Experimentals i de la Salut Universitat Pompeu Fabra Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Florensa+L%22">Florensa L</searchLink>; Laboratori de Citologia Hematologica Servei de Patologia, Grup de Recerca Translacional en Neoplasies Hematologiques (GRETNHE), Hospital del Mar Research Institute Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Ferrer+Del+Álamo+A%22">Ferrer Del Álamo A</searchLink>; Laboratori de Citologia Hematologica Servei de Patologia, Grup de Recerca Translacional en Neoplasies Hematologiques (GRETNHE), Hospital del Mar Research Institute Barcelona Spain.; Departament de Ciències Experimentals i de la Salut Universitat Pompeu Fabra Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Rodriguez-Sevilla+JJ%22">Rodriguez-Sevilla JJ</searchLink>; Servei d'Hematologia, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer Barcelona Spain.<br /><searchLink fieldCode="AU" term="%22Arenillas+L%22">Arenillas L</searchLink>; Laboratori de Citologia Hematologica Servei de Patologia, Grup de Recerca Translacional en Neoplasies Hematologiques (GRETNHE), Hospital del Mar Research Institute Barcelona Spain. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101740619%22">HemaSphere</searchLink> [Hemasphere] 2026 Jan 28; Vol. 10 (1), pp. e70286. <i>Date of Electronic Publication: </i>2026 Jan 28 (<i>Print Publication: </i>2026). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101740619 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2572-9241 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225729241%22">25729241 </searchLink><i>NLM ISO Abbreviation: </i>Hemasphere <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41613280 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/hem3.70286 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e70286 Titles: – TitleFull: Unveiling relative lymphopenia and elevated monocyte-to-lymphocyte count as novel independent adverse prognostic factors in chronic myelomonocytic leukemia (CMML)-Proposal of the objective prognostic index for CMML (OPIC). Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Calvo X – PersonEntity: Name: NameFull: Rial-Villavecchia A – PersonEntity: Name: NameFull: Roman-Bravo D – PersonEntity: Name: NameFull: Garcia-Avila S – PersonEntity: Name: NameFull: Gomez-Perez L – PersonEntity: Name: NameFull: Salido M – PersonEntity: Name: NameFull: Puiggros A – PersonEntity: Name: NameFull: Espinet B – PersonEntity: Name: NameFull: Fernandez-Rodriguez C – PersonEntity: Name: NameFull: Tazon-Vega B – PersonEntity: Name: NameFull: Bellosillo B – PersonEntity: Name: NameFull: Castaño-Díez S – PersonEntity: Name: NameFull: Díaz-Beyá M – PersonEntity: Name: NameFull: Esteve J – PersonEntity: Name: NameFull: Lome C – PersonEntity: Name: NameFull: Colomo L – PersonEntity: Name: NameFull: Florensa L – PersonEntity: Name: NameFull: Ferrer Del Álamo A – PersonEntity: Name: NameFull: Rodriguez-Sevilla JJ – PersonEntity: Name: NameFull: Arenillas L IsPartOfRelationships: – BibEntity: Dates: – D: 28 M: 01 Text: 2026 Jan 28 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2572-9241 Numbering: – Type: volume Value: 10 – Type: issue Value: 1 Titles: – TitleFull: HemaSphere Type: main |
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