Molecular features of human pathological tau distinguish tauopathy-associated dementias.

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Title: Molecular features of human pathological tau distinguish tauopathy-associated dementias.
Authors: Kumar M; F.M. Kirby Neurobiology Center, Department of Neurobiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA., Schlaffner CN; F.M. Kirby Neurobiology Center, Department of Neurobiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA; Data Analytics and Computational Statistics, Hasso Plattner Institute, Digital Engineering Faculty, University of Potsdam, Potsdam, Germany., Tang S; F.M. Kirby Neurobiology Center, Department of Neurobiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA; Department of Biostatistics, Massey Comprehensive Cancer Center, Virginia Commonwealth University, Richmond, VA, USA., Beuvink MA; F.M. Kirby Neurobiology Center, Department of Neurobiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA., Viode A; Departments of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA., Mair W; F.M. Kirby Neurobiology Center, Department of Neurobiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA., Jha M; Departments of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA., Uncu C; F.M. Kirby Neurobiology Center, Department of Neurobiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA., Wesseling H; F.M. Kirby Neurobiology Center, Department of Neurobiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA., Wang T; F.M. Kirby Neurobiology Center, Department of Neurobiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA., Oakley DH; Massachusetts Alzheimer's Disease Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Beerepoot P; F.M. Kirby Neurobiology Center, Department of Neurobiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA., Xue J; F.M. Kirby Neurobiology Center, Department of Neurobiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA., Connors TR; Massachusetts Alzheimer's Disease Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Davis DA; UMMG Department of Neurology, Miller School of Medicine, Medical Campus, University of Miami, Miami, FL, USA., Frosch MP; Massachusetts Alzheimer's Disease Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Murray ME; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Spina SE; Memory and Aging Center, Department of Neurology and Pathology, University of California, San Francisco, San Francisco, CA, USA., Grinberg LT; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Seeley WW; Memory and Aging Center, Department of Neurology and Pathology, University of California, San Francisco, San Francisco, CA, USA., Miller BL; Memory and Aging Center, Department of Neurology and Pathology, University of California, San Francisco, San Francisco, CA, USA., Boxer AL; Memory and Aging Center, Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Geschwind DH; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Kosik KS; Neuroscience Research Institute and Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA, USA., Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Renard BY; Data Analytics and Computational Statistics, Hasso Plattner Institute, Digital Engineering Faculty, University of Potsdam, Potsdam, Germany., DeTure M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., McKee AC; Boston University Alzheimer's Disease and CTE Center, Boston University School of Medicine, Boston, MA, USA., Hyman BT; Massachusetts Alzheimer's Disease Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Steen H; F.M. Kirby Neurobiology Center, Department of Neurobiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA; Departments of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA., Steen JA; F.M. Kirby Neurobiology Center, Department of Neurobiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA. Electronic address: judith.steen@childrens.harvard.edu.
Source: Cell [Cell] 2026 Feb 05; Vol. 189 (3), pp. 956-968.e13. Date of Electronic Publication: 2026 Jan 29.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
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