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¹H-NMR serum metabolomic profiling from clinical routine identifies signatures of progressive melanoma metastasis.

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Title: ¹H-NMR serum metabolomic profiling from clinical routine identifies signatures of progressive melanoma metastasis.
Authors: Gellrich FF; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. frankfriedrich.gellrich@ukdd.de.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany. frankfriedrich.gellrich@ukdd.de., Hufnagel C; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany., Funk AM; Institute for Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden, 01307, Dresden, Germany., Jonas S; Institute for Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden, 01307, Dresden, Germany., Altmann H; BioBank Dresden, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; National Center for Tumor Diseases, Dresden (NCT/UCC), Dresden, Germany., Hobelsberger S; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany., Steininger J; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany., Rauschenberg R; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany., Garzarolli M; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany., Lehr S; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany., Pöschman L; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany., Biedermann P; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany., Schatz JS; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany., Feige C; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany., Tasdogan A; Department of Dermatology, University Hospital Essen & German Cancer Consortium (DKTK), Partner Site Essen, Essen, Germany.; National Center for Tumour diseases (NCT-West), Campus Essen & Research Alliance Ruhr,, Research Center One Health, University Duisburg-Essen, Essen, Germany., Chavakis T; Institute for Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden, 01307, Dresden, Germany., Beissert S; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Meier F; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany., Mirtschink P; Institute for Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden, 01307, Dresden, Germany., Steiner G; Department of Anesthesia and Intensive Care, Clinical Sensoring and Monitoring, Faculty of Medicine Carl Gustav Carus, University Hospital, Technische Universität Dresden, Dresden, Germany.
Source: Scientific reports [Sci Rep] 2026 Jan 30; Vol. 16 (1), pp. 5263. Date of Electronic Publication: 2026 Jan 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: ¹H-NMR serum metabolomic profiling from clinical routine identifies signatures of progressive melanoma metastasis.
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  Data: <searchLink fieldCode="AU" term="%22Gellrich+FF%22">Gellrich FF</searchLink>; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. frankfriedrich.gellrich@ukdd.de.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany. frankfriedrich.gellrich@ukdd.de.<br /><searchLink fieldCode="AU" term="%22Hufnagel+C%22">Hufnagel C</searchLink>; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Funk+AM%22">Funk AM</searchLink>; Institute for Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden, 01307, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Jonas+S%22">Jonas S</searchLink>; Institute for Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden, 01307, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Altmann+H%22">Altmann H</searchLink>; BioBank Dresden, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; National Center for Tumor Diseases, Dresden (NCT/UCC), Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Hobelsberger+S%22">Hobelsberger S</searchLink>; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Steininger+J%22">Steininger J</searchLink>; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Rauschenberg+R%22">Rauschenberg R</searchLink>; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Garzarolli+M%22">Garzarolli M</searchLink>; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Lehr+S%22">Lehr S</searchLink>; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Pöschman+L%22">Pöschman L</searchLink>; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Biedermann+P%22">Biedermann P</searchLink>; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Schatz+JS%22">Schatz JS</searchLink>; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Feige+C%22">Feige C</searchLink>; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Tasdogan+A%22">Tasdogan A</searchLink>; Department of Dermatology, University Hospital Essen & German Cancer Consortium (DKTK), Partner Site Essen, Essen, Germany.; National Center for Tumour diseases (NCT-West), Campus Essen & Research Alliance Ruhr,, Research Center One Health, University Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Chavakis+T%22">Chavakis T</searchLink>; Institute for Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden, 01307, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Beissert+S%22">Beissert S</searchLink>; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Meier+F%22">Meier F</searchLink>; Department of Dermatology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Skin Cancer Center at the University Cancer Center and National Center for Tumor Diseases Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Mirtschink+P%22">Mirtschink P</searchLink>; Institute for Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden, 01307, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Steiner+G%22">Steiner G</searchLink>; Department of Anesthesia and Intensive Care, Clinical Sensoring and Monitoring, Faculty of Medicine Carl Gustav Carus, University Hospital, Technische Universität Dresden, Dresden, Germany.
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