Mapping cellular vulnerability in Parkinson's disease using retro-AAVs and preformed α-synuclein fibrils.

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Title: Mapping cellular vulnerability in Parkinson's disease using retro-AAVs and preformed α-synuclein fibrils.
Authors: Geibl FF; Department of Psychiatry and Psychotherapy, Marburg University, Rudolf-Bultmann-Str. 8, 35043, Marburg, Germany.; Department of Neurology, Marburg University, 35043, Marburg, Germany.; Department of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Musa AAS; Department of Psychiatry and Psychotherapy, Marburg University, Rudolf-Bultmann-Str. 8, 35043, Marburg, Germany.; Department of Neurology, Marburg University, 35043, Marburg, Germany., Dietrich L; Department of Psychiatry and Psychotherapy, Marburg University, Rudolf-Bultmann-Str. 8, 35043, Marburg, Germany.; Department of Neurology, Marburg University, 35043, Marburg, Germany., Wolter H; Department of Psychiatry and Psychotherapy, Marburg University, Rudolf-Bultmann-Str. 8, 35043, Marburg, Germany.; Department of Neurology, Marburg University, 35043, Marburg, Germany., Wokosin DL; Department of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Khudayberdiev S; Molecular Neurobiology Group, Institute of Physiological Chemistry, Marburg University, 35032, Marburg, Germany.; Center for Mind, Brain and Behavior (CMBB), University of Marburg and Justus-Liebig-University Giessen, 35032, Marburg, Germany., Rust MB; Molecular Neurobiology Group, Institute of Physiological Chemistry, Marburg University, 35032, Marburg, Germany.; Center for Mind, Brain and Behavior (CMBB), University of Marburg and Justus-Liebig-University Giessen, 35032, Marburg, Germany., Chen R; Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Dawson VL; Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Department of Physiology, Pharmacology and Therapeutics, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Dawson TM; Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Department of Physiology, Pharmacology and Therapeutics, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland, 20815, USA., Oertel WH; Department of Neurology, Marburg University, 35043, Marburg, Germany., Surmeier DJ; Department of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, Maryland, 20815, USA., Henrich MT; Department of Psychiatry and Psychotherapy, Marburg University, Rudolf-Bultmann-Str. 8, 35043, Marburg, Germany. martin.henrich@uni-marburg.de.; Department of Neurology, Marburg University, 35043, Marburg, Germany. martin.henrich@uni-marburg.de.; Department of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA. martin.henrich@uni-marburg.de.
Source: Translational neurodegeneration [Transl Neurodegener] 2026 Jan 30; Vol. 15 (1), pp. 2. Date of Electronic Publication: 2026 Jan 30.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101591861 Publication Model: Electronic Cited Medium: Print ISSN: 2047-9158 (Print) Linking ISSN: 20479158 NLM ISO Abbreviation: Transl Neurodegener Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2047-9158
DOI:10.1186/s40035-026-00535-7