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VEXAS syndrome and cancer: Insights about a possible "Tip of the Iceberg". Ambidirectional data from the international AIDA network registries.

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Title: VEXAS syndrome and cancer: Insights about a possible "Tip of the Iceberg". Ambidirectional data from the international AIDA network registries.
Authors: Gavioli F; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Caggiano V; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Sbalchiero J; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Frassi M; Rheumatology and Clinical Immunology, Spedali Civili and Department of Clinical and Experimental Sciences, University of Brescia, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Brescia, Italy., Crisafulli F; Rheumatology and Clinical Immunology, Spedali Civili and Department of Clinical and Experimental Sciences, University of Brescia, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Brescia, Italy., Cavazzana I; Rheumatology and Clinical Immunology, Spedali Civili and Department of Clinical and Experimental Sciences, University of Brescia, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Brescia, Italy., Hinojosa-Azaola A; Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Martín-Nares E; Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Guaracha-Basañez GA; Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Torres-Ruiz J; Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Wiesik-Szewczyk E; Department of Internal Medicine, Pneumonology, Allergology, Clinical Immunology and Rare Diseases, Military Institute of Medicine, National Research Institute, Warsaw, Poland., Sfriso P; Rheumatology Unit, Department of Medicine, University of Padua, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Padua, Italy., Rizzo S; Rheumatology Unit, Department of Medicine, University of Padua, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Padua, Italy., Schermi M; Rheumatology Unit, Department of Medicine, University of Padua, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Padua, Italy., Bindoli S; Rheumatology Unit, Department of Medicine, University of Padua, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Padua, Italy., Hernández-Rodríguez J; Clinical Unit of Autoinflammatory Diseases, Department of Autoimmune Diseases, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic of Barcelona [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], University of Barcelona, Barcelona, Spain., Gómez-Caverzaschi V; Clinical Unit of Autoinflammatory Diseases, Department of Autoimmune Diseases, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic of Barcelona [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], University of Barcelona, Barcelona, Spain., Araújo O; Clinical Unit of Autoinflammatory Diseases, Department of Autoimmune Diseases, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic of Barcelona [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], University of Barcelona, Barcelona, Spain., Alemanno A; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Giardini HAM; Rheumatology Division, Faculdade de Medicina, Hospital das Clínicas, Universidade de São Paulo, São Paulo, Brazil., González-García A; Systemic Autoimmune Diseases Unit, Department of Internal Medicine, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain., Placido F; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Lopalco G; Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J) Policlinic Hospital, University of Bari, Bari, Italy., Viapiana O; Rheumatology Unit, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Italy., Tufan A; Department of Internal Medicine, Division of Rheumatology, Gazi University Hospital, Ankara, Turkiye., Koksoy B; Department of Internal Medicine, Division of Rheumatology, Gazi University Hospital, Ankara, Turkiye., Mulayim F; Department of Medical Genetics, Gazi University Hospital, Ankara, Turkey., Hissaria P; Department of Clinical Immunology and Allergy, Royal Adelaide Hospital, Adelaide, Australia; Department of Immunopathology, SA Pathology, Adelaide, Australia., Beecher M; Department of Clinical Immunology and Allergy, Royal Adelaide Hospital, Adelaide, Australia; Department of Immunopathology, SA Pathology, Adelaide, Australia., Panayiaris T; Department of Clinical Immunology and Allergy, Royal Adelaide Hospital, Adelaide, Australia; Department of Immunopathology, SA Pathology, Adelaide, Australia., De Paulis A; Department of Translational Medical Sciences, Section of Clinical Immunology, University of Naples Federico II, Naples, Italy; Center for Basic and Clinical Immunology Research (CISI), WAO Center of Excellence, University of Naples Federico II, Naples, Italy., Dagna L; Division of Immunology, Transplants and Infectious Diseases, Università Vita-Salute San Raffaele, Milan, Italy; Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS Ospedale San Raffaele, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Milan, Italy., Tomelleri A; Division of Immunology, Transplants and Infectious Diseases, Università Vita-Salute San Raffaele, Milan, Italy; Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS Ospedale San Raffaele, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Milan, Italy., Campochiaro C; Division of Immunology, Transplants and Infectious Diseases, Università Vita-Salute San Raffaele, Milan, Italy; Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS Ospedale San Raffaele, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Milan, Italy., Bugatti S; Department of Internal Medicine and Therapeutics, Università di Pavia, Italy; Division of Rheumatology, Fondazione IRCCS Policlinico San Matteo, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Pavia, Italy., Milanesi A; Department of Internal Medicine and Therapeutics, Università di Pavia, Italy; Division of Rheumatology, Fondazione IRCCS Policlinico San Matteo, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Pavia, Italy., Ruiz-Irastorza G; Faculty of Medicine and Nursery, University of the Basque Country, UPV/EHU, Leioa, Biscay, Spain; Autoimmune Diseases Unit, Biocruces Bizkaia Health Research Institute, Barakaldo, Biscay, Spain., Soto-Peleteiro A; Faculty of Medicine and Nursery, University of the Basque Country, UPV/EHU, Leioa, Biscay, Spain; Autoimmune Diseases Unit, Biocruces Bizkaia Health Research Institute, Barakaldo, Biscay, Spain., Piga M; Rheumatology Unit, Department of Medical Sciences and Public Health, University of Cagliari and AOU of Cagliari, Cagliari, Italy., Cauli A; Rheumatology Unit, Department of Medical Sciences and Public Health, University of Cagliari and AOU of Cagliari, Cagliari, Italy., Floris A; Rheumatology Unit, Department of Medical Sciences and Public Health, University of Cagliari and AOU of Cagliari, Cagliari, Italy., Conti F; Department of medical and cardiovascular Sciences, Rheumatology Unit, Sapienza University of Rome, Viale del Policlinico 155, 00185 Rome, Italy., Cardamone C; UOC of Internal Medicine, Rheumatology Outpatients Unit, Azienda Ospedaliero-Universitaria San Giovanni di Dio e Ruggi D'Aragona, Via San Leonardo 1, Salerno, Italy., Zorzenon I; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Triggianese P; Division of Geriatric and Nutrition, Department of Medical Sciences, Fondazione PTV Policlinico Tor Vergata, Rome, Italy; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy., Gurnari C; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy; Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA., Vitetta R; Unit of Rheumatology, ASL VC Sant' Andrea Hospital, Vercelli 13100, Italy., Prete M; Rheumatic and Systemic Autoimmune Diseases Unit, Department of Interdisciplinary Medicine (DIM), University of Bari Medical School, Bari, Italy., Racanelli V; Centre for Medical Sciences, University of Trento and Internal Medicine Division, Santa Chiara Hospital, Provincial Health Care Agency (APSS), Trento, Italy., Silvan F; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Talarico R; Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Mayo-Juanatey A; Department of Rheumatology, Doctor Peset University Hospital, Valencia, Spain., Alegre-Sancho JJ; Department of Rheumatology, Doctor Peset University Hospital, Valencia, Spain., Renieri A; Medical Genetics, Department of Medical Biotechnologies, University of Siena, Siena, Italy; Department of Medical Biotechnologies, Med Biotech Hub and Competence Center, University of Siena, Siena, Italy; Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy., Bocchia M; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy; Hematology, Azienda Ospedaliero-Universitaria Senese, University of Siena, Siena, Italy., Sicuranza A; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy; Hematology, Azienda Ospedaliero-Universitaria Senese, University of Siena, Siena, Italy., Balistreri A; Bioengineering and Biomedical Data Science Lab, Department of Medical Biotechnologies, University of Siena, Siena, Italy., Sorrentino V; Molecular Medicine Section, Department of Molecular and Developmental Medicine, University of Siena, I-53100 Siena, Italy., Frullanti E; Cancer Genomics & Systems Biology Laboratory, University of Siena, 53100 Siena, Italy; Med Biotech Hub and Competence Centre, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy., Frediani B; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy., Fabiani C; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy; Ophthalmology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Italy., Cantarini L; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy. Electronic address: cantariniluca@hotmail.com., Vitale A; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy.
Source: Seminars in arthritis and rheumatism [Semin Arthritis Rheum] 2026 Apr; Vol. 77, pp. 152932. Date of Electronic Publication: 2026 Jan 22.
Publication Type: Journal Article
Journal Info: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 1306053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-866X (Electronic) Linking ISSN: 00490172 NLM ISO Abbreviation: Semin Arthritis Rheum Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: VEXAS syndrome and cancer: Insights about a possible "Tip of the Iceberg". Ambidirectional data from the international AIDA network registries.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Gavioli+F%22">Gavioli F</searchLink>; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Caggiano+V%22">Caggiano V</searchLink>; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Sbalchiero+J%22">Sbalchiero J</searchLink>; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Frassi+M%22">Frassi M</searchLink>; Rheumatology and Clinical Immunology, Spedali Civili and Department of Clinical and Experimental Sciences, University of Brescia, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Crisafulli+F%22">Crisafulli F</searchLink>; Rheumatology and Clinical Immunology, Spedali Civili and Department of Clinical and Experimental Sciences, University of Brescia, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Cavazzana+I%22">Cavazzana I</searchLink>; Rheumatology and Clinical Immunology, Spedali Civili and Department of Clinical and Experimental Sciences, University of Brescia, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Brescia, Italy.<br /><searchLink fieldCode="AU" term="%22Hinojosa-Azaola+A%22">Hinojosa-Azaola A</searchLink>; Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Martín-Nares+E%22">Martín-Nares E</searchLink>; Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Guaracha-Basañez+GA%22">Guaracha-Basañez GA</searchLink>; Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Torres-Ruiz+J%22">Torres-Ruiz J</searchLink>; Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Wiesik-Szewczyk+E%22">Wiesik-Szewczyk E</searchLink>; Department of Internal Medicine, Pneumonology, Allergology, Clinical Immunology and Rare Diseases, Military Institute of Medicine, National Research Institute, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Sfriso+P%22">Sfriso P</searchLink>; Rheumatology Unit, Department of Medicine, University of Padua, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Rizzo+S%22">Rizzo S</searchLink>; Rheumatology Unit, Department of Medicine, University of Padua, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Schermi+M%22">Schermi M</searchLink>; Rheumatology Unit, Department of Medicine, University of Padua, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Bindoli+S%22">Bindoli S</searchLink>; Rheumatology Unit, Department of Medicine, University of Padua, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Hernández-Rodríguez+J%22">Hernández-Rodríguez J</searchLink>; Clinical Unit of Autoinflammatory Diseases, Department of Autoimmune Diseases, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic of Barcelona [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Gómez-Caverzaschi+V%22">Gómez-Caverzaschi V</searchLink>; Clinical Unit of Autoinflammatory Diseases, Department of Autoimmune Diseases, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic of Barcelona [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Araújo+O%22">Araújo O</searchLink>; Clinical Unit of Autoinflammatory Diseases, Department of Autoimmune Diseases, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic of Barcelona [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Alemanno+A%22">Alemanno A</searchLink>; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Giardini+HAM%22">Giardini HAM</searchLink>; Rheumatology Division, Faculdade de Medicina, Hospital das Clínicas, Universidade de São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22González-García+A%22">González-García A</searchLink>; Systemic Autoimmune Diseases Unit, Department of Internal Medicine, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Placido+F%22">Placido F</searchLink>; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Lopalco+G%22">Lopalco G</searchLink>; Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J) Policlinic Hospital, University of Bari, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Viapiana+O%22">Viapiana O</searchLink>; Rheumatology Unit, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Tufan+A%22">Tufan A</searchLink>; Department of Internal Medicine, Division of Rheumatology, Gazi University Hospital, Ankara, Turkiye.<br /><searchLink fieldCode="AU" term="%22Koksoy+B%22">Koksoy B</searchLink>; Department of Internal Medicine, Division of Rheumatology, Gazi University Hospital, Ankara, Turkiye.<br /><searchLink fieldCode="AU" term="%22Mulayim+F%22">Mulayim F</searchLink>; Department of Medical Genetics, Gazi University Hospital, Ankara, Turkey.<br /><searchLink fieldCode="AU" term="%22Hissaria+P%22">Hissaria P</searchLink>; Department of Clinical Immunology and Allergy, Royal Adelaide Hospital, Adelaide, Australia; Department of Immunopathology, SA Pathology, Adelaide, Australia.<br /><searchLink fieldCode="AU" term="%22Beecher+M%22">Beecher M</searchLink>; Department of Clinical Immunology and Allergy, Royal Adelaide Hospital, Adelaide, Australia; Department of Immunopathology, SA Pathology, Adelaide, Australia.<br /><searchLink fieldCode="AU" term="%22Panayiaris+T%22">Panayiaris T</searchLink>; Department of Clinical Immunology and Allergy, Royal Adelaide Hospital, Adelaide, Australia; Department of Immunopathology, SA Pathology, Adelaide, Australia.<br /><searchLink fieldCode="AU" term="%22De+Paulis+A%22">De Paulis A</searchLink>; Department of Translational Medical Sciences, Section of Clinical Immunology, University of Naples Federico II, Naples, Italy; Center for Basic and Clinical Immunology Research (CISI), WAO Center of Excellence, University of Naples Federico II, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Dagna+L%22">Dagna L</searchLink>; Division of Immunology, Transplants and Infectious Diseases, Università Vita-Salute San Raffaele, Milan, Italy; Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS Ospedale San Raffaele, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Tomelleri+A%22">Tomelleri A</searchLink>; Division of Immunology, Transplants and Infectious Diseases, Università Vita-Salute San Raffaele, Milan, Italy; Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS Ospedale San Raffaele, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Campochiaro+C%22">Campochiaro C</searchLink>; Division of Immunology, Transplants and Infectious Diseases, Università Vita-Salute San Raffaele, Milan, Italy; Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS Ospedale San Raffaele, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bugatti+S%22">Bugatti S</searchLink>; Department of Internal Medicine and Therapeutics, Università di Pavia, Italy; Division of Rheumatology, Fondazione IRCCS Policlinico San Matteo, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Milanesi+A%22">Milanesi A</searchLink>; Department of Internal Medicine and Therapeutics, Università di Pavia, Italy; Division of Rheumatology, Fondazione IRCCS Policlinico San Matteo, [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center], Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Ruiz-Irastorza+G%22">Ruiz-Irastorza G</searchLink>; Faculty of Medicine and Nursery, University of the Basque Country, UPV/EHU, Leioa, Biscay, Spain; Autoimmune Diseases Unit, Biocruces Bizkaia Health Research Institute, Barakaldo, Biscay, Spain.<br /><searchLink fieldCode="AU" term="%22Soto-Peleteiro+A%22">Soto-Peleteiro A</searchLink>; Faculty of Medicine and Nursery, University of the Basque Country, UPV/EHU, Leioa, Biscay, Spain; Autoimmune Diseases Unit, Biocruces Bizkaia Health Research Institute, Barakaldo, Biscay, Spain.<br /><searchLink fieldCode="AU" term="%22Piga+M%22">Piga M</searchLink>; Rheumatology Unit, Department of Medical Sciences and Public Health, University of Cagliari and AOU of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Cauli+A%22">Cauli A</searchLink>; Rheumatology Unit, Department of Medical Sciences and Public Health, University of Cagliari and AOU of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Floris+A%22">Floris A</searchLink>; Rheumatology Unit, Department of Medical Sciences and Public Health, University of Cagliari and AOU of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Conti+F%22">Conti F</searchLink>; Department of medical and cardiovascular Sciences, Rheumatology Unit, Sapienza University of Rome, Viale del Policlinico 155, 00185 Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Cardamone+C%22">Cardamone C</searchLink>; UOC of Internal Medicine, Rheumatology Outpatients Unit, Azienda Ospedaliero-Universitaria San Giovanni di Dio e Ruggi D'Aragona, Via San Leonardo 1, Salerno, Italy.<br /><searchLink fieldCode="AU" term="%22Zorzenon+I%22">Zorzenon I</searchLink>; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Triggianese+P%22">Triggianese P</searchLink>; Division of Geriatric and Nutrition, Department of Medical Sciences, Fondazione PTV Policlinico Tor Vergata, Rome, Italy; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Gurnari+C%22">Gurnari C</searchLink>; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy; Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Vitetta+R%22">Vitetta R</searchLink>; Unit of Rheumatology, ASL VC Sant' Andrea Hospital, Vercelli 13100, Italy.<br /><searchLink fieldCode="AU" term="%22Prete+M%22">Prete M</searchLink>; Rheumatic and Systemic Autoimmune Diseases Unit, Department of Interdisciplinary Medicine (DIM), University of Bari Medical School, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Racanelli+V%22">Racanelli V</searchLink>; Centre for Medical Sciences, University of Trento and Internal Medicine Division, Santa Chiara Hospital, Provincial Health Care Agency (APSS), Trento, Italy.<br /><searchLink fieldCode="AU" term="%22Silvan+F%22">Silvan F</searchLink>; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Talarico+R%22">Talarico R</searchLink>; Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Mayo-Juanatey+A%22">Mayo-Juanatey A</searchLink>; Department of Rheumatology, Doctor Peset University Hospital, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Alegre-Sancho+JJ%22">Alegre-Sancho JJ</searchLink>; Department of Rheumatology, Doctor Peset University Hospital, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Renieri+A%22">Renieri A</searchLink>; Medical Genetics, Department of Medical Biotechnologies, University of Siena, Siena, Italy; Department of Medical Biotechnologies, Med Biotech Hub and Competence Center, University of Siena, Siena, Italy; Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Bocchia+M%22">Bocchia M</searchLink>; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy; Hematology, Azienda Ospedaliero-Universitaria Senese, University of Siena, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Sicuranza+A%22">Sicuranza A</searchLink>; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy; Hematology, Azienda Ospedaliero-Universitaria Senese, University of Siena, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Balistreri+A%22">Balistreri A</searchLink>; Bioengineering and Biomedical Data Science Lab, Department of Medical Biotechnologies, University of Siena, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Sorrentino+V%22">Sorrentino V</searchLink>; Molecular Medicine Section, Department of Molecular and Developmental Medicine, University of Siena, I-53100 Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Frullanti+E%22">Frullanti E</searchLink>; Cancer Genomics & Systems Biology Laboratory, University of Siena, 53100 Siena, Italy; Med Biotech Hub and Competence Centre, Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Frediani+B%22">Frediani B</searchLink>; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Fabiani+C%22">Fabiani C</searchLink>; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy; Ophthalmology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Cantarini+L%22">Cantarini L</searchLink>; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy. Electronic address: cantariniluca@hotmail.com.<br /><searchLink fieldCode="AU" term="%22Vitale+A%22">Vitale A</searchLink>; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese [European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (RITA) Center] Siena, Italy.
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  Data: <searchLink fieldCode="JN" term="%221306053%22">Seminars in arthritis and rheumatism</searchLink> [Semin Arthritis Rheum] 2026 Apr; Vol. 77, pp. 152932. <i>Date of Electronic Publication: </i>2026 Jan 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22W%2EB%2E+Saunders%22">W.B. Saunders </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1306053 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-866X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200490172%22">00490172 </searchLink><i>NLM ISO Abbreviation: </i>Semin Arthritis Rheum <i>Subsets: </i>MEDLINE
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