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Polygenic risk scores for pediatric obsessive-compulsive symptoms: Mediating effects in samples clinically diagnosed with mental disorders.

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Title: Polygenic risk scores for pediatric obsessive-compulsive symptoms: Mediating effects in samples clinically diagnosed with mental disorders.
Authors: Antonyan L; Mathison Centre for Mental Health Research and Education, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary AB, Canada. Electronic address: lilit.antonyan1@ucalgary.ca., Shaheen SM; Mathison Centre for Mental Health Research and Education, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary AB, Canada., Burton CL; Department of Neurosciences and Mental Health, Hospital for Sick Children, Toronto, ON, Canada., Gehring WJ; Department of Psychology, University of Michigan, Ann Arbor MI, USA., Soreni N; Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada., Szura PF; Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit MI, USA., Bellamy J; Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit MI, USA., Rajan U; Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit MI, USA., Rosenberg D; Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit MI, USA., Hanna GL; Department of Psychiatry, University of Michigan, Ann Arbor MI, USA., Arnold PD; Mathison Centre for Mental Health Research and Education, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary AB, Canada. Electronic address: paul.arnold@ucalgary.ca.
Source: Psychiatry research [Psychiatry Res] 2026 Apr; Vol. 358, pp. 116977. Date of Electronic Publication: 2026 Jan 27.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Ireland NLM ID: 7911385 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7123 (Electronic) Linking ISSN: 01651781 NLM ISO Abbreviation: Psychiatry Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Polygenic risk scores for pediatric obsessive-compulsive symptoms: Mediating effects in samples clinically diagnosed with mental disorders.
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  Data: <searchLink fieldCode="AU" term="%22Antonyan+L%22">Antonyan L</searchLink>; Mathison Centre for Mental Health Research and Education, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary AB, Canada. Electronic address: lilit.antonyan1@ucalgary.ca.<br /><searchLink fieldCode="AU" term="%22Shaheen+SM%22">Shaheen SM</searchLink>; Mathison Centre for Mental Health Research and Education, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary AB, Canada.<br /><searchLink fieldCode="AU" term="%22Burton+CL%22">Burton CL</searchLink>; Department of Neurosciences and Mental Health, Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Gehring+WJ%22">Gehring WJ</searchLink>; Department of Psychology, University of Michigan, Ann Arbor MI, USA.<br /><searchLink fieldCode="AU" term="%22Soreni+N%22">Soreni N</searchLink>; Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Szura+PF%22">Szura PF</searchLink>; Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit MI, USA.<br /><searchLink fieldCode="AU" term="%22Bellamy+J%22">Bellamy J</searchLink>; Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit MI, USA.<br /><searchLink fieldCode="AU" term="%22Rajan+U%22">Rajan U</searchLink>; Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit MI, USA.<br /><searchLink fieldCode="AU" term="%22Rosenberg+D%22">Rosenberg D</searchLink>; Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit MI, USA.<br /><searchLink fieldCode="AU" term="%22Hanna+GL%22">Hanna GL</searchLink>; Department of Psychiatry, University of Michigan, Ann Arbor MI, USA.<br /><searchLink fieldCode="AU" term="%22Arnold+PD%22">Arnold PD</searchLink>; Mathison Centre for Mental Health Research and Education, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary AB, Canada. Electronic address: paul.arnold@ucalgary.ca.
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              Text: 2026 Apr
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