Co-editing of NKG2A and FAS increases long-term cytotoxic capacity and persistence of CAR NK cells.

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Title: Co-editing of NKG2A and FAS increases long-term cytotoxic capacity and persistence of CAR NK cells.
Authors: Mietz J; Cellular Immunotherapy, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Egli L; Cellular Immunotherapy, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Misiune M; Cellular Immunotherapy, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Picozzi A; Cellular Immunotherapy, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Coianiz N; Cellular Immunotherapy, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Thompson D; Viral Immunobiology, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Ponzo M; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland., Charmey A; Department of Oncology, University Children's Hospital Zurich, Zurich, Switzerland., Bornhauser B; Department of Oncology, University Children's Hospital Zurich, Zurich, Switzerland., Magnani CF; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland., Münz C; Viral Immunobiology, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Chijioke O; Cellular Immunotherapy, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.
Source: Molecular therapy. Oncology [Mol Ther Oncol] 2026 Jan 09; Vol. 34 (1), pp. 201126. Date of Electronic Publication: 2026 Jan 09 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 9918752083706676 Publication Model: eCollection Cited Medium: Print ISSN: 2950-3299 (Print) Linking ISSN: 29503299 NLM ISO Abbreviation: Mol Ther Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Co-editing of NKG2A and FAS increases long-term cytotoxic capacity and persistence of CAR NK cells.
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  Data: <searchLink fieldCode="AU" term="%22Mietz+J%22">Mietz J</searchLink>; Cellular Immunotherapy, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Egli+L%22">Egli L</searchLink>; Cellular Immunotherapy, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Misiune+M%22">Misiune M</searchLink>; Cellular Immunotherapy, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Picozzi+A%22">Picozzi A</searchLink>; Cellular Immunotherapy, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Coianiz+N%22">Coianiz N</searchLink>; Cellular Immunotherapy, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Thompson+D%22">Thompson D</searchLink>; Viral Immunobiology, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ponzo+M%22">Ponzo M</searchLink>; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Charmey+A%22">Charmey A</searchLink>; Department of Oncology, University Children's Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bornhauser+B%22">Bornhauser B</searchLink>; Department of Oncology, University Children's Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Magnani+CF%22">Magnani CF</searchLink>; Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Münz+C%22">Münz C</searchLink>; Viral Immunobiology, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Chijioke+O%22">Chijioke O</searchLink>; Cellular Immunotherapy, Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.
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  Data: <searchLink fieldCode="JN" term="%229918752083706676%22">Molecular therapy. Oncology</searchLink> [Mol Ther Oncol] 2026 Jan 09; Vol. 34 (1), pp. 201126. <i>Date of Electronic Publication: </i>2026 Jan 09 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Inc%22">Elsevier Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9918752083706676 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2950-3299 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2229503299%22">29503299 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther Oncol <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1016/j.omton.2026.201126
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              Text: 2026 Jan 09
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