An integrative algorithm combining HLA epitope registry, PIRCHE-T2, and PIRCHE-B outcomes to improve immunological risk stratification in kidney transplantation.

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Title: An integrative algorithm combining HLA epitope registry, PIRCHE-T2, and PIRCHE-B outcomes to improve immunological risk stratification in kidney transplantation.
Authors: Zhao H; Department of Obstetrics and Gynecology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China.; Histocompatibility and Immunogenetics Laboratory, St. Paul's Hospital, Saskatoon, SK, Canada.; College of Graduate and Postdoctoral Studies, University of Saskatchewan, Saskatoon, SK, Canada., Kakodkar P; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK, Canada., Wang E; College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada., Zhang D; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK, Canada., Niemann M; PIRCHE AG, Research and Development, Berlin, Germany., Webster D; Histocompatibility and Immunogenetics Laboratory, St. Paul's Hospital, Saskatoon, SK, Canada., Pearce T; Histocompatibility and Immunogenetics Laboratory, St. Paul's Hospital, Saskatoon, SK, Canada., Shoker A; Saskatchewan Transplant Program, Saskatchewan Health Authority, Saskatoon, SK, Canada., Keown P; Vancouver Coastal Health, University of British Columbia, Vancouver, BC, Canada., Sherwood K; Vancouver Coastal Health, University of British Columbia, Vancouver, BC, Canada., Wu F; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK, Canada.; Department of Pathology, Brigham and Women's Hospital, Boston, MA, United States.; Harvard Medical School, Boston, MA, United States., Lewis C; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK, Canada., Mostafa A; Histocompatibility and Immunogenetics Laboratory, St. Paul's Hospital, Saskatoon, SK, Canada.; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
Source: Frontiers in immunology [Front Immunol] 2026 Jan 16; Vol. 16, pp. 1718506. Date of Electronic Publication: 2026 Jan 16 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: An integrative algorithm combining HLA epitope registry, PIRCHE-T2, and PIRCHE-B outcomes to improve immunological risk stratification in kidney transplantation.
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  Data: <searchLink fieldCode="AU" term="%22Zhao+H%22">Zhao H</searchLink>; Department of Obstetrics and Gynecology, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China.; Histocompatibility and Immunogenetics Laboratory, St. Paul's Hospital, Saskatoon, SK, Canada.; College of Graduate and Postdoctoral Studies, University of Saskatchewan, Saskatoon, SK, Canada.<br /><searchLink fieldCode="AU" term="%22Kakodkar+P%22">Kakodkar P</searchLink>; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK, Canada.<br /><searchLink fieldCode="AU" term="%22Wang+E%22">Wang E</searchLink>; College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada.<br /><searchLink fieldCode="AU" term="%22Zhang+D%22">Zhang D</searchLink>; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK, Canada.<br /><searchLink fieldCode="AU" term="%22Niemann+M%22">Niemann M</searchLink>; PIRCHE AG, Research and Development, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Webster+D%22">Webster D</searchLink>; Histocompatibility and Immunogenetics Laboratory, St. Paul's Hospital, Saskatoon, SK, Canada.<br /><searchLink fieldCode="AU" term="%22Pearce+T%22">Pearce T</searchLink>; Histocompatibility and Immunogenetics Laboratory, St. Paul's Hospital, Saskatoon, SK, Canada.<br /><searchLink fieldCode="AU" term="%22Shoker+A%22">Shoker A</searchLink>; Saskatchewan Transplant Program, Saskatchewan Health Authority, Saskatoon, SK, Canada.<br /><searchLink fieldCode="AU" term="%22Keown+P%22">Keown P</searchLink>; Vancouver Coastal Health, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Sherwood+K%22">Sherwood K</searchLink>; Vancouver Coastal Health, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Wu+F%22">Wu F</searchLink>; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK, Canada.; Department of Pathology, Brigham and Women's Hospital, Boston, MA, United States.; Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Lewis+C%22">Lewis C</searchLink>; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK, Canada.<br /><searchLink fieldCode="AU" term="%22Mostafa+A%22">Mostafa A</searchLink>; Histocompatibility and Immunogenetics Laboratory, St. Paul's Hospital, Saskatoon, SK, Canada.; Department of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Jan 16; Vol. 16, pp. 1718506. <i>Date of Electronic Publication: </i>2026 Jan 16 (<i>Print Publication: </i>2025).
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