Examining covariate-specific treatment effects in individual participant data meta-analysis: Framing aggregation bias in terms of trial-level confounding and funnel plots.
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| Title: | Examining covariate-specific treatment effects in individual participant data meta-analysis: Framing aggregation bias in terms of trial-level confounding and funnel plots. |
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| Authors: | Siegel LK; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Koopmeiners JS; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Hartmann-Boyce J; Department of Health Promotion and Policy, School of Public Health & Health Sciences, University of Massachusetts Amherst, Amherst, MA, USA., Godolphin PJ; MRC Clinical Trials Unit at UCL, University College London, London, UK., Babiker AG; MRC Clinical Trials Unit at UCL, University College London, London, UK., Touloumi G; Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece., Knowlton KU; Intermountain Medical Center, Intermountain Heart Institute, Salt Lake City, UT, USA., Riley RD; School of Health Sciences, University of Birmingham, Birmingham, UK; and National Institute for Health and Care Research (NIHR) Birmingham Biomedical Research Centre, UK. |
| Source: | Research synthesis methods [Res Synth Methods] 2026 Jan; Vol. 17 (1), pp. 194-209. Date of Electronic Publication: 2025 Oct 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley Blackwell Country of Publication: England NLM ID: 101543738 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1759-2887 (Electronic) Linking ISSN: 17592879 NLM ISO Abbreviation: Res Synth Methods Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41626891 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Examining covariate-specific treatment effects in individual participant data meta-analysis: Framing aggregation bias in terms of trial-level confounding and funnel plots. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Siegel+LK%22">Siegel LK</searchLink>; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Koopmeiners+JS%22">Koopmeiners JS</searchLink>; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Hartmann-Boyce+J%22">Hartmann-Boyce J</searchLink>; Department of Health Promotion and Policy, School of Public Health & Health Sciences, University of Massachusetts Amherst, Amherst, MA, USA.<br /><searchLink fieldCode="AU" term="%22Godolphin+PJ%22">Godolphin PJ</searchLink>; MRC Clinical Trials Unit at UCL, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Babiker+AG%22">Babiker AG</searchLink>; MRC Clinical Trials Unit at UCL, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Touloumi+G%22">Touloumi G</searchLink>; Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Knowlton+KU%22">Knowlton KU</searchLink>; Intermountain Medical Center, Intermountain Heart Institute, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Riley+RD%22">Riley RD</searchLink>; School of Health Sciences, University of Birmingham, Birmingham, UK; and National Institute for Health and Care Research (NIHR) Birmingham Biomedical Research Centre, UK. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101543738%22">Research synthesis methods</searchLink> [Res Synth Methods] 2026 Jan; Vol. 17 (1), pp. 194-209. <i>Date of Electronic Publication: </i>2025 Oct 23. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley+Blackwell%22">Wiley Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101543738 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1759-2887 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217592879%22">17592879 </searchLink><i>NLM ISO Abbreviation: </i>Res Synth Methods <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41626891 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1017/rsm.2025.10043 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 194 Titles: – TitleFull: Examining covariate-specific treatment effects in individual participant data meta-analysis: Framing aggregation bias in terms of trial-level confounding and funnel plots. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Siegel LK – PersonEntity: Name: NameFull: Koopmeiners JS – PersonEntity: Name: NameFull: Hartmann-Boyce J – PersonEntity: Name: NameFull: Godolphin PJ – PersonEntity: Name: NameFull: Babiker AG – PersonEntity: Name: NameFull: Touloumi G – PersonEntity: Name: NameFull: Knowlton KU – PersonEntity: Name: NameFull: Riley RD IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: 2026 Jan Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1759-2887 Numbering: – Type: volume Value: 17 – Type: issue Value: 1 Titles: – TitleFull: Research synthesis methods Type: main |
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