Polymorphisms in intron 1 of HLA-DRA differentially associate with type 1 diabetes and celiac disease and implicate involvement of complement system genes C4A and C4B.
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| Title: | Polymorphisms in intron 1 of HLA-DRA differentially associate with type 1 diabetes and celiac disease and implicate involvement of complement system genes C4A and C4B. |
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| Authors: | Aydemir O; University of Massachusetts Chan Medical School, Worcester, United States., Bailey JA; Department of Pathology and Laboratory Medicine and Center for Computational Molecular Biology, Brown University, Providence, United States., Agardh D; Department of Clinical Sciences, Lund University CRC Skane University Hospital, Malmö, Sweden., Lernmark Å; Department of Clinical Sciences, Lund University CRC Skane University Hospital, Malmö, Sweden., Noble JA; University of California, San Francisco, San Francisco, United States., Andersson Svärd A; Department of Clinical Sciences, Lund University CRC Skane University Hospital, Malmö, Sweden., Blankenhorn EP; Drexel University College of Medicine, Philadelphia, United States., Parikh HM; Health Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, United States., Ziegler AG; Institute of Diabetes Research, Helmholtz Zentrum München, Klinikum rechts der Isar, Technische Universität München, and Forschergruppe Diabetes e.V., Neuherberg, Germany., Toppari J; Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, and Centre for Population Health Research, University of Turku, Turku, Finland.; Department of Pediatrics, Turku University Hospital, Turku, Finland., Akolkar B; National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, United States., Hagopian WA; Pediatrics, Indiana University School of Medicine, Indianapolis, United States.; Department of Medicine, University of Washington, Seattle, United States., Rewers MJ; Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, United States., Mordes JP; University of Massachusetts Chan Medical School, Worcester, United States. |
| Corporate Authors: | TEDDY Study Group |
| Source: | ELife [Elife] 2026 Feb 02; Vol. 12. Date of Electronic Publication: 2026 Feb 02. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41627183 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Polymorphisms in intron 1 of HLA-DRA differentially associate with type 1 diabetes and celiac disease and implicate involvement of complement system genes C4A and C4B. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Aydemir+O%22">Aydemir O</searchLink>; University of Massachusetts Chan Medical School, Worcester, United States.<br /><searchLink fieldCode="AU" term="%22Bailey+JA%22">Bailey JA</searchLink>; Department of Pathology and Laboratory Medicine and Center for Computational Molecular Biology, Brown University, Providence, United States.<br /><searchLink fieldCode="AU" term="%22Agardh+D%22">Agardh D</searchLink>; Department of Clinical Sciences, Lund University CRC Skane University Hospital, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Lernmark+Å%22">Lernmark Å</searchLink>; Department of Clinical Sciences, Lund University CRC Skane University Hospital, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Noble+JA%22">Noble JA</searchLink>; University of California, San Francisco, San Francisco, United States.<br /><searchLink fieldCode="AU" term="%22Andersson+Svärd+A%22">Andersson Svärd A</searchLink>; Department of Clinical Sciences, Lund University CRC Skane University Hospital, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Blankenhorn+EP%22">Blankenhorn EP</searchLink>; Drexel University College of Medicine, Philadelphia, United States.<br /><searchLink fieldCode="AU" term="%22Parikh+HM%22">Parikh HM</searchLink>; Health Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, United States.<br /><searchLink fieldCode="AU" term="%22Ziegler+AG%22">Ziegler AG</searchLink>; Institute of Diabetes Research, Helmholtz Zentrum München, Klinikum rechts der Isar, Technische Universität München, and Forschergruppe Diabetes e.V., Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Toppari+J%22">Toppari J</searchLink>; Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, and Centre for Population Health Research, University of Turku, Turku, Finland.; Department of Pediatrics, Turku University Hospital, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Akolkar+B%22">Akolkar B</searchLink>; National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, United States.<br /><searchLink fieldCode="AU" term="%22Hagopian+WA%22">Hagopian WA</searchLink>; Pediatrics, Indiana University School of Medicine, Indianapolis, United States.; Department of Medicine, University of Washington, Seattle, United States.<br /><searchLink fieldCode="AU" term="%22Rewers+MJ%22">Rewers MJ</searchLink>; Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, United States.<br /><searchLink fieldCode="AU" term="%22Mordes+JP%22">Mordes JP</searchLink>; University of Massachusetts Chan Medical School, Worcester, United States. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22TEDDY+Study+Group%22">TEDDY Study Group</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101579614%22">ELife</searchLink> [Elife] 2026 Feb 02; Vol. 12. <i>Date of Electronic Publication: </i>2026 Feb 02. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22eLife+Sciences+Publications%2C+Ltd%22">eLife Sciences Publications, Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101579614 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2050-084X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222050084X%22">2050084X </searchLink><i>NLM ISO Abbreviation: </i>Elife <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41627183 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.7554/eLife.89068 Languages: – Code: eng Text: English Titles: – TitleFull: Polymorphisms in intron 1 of HLA-DRA differentially associate with type 1 diabetes and celiac disease and implicate involvement of complement system genes C4A and C4B. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Aydemir O – PersonEntity: Name: NameFull: Bailey JA – PersonEntity: Name: NameFull: Agardh D – PersonEntity: Name: NameFull: Lernmark Å – PersonEntity: Name: NameFull: Noble JA – PersonEntity: Name: NameFull: Andersson Svärd A – PersonEntity: Name: NameFull: Blankenhorn EP – PersonEntity: Name: NameFull: Parikh HM – PersonEntity: Name: NameFull: Ziegler AG – PersonEntity: Name: NameFull: Toppari J – PersonEntity: Name: NameFull: Akolkar B – PersonEntity: Name: NameFull: Hagopian WA – PersonEntity: Name: NameFull: Rewers MJ – PersonEntity: Name: NameFull: Mordes JP IsPartOfRelationships: – BibEntity: Dates: – D: 02 M: 02 Text: 2026 Feb 02 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2050-084X Numbering: – Type: volume Value: 12 Titles: – TitleFull: ELife Type: main |
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