Polymorphisms in intron 1 of HLA-DRA differentially associate with type 1 diabetes and celiac disease and implicate involvement of complement system genes C4A and C4B.
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| Title: | Polymorphisms in intron 1 of HLA-DRA differentially associate with type 1 diabetes and celiac disease and implicate involvement of complement system genes C4A and C4B. |
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| Authors: | Aydemir O; University of Massachusetts Chan Medical School, Worcester, United States., Bailey JA; Department of Pathology and Laboratory Medicine and Center for Computational Molecular Biology, Brown University, Providence, United States., Agardh D; Department of Clinical Sciences, Lund University CRC Skane University Hospital, Malmö, Sweden., Lernmark Å; Department of Clinical Sciences, Lund University CRC Skane University Hospital, Malmö, Sweden., Noble JA; University of California, San Francisco, San Francisco, United States., Andersson Svärd A; Department of Clinical Sciences, Lund University CRC Skane University Hospital, Malmö, Sweden., Blankenhorn EP; Drexel University College of Medicine, Philadelphia, United States., Parikh HM; Health Informatics Institute, Morsani College of Medicine, University of South Florida, Tampa, United States., Ziegler AG; Institute of Diabetes Research, Helmholtz Zentrum München, Klinikum rechts der Isar, Technische Universität München, and Forschergruppe Diabetes e.V., Neuherberg, Germany., Toppari J; Research Centre for Integrative Physiology and Pharmacology, Institute of Biomedicine, and Centre for Population Health Research, University of Turku, Turku, Finland.; Department of Pediatrics, Turku University Hospital, Turku, Finland., Akolkar B; National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, United States., Hagopian WA; Pediatrics, Indiana University School of Medicine, Indianapolis, United States.; Department of Medicine, University of Washington, Seattle, United States., Rewers MJ; Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, United States., Mordes JP; University of Massachusetts Chan Medical School, Worcester, United States. |
| Corporate Authors: | TEDDY Study Group |
| Source: | ELife [Elife] 2026 Feb 02; Vol. 12. Date of Electronic Publication: 2026 Feb 02. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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