ER remodelling is a feature of ageing and depends on ER-phagy.

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Title: ER remodelling is a feature of ageing and depends on ER-phagy.
Authors: Donahue EKF; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA., Hepowit NL; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA., Ruark EM; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA., Mulligan AG; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA., Keuchel B; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA., Urban ND; Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Peng L; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA., Stephens S; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, USA., Johnson DJ; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA., Wallace NS; Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA., Jackson LP; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, USA.; Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA., Ellisman MH; National Center for Microscopy and Imaging Research, Department of Neurosciences, University of California San Diego, La Jolla, CA, USA., Arrojo E Drigo R; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN, USA., Folkmann AW; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, USA., Truttmann MC; Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., MacGurn JA; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA., Burkewitz K; Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA. kristopher.burkewitz@vanderbilt.edu.
Source: Nature cell biology [Nat Cell Biol] 2026 Mar; Vol. 28 (3), pp. 449-464. Date of Electronic Publication: 2026 Feb 02.
Publication Type: Journal Article
Journal Info: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4679
DOI:10.1038/s41556-025-01860-1