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Mechanistic insights into the anti-benign prostatic hyperplasia effect of dihydromyricetin via suppression of the 5-AR/TGF-β1/Smad2 axis.

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Title: Mechanistic insights into the anti-benign prostatic hyperplasia effect of dihydromyricetin via suppression of the 5-AR/TGF-β1/Smad2 axis.
Authors: El-Hameed SSA; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Minia University, Minia, Egypt. sara.sameh@minia.edu.eg., Matouk AI; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Minia University, Minia, Egypt.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Minia National University (MNU), Minia, Egypt., Ibrahim ARN; Department of Biochemistry, Faculty of Pharmacy, Minia University, Minia, Egypt., El-Daly M; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Minia University, Minia, Egypt.; Department of Pharmacology, College of Pharmacy, King Khalid University, Abha, 62521, Saudi Arabia.
Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2026 Apr; Vol. 399 (7), pp. 10323-10339. Date of Electronic Publication: 2026 Feb 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22El-Hameed+SSA%22">El-Hameed SSA</searchLink>; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Minia University, Minia, Egypt. sara.sameh@minia.edu.eg.<br /><searchLink fieldCode="AU" term="%22Matouk+AI%22">Matouk AI</searchLink>; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Minia University, Minia, Egypt.; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Minia National University (MNU), Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22Ibrahim+ARN%22">Ibrahim ARN</searchLink>; Department of Biochemistry, Faculty of Pharmacy, Minia University, Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Daly+M%22">El-Daly M</searchLink>; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Minia University, Minia, Egypt.; Department of Pharmacology, College of Pharmacy, King Khalid University, Abha, 62521, Saudi Arabia.
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        Value: 10.1007/s00210-026-04998-3
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              Text: 2026 Apr
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