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Migraine-induced cochlear injury triggers ZBP1-mediated PANoptosis via CGRP signaling.

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Title: Migraine-induced cochlear injury triggers ZBP1-mediated PANoptosis via CGRP signaling.
Authors: Xu W; Department of Otorhinolaryngology, Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Zhai N; Department of Physiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.; Department of Pathophysiology, Shihezi University School of Medicine, Shihezi, 832002, China., Chen J; Department of Otorhinolaryngology, Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Zhou S; Department of Otorhinolaryngology, Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Tian E; Department of Otolaryngology, Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China., Guo Z; Department of Otorhinolaryngology, Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Zhou Z; Department of Otorhinolaryngology, Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Yu X; Department of Otorhinolaryngology, Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Zhai Z; Department of Otorhinolaryngology, Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Zhang X; Department of Otorhinolaryngology, Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China., Wang Y; Department of Otorhinolaryngology, Head and Neck Surgery, People's Hospital, Peking University, Beijing, 100871, China. yixu2007@163.com., Ma X; Department of Otorhinolaryngology, Head and Neck Surgery, People's Hospital, Peking University, Beijing, 100871, China. 13581709195@163.com., Lu Y; Department of Physiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. luys@hust.edu.cn., Zhang S; Department of Otorhinolaryngology, Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. sulin_zhang@hust.edu.cn.
Source: The journal of headache and pain [J Headache Pain] 2026 Feb 02; Vol. 27 (1). Date of Electronic Publication: 2026 Feb 02.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100940562 Publication Model: Electronic Cited Medium: Internet ISSN: 1129-2377 (Electronic) Linking ISSN: 11292369 NLM ISO Abbreviation: J Headache Pain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Migraine-induced cochlear injury triggers ZBP1-mediated PANoptosis via CGRP signaling.
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  Data: <searchLink fieldCode="AU" term="%22Xu+W%22">Xu W</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22Zhai+N%22">Zhai N</searchLink>; Department of Physiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.; Department of Pathophysiology, Shihezi University School of Medicine, Shihezi, 832002, China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22Zhou+S%22">Zhou S</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22Tian+E%22">Tian E</searchLink>; Department of Otolaryngology, Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.<br /><searchLink fieldCode="AU" term="%22Guo+Z%22">Guo Z</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22Zhou+Z%22">Zhou Z</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22Yu+X%22">Yu X</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22Zhai+Z%22">Zhai Z</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, People's Hospital, Peking University, Beijing, 100871, China. yixu2007@163.com.<br /><searchLink fieldCode="AU" term="%22Ma+X%22">Ma X</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, People's Hospital, Peking University, Beijing, 100871, China. 13581709195@163.com.<br /><searchLink fieldCode="AU" term="%22Lu+Y%22">Lu Y</searchLink>; Department of Physiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. luys@hust.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. sulin_zhang@hust.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22100940562%22">The journal of headache and pain</searchLink> [J Headache Pain] 2026 Feb 02; Vol. 27 (1). <i>Date of Electronic Publication: </i>2026 Feb 02.
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      – TitleFull: Migraine-induced cochlear injury triggers ZBP1-mediated PANoptosis via CGRP signaling.
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              Text: 2026 Feb 02
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