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Relationship between locus coeruleus and slow-wave sleep in aging and Alzheimer's disease.

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Title: Relationship between locus coeruleus and slow-wave sleep in aging and Alzheimer's disease.
Authors: Falgàs N; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain., Tort-Colet N; Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Hospital del Mar Research Institute, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain., Martín-Sobrino I; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain., Mayà G; Sleep Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Universitat de Barcelona, Barcelona, Spain., Peña-González M; Magnetic Resonance Imaging Core Facility, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Rudilosso S; Comprehensive Stroke Center, Department of Neuroscience, Hospital Clínic Barcelona, Barcelona, Spain.; August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain., Gaig C; Sleep Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Universitat de Barcelona, Barcelona, Spain., Bosch B; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain., Arqueros A; Sleep Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Universitat de Barcelona, Barcelona, Spain., Pérez-Millan A; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; eHealth Center, Faculty of Computer Science, Multimedia and Telecommunications, Universitat Oberta de Catalunya, Barcelona, Spain., Tort-Merino A; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain., Fernández-Villullas G; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain., Piñol-Ripoll G; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain., Balasa M; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain., Lladó A; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain., Ruiz MM; Biochemistry and Molecular Genetics Department-CDB, Hospital Clinic, IDIBAPS, CIBERehd, Barcelona, Spain., Muñoz-Moreno E; Magnetic Resonance Imaging Core Facility, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Grau-Rivera O; Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Hospital del Mar Research Institute, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain., Iranzo A; Sleep Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Universitat de Barcelona, Barcelona, Spain., Grinberg LT; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, Florida, USA.; Department of Neurology, Memory & Aging Center, Weill Institute for Neurosciences, University of California, San Francisco, California, USA.; Department of Pathology, University of Sao Paulo Medical School, Sao Paulo, Brazil., Sánchez-Valle R; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 Feb; Vol. 22 (2), pp. e71183.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Relationship between locus coeruleus and slow-wave sleep in aging and Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Falgàs+N%22">Falgàs N</searchLink>; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Tort-Colet+N%22">Tort-Colet N</searchLink>; Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Hospital del Mar Research Institute, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Martín-Sobrino+I%22">Martín-Sobrino I</searchLink>; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Mayà+G%22">Mayà G</searchLink>; Sleep Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Universitat de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Peña-González+M%22">Peña-González M</searchLink>; Magnetic Resonance Imaging Core Facility, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Rudilosso+S%22">Rudilosso S</searchLink>; Comprehensive Stroke Center, Department of Neuroscience, Hospital Clínic Barcelona, Barcelona, Spain.; August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Gaig+C%22">Gaig C</searchLink>; Sleep Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Universitat de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Bosch+B%22">Bosch B</searchLink>; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Arqueros+A%22">Arqueros A</searchLink>; Sleep Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Universitat de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Pérez-Millan+A%22">Pérez-Millan A</searchLink>; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.; eHealth Center, Faculty of Computer Science, Multimedia and Telecommunications, Universitat Oberta de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Tort-Merino+A%22">Tort-Merino A</searchLink>; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Fernández-Villullas+G%22">Fernández-Villullas G</searchLink>; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Piñol-Ripoll+G%22">Piñol-Ripoll G</searchLink>; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Balasa+M%22">Balasa M</searchLink>; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Lladó+A%22">Lladó A</searchLink>; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Ruiz+MM%22">Ruiz MM</searchLink>; Biochemistry and Molecular Genetics Department-CDB, Hospital Clinic, IDIBAPS, CIBERehd, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Muñoz-Moreno+E%22">Muñoz-Moreno E</searchLink>; Magnetic Resonance Imaging Core Facility, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Grau-Rivera+O%22">Grau-Rivera O</searchLink>; Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Hospital del Mar Research Institute, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Iranzo+A%22">Iranzo A</searchLink>; Sleep Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Universitat de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Grinberg+LT%22">Grinberg LT</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, Florida, USA.; Department of Neurology, Memory & Aging Center, Weill Institute for Neurosciences, University of California, San Francisco, California, USA.; Department of Pathology, University of Sao Paulo Medical School, Sao Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Sánchez-Valle+R%22">Sánchez-Valle R</searchLink>; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic de Barcelona, Fundació de Recerca Clínic Barcelona-IDIBAPS, Barcelona, Spain.; Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
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