Engineered miR-122 inhibitors preserve endothelial mitochondrial function and prevent vascular dysfunction in obesity-associated prediabetes.
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| Title: | Engineered miR-122 inhibitors preserve endothelial mitochondrial function and prevent vascular dysfunction in obesity-associated prediabetes. |
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| Authors: | Gaddam RR; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA., Pathuri M; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA., Deb P; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA., Dwivedi S; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA., Vikram A; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA., Kasina V; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA., Amalkar VS; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA., Lira V; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Department of Health, Sport, and Human Physiology, College of Liberal Arts and Sciences, University of Iowa, Iowa City, IA 52242, USA., Kaur H; Department of Pathology and Translational Pathobiology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71103, USA., Dhanesha N; Department of Pathology and Translational Pathobiology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71103, USA., Mangalam AK; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA., Bahal R; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA., Vikram A; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA. |
| Source: | Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2026 Jan 09; Vol. 37 (1), pp. 102830. Date of Electronic Publication: 2026 Jan 09 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101581621 Publication Model: eCollection Cited Medium: Print ISSN: 2162-2531 (Print) Linking ISSN: 21622531 NLM ISO Abbreviation: Mol Ther Nucleic Acids Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41630989 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Engineered miR-122 inhibitors preserve endothelial mitochondrial function and prevent vascular dysfunction in obesity-associated prediabetes. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Gaddam+RR%22">Gaddam RR</searchLink>; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.<br /><searchLink fieldCode="AU" term="%22Pathuri+M%22">Pathuri M</searchLink>; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA.<br /><searchLink fieldCode="AU" term="%22Deb+P%22">Deb P</searchLink>; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.<br /><searchLink fieldCode="AU" term="%22Dwivedi+S%22">Dwivedi S</searchLink>; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.<br /><searchLink fieldCode="AU" term="%22Vikram+A%22">Vikram A</searchLink>; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.<br /><searchLink fieldCode="AU" term="%22Kasina+V%22">Kasina V</searchLink>; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA.<br /><searchLink fieldCode="AU" term="%22Amalkar+VS%22">Amalkar VS</searchLink>; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.<br /><searchLink fieldCode="AU" term="%22Lira+V%22">Lira V</searchLink>; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Department of Health, Sport, and Human Physiology, College of Liberal Arts and Sciences, University of Iowa, Iowa City, IA 52242, USA.<br /><searchLink fieldCode="AU" term="%22Kaur+H%22">Kaur H</searchLink>; Department of Pathology and Translational Pathobiology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71103, USA.<br /><searchLink fieldCode="AU" term="%22Dhanesha+N%22">Dhanesha N</searchLink>; Department of Pathology and Translational Pathobiology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71103, USA.<br /><searchLink fieldCode="AU" term="%22Mangalam+AK%22">Mangalam AK</searchLink>; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.<br /><searchLink fieldCode="AU" term="%22Bahal+R%22">Bahal R</searchLink>; Department of Pharmaceutical Sciences, University of Connecticut, Storrs, CT 06269, USA.<br /><searchLink fieldCode="AU" term="%22Vikram+A%22">Vikram A</searchLink>; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.; Fraternal Order of Eagles Diabetes Research Center (FOEDRC), University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101581621%22">Molecular therapy. Nucleic acids</searchLink> [Mol Ther Nucleic Acids] 2026 Jan 09; Vol. 37 (1), pp. 102830. <i>Date of Electronic Publication: </i>2026 Jan 09 (<i>Print Publication: </i>2026). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101581621 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2162-2531 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221622531%22">21622531 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther Nucleic Acids <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41630989 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.omtn.2026.102830 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 102830 Titles: – TitleFull: Engineered miR-122 inhibitors preserve endothelial mitochondrial function and prevent vascular dysfunction in obesity-associated prediabetes. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Gaddam RR – PersonEntity: Name: NameFull: Pathuri M – PersonEntity: Name: NameFull: Deb P – PersonEntity: Name: NameFull: Dwivedi S – PersonEntity: Name: NameFull: Vikram A – PersonEntity: Name: NameFull: Kasina V – PersonEntity: Name: NameFull: Amalkar VS – PersonEntity: Name: NameFull: Lira V – PersonEntity: Name: NameFull: Kaur H – PersonEntity: Name: NameFull: Dhanesha N – PersonEntity: Name: NameFull: Mangalam AK – PersonEntity: Name: NameFull: Bahal R – PersonEntity: Name: NameFull: Vikram A IsPartOfRelationships: – BibEntity: Dates: – D: 09 M: 01 Text: 2026 Jan 09 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 2162-2531 Numbering: – Type: volume Value: 37 – Type: issue Value: 1 Titles: – TitleFull: Molecular therapy. Nucleic acids Type: main |
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