Antiplasmodial Activity and Pharmacokinetic Profiling of Cryptolepine and 2,7-Dibromocryptolepine With a View to Informing the Design of Novel Antimalarial Cryptolepine Analogues.

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Title: Antiplasmodial Activity and Pharmacokinetic Profiling of Cryptolepine and 2,7-Dibromocryptolepine With a View to Informing the Design of Novel Antimalarial Cryptolepine Analogues.
Authors: Chenu E; MMV Medicines for Malaria Venture, Meyrin, Switzerland., Duffy J; MMV Medicines for Malaria Venture, Meyrin, Switzerland., Forkuo AD; Department of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana., Gbedema SY; Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana., Abdelall S; School of Pharmacy and Medical Sciences, University of Bradford, Bradford, UK., Wahajuddin M; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, University of Bradford, Bradford, UK., Jones HS; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, University of Bradford, Bradford, UK., Wright CW; School of Pharmacy and Medical Sciences, University of Bradford, Bradford, UK.
Source: Drug development research [Drug Dev Res] 2026 Apr; Vol. 87 (2), pp. e70245.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8204468 Publication Model: Print Cited Medium: Internet ISSN: 1098-2299 (Electronic) Linking ISSN: 02724391 NLM ISO Abbreviation: Drug Dev Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Chenu+E%22">Chenu E</searchLink>; MMV Medicines for Malaria Venture, Meyrin, Switzerland.<br /><searchLink fieldCode="AU" term="%22Duffy+J%22">Duffy J</searchLink>; MMV Medicines for Malaria Venture, Meyrin, Switzerland.<br /><searchLink fieldCode="AU" term="%22Forkuo+AD%22">Forkuo AD</searchLink>; Department of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana.<br /><searchLink fieldCode="AU" term="%22Gbedema+SY%22">Gbedema SY</searchLink>; Department of Pharmaceutics, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana.<br /><searchLink fieldCode="AU" term="%22Abdelall+S%22">Abdelall S</searchLink>; School of Pharmacy and Medical Sciences, University of Bradford, Bradford, UK.<br /><searchLink fieldCode="AU" term="%22Wahajuddin+M%22">Wahajuddin M</searchLink>; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, University of Bradford, Bradford, UK.<br /><searchLink fieldCode="AU" term="%22Jones+HS%22">Jones HS</searchLink>; Institute of Cancer Therapeutics, School of Pharmacy and Medical Sciences, University of Bradford, Bradford, UK.<br /><searchLink fieldCode="AU" term="%22Wright+CW%22">Wright CW</searchLink>; School of Pharmacy and Medical Sciences, University of Bradford, Bradford, UK.
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              Text: 2026 Apr
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