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Plasma chondroitin sulfate predicts the effectiveness of fluid resuscitation strategies in patients with sepsis.

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Title: Plasma chondroitin sulfate predicts the effectiveness of fluid resuscitation strategies in patients with sepsis.
Authors: Oshima K; Department of Medicine, Mass General Brigham, Boston, Massachusetts, USA., Yan B; Department of Biostatistics and., Tao R; Department of Biostatistics and.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Amorim G; Department of Biostatistics and., Di Gravio C; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom., McMurtry SA; Department of Medicine, University of Colorado, Aurora, Colorado, USA., Burke RC; Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA., Nam Y; Department of Biostatistics and., Nikolli I; Department of Medicine, Mass General Brigham, Boston, Massachusetts, USA., Kravitz MS; Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA., Stephenson D; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado, USA., Issaian A; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado, USA., Hansen KC; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado, USA., D'Alessandro A; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado, USA., Douglas IS; Department of Medicine, University of Colorado, Aurora, Colorado, USA.; Department of Medicine, Denver Health Medical Center, Denver, Colorado, USA., Self WH; Vanderbilt Institute for Clinical and Translational Research and Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Lindsell CJ; Department of Biostatistics and Bioinformatics and Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA., Leroux C; Department of Medicine, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, California, USA., Ringor A; Department of Medicine, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, California, USA., Matthay MA; Department of Medicine, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, California, USA., Schildcrout JS; Department of Biostatistics and., Shapiro NI; Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA., Schmidt EP; Department of Medicine, Mass General Brigham, Boston, Massachusetts, USA.
Source: The Journal of clinical investigation [J Clin Invest] 2026 Feb 03; Vol. 136 (7). Date of Electronic Publication: 2026 Feb 03 (Print Publication: 2026).
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Plasma chondroitin sulfate predicts the effectiveness of fluid resuscitation strategies in patients with sepsis.
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  Data: <searchLink fieldCode="AU" term="%22Oshima+K%22">Oshima K</searchLink>; Department of Medicine, Mass General Brigham, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Yan+B%22">Yan B</searchLink>; Department of Biostatistics and.<br /><searchLink fieldCode="AU" term="%22Tao+R%22">Tao R</searchLink>; Department of Biostatistics and.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Amorim+G%22">Amorim G</searchLink>; Department of Biostatistics and.<br /><searchLink fieldCode="AU" term="%22Di+Gravio+C%22">Di Gravio C</searchLink>; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22McMurtry+SA%22">McMurtry SA</searchLink>; Department of Medicine, University of Colorado, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Burke+RC%22">Burke RC</searchLink>; Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Nam+Y%22">Nam Y</searchLink>; Department of Biostatistics and.<br /><searchLink fieldCode="AU" term="%22Nikolli+I%22">Nikolli I</searchLink>; Department of Medicine, Mass General Brigham, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Kravitz+MS%22">Kravitz MS</searchLink>; Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Stephenson+D%22">Stephenson D</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Issaian+A%22">Issaian A</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Hansen+KC%22">Hansen KC</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22D'Alessandro+A%22">D'Alessandro A</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Douglas+IS%22">Douglas IS</searchLink>; Department of Medicine, University of Colorado, Aurora, Colorado, USA.; Department of Medicine, Denver Health Medical Center, Denver, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Self+WH%22">Self WH</searchLink>; Vanderbilt Institute for Clinical and Translational Research and Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Lindsell+CJ%22">Lindsell CJ</searchLink>; Department of Biostatistics and Bioinformatics and Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Leroux+C%22">Leroux C</searchLink>; Department of Medicine, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Ringor+A%22">Ringor A</searchLink>; Department of Medicine, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Matthay+MA%22">Matthay MA</searchLink>; Department of Medicine, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Schildcrout+JS%22">Schildcrout JS</searchLink>; Department of Biostatistics and.<br /><searchLink fieldCode="AU" term="%22Shapiro+NI%22">Shapiro NI</searchLink>; Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Schmidt+EP%22">Schmidt EP</searchLink>; Department of Medicine, Mass General Brigham, Boston, Massachusetts, USA.
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  Data: <searchLink fieldCode="JN" term="%227802877%22">The Journal of clinical investigation</searchLink> [J Clin Invest] 2026 Feb 03; Vol. 136 (7). <i>Date of Electronic Publication: </i>2026 Feb 03 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Clinical+Investigation%22">American Society for Clinical Investigation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7802877 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1558-8238 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219738%22">00219738 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Invest <i>Subsets: </i>MEDLINE
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