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Decoding cytokine networks in ulcerative colitis to identify pathogenic mechanisms and therapeutic targets.

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Title: Decoding cytokine networks in ulcerative colitis to identify pathogenic mechanisms and therapeutic targets.
Authors: Olbei M; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK., Hautefort I; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK.; Earlham Institute, Norwich NR4 7UZ, UK.; Quadram Institute, Norwich NR4 7UZ, UK.; NIHR Imperial BRC Organoid Facility, Imperial College London, London W12 0NN, UK., Thomas JP; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK.; UKRI MRC Laboratory of Medical Sciences, Hammersmith Hospital Campus, London W12 0NN, UK., Csabai L; Department of Genetics, Eotvos Lorand University, Budapest 1117, Hungary., Bohar B; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK., Koigi SS; NIHR Imperial BRC Organoid Facility, Imperial College London, London W12 0NN, UK., Ibraheim H; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK., Saifuddin A; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK., Coman D; Centre for Host Microbiome Interactions, King's College London, London WC2R 2LS, UK., Højmose Kromann E; Centre for Host Microbiome Interactions, King's College London, London WC2R 2LS, UK., Neves JF; Centre for Host Microbiome Interactions, King's College London, London WC2R 2LS, UK., Papp D; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK.; NIHR Imperial BRC Organoid Facility, Imperial College London, London W12 0NN, UK., Powell N; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK., Modos D; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK.; Quadram Institute, Norwich NR4 7UZ, UK., Korcsmaros T; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK.; Earlham Institute, Norwich NR4 7UZ, UK.; Quadram Institute, Norwich NR4 7UZ, UK.; NIHR Imperial BRC Organoid Facility, Imperial College London, London W12 0NN, UK.
Source: Science signaling [Sci Signal] 2026 Feb 03; Vol. 19 (923), pp. eadt0986. Date of Electronic Publication: 2026 Feb 03.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Decoding cytokine networks in ulcerative colitis to identify pathogenic mechanisms and therapeutic targets.
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  Data: <searchLink fieldCode="AU" term="%22Olbei+M%22">Olbei M</searchLink>; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Hautefort+I%22">Hautefort I</searchLink>; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK.; Earlham Institute, Norwich NR4 7UZ, UK.; Quadram Institute, Norwich NR4 7UZ, UK.; NIHR Imperial BRC Organoid Facility, Imperial College London, London W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Thomas+JP%22">Thomas JP</searchLink>; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK.; UKRI MRC Laboratory of Medical Sciences, Hammersmith Hospital Campus, London W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Csabai+L%22">Csabai L</searchLink>; Department of Genetics, Eotvos Lorand University, Budapest 1117, Hungary.<br /><searchLink fieldCode="AU" term="%22Bohar+B%22">Bohar B</searchLink>; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Koigi+SS%22">Koigi SS</searchLink>; NIHR Imperial BRC Organoid Facility, Imperial College London, London W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Ibraheim+H%22">Ibraheim H</searchLink>; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Saifuddin+A%22">Saifuddin A</searchLink>; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Coman+D%22">Coman D</searchLink>; Centre for Host Microbiome Interactions, King's College London, London WC2R 2LS, UK.<br /><searchLink fieldCode="AU" term="%22Højmose+Kromann+E%22">Højmose Kromann E</searchLink>; Centre for Host Microbiome Interactions, King's College London, London WC2R 2LS, UK.<br /><searchLink fieldCode="AU" term="%22Neves+JF%22">Neves JF</searchLink>; Centre for Host Microbiome Interactions, King's College London, London WC2R 2LS, UK.<br /><searchLink fieldCode="AU" term="%22Papp+D%22">Papp D</searchLink>; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK.; NIHR Imperial BRC Organoid Facility, Imperial College London, London W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Powell+N%22">Powell N</searchLink>; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Modos+D%22">Modos D</searchLink>; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK.; Quadram Institute, Norwich NR4 7UZ, UK.<br /><searchLink fieldCode="AU" term="%22Korcsmaros+T%22">Korcsmaros T</searchLink>; Department of Metabolism, Digestion, and Reproduction, Imperial College London, London W12 0NN, UK.; Earlham Institute, Norwich NR4 7UZ, UK.; Quadram Institute, Norwich NR4 7UZ, UK.; NIHR Imperial BRC Organoid Facility, Imperial College London, London W12 0NN, UK.
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  Data: <searchLink fieldCode="JN" term="%22101465400%22">Science signaling</searchLink> [Sci Signal] 2026 Feb 03; Vol. 19 (923), pp. eadt0986. <i>Date of Electronic Publication: </i>2026 Feb 03.
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              Text: 2026 Feb 03
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