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Introducing an In Vivo Protocol to Evaluate Skin Penetration of Topical Drugs: Proof-of-Concept with Naproxen in Humans.

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Title: Introducing an In Vivo Protocol to Evaluate Skin Penetration of Topical Drugs: Proof-of-Concept with Naproxen in Humans.
Authors: Ruiz-Ruiz MC; Departamento de Farmacología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Mexico City, Mexico., González-Flores ML; Departamento de Farmacología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Mexico City, Mexico., Vázquez-Román R; Dermatologist, Private practice, Mexico City, Mexico., Jiménez-Andrade JM; Unidad Académica Multidisciplinaria Reynosa-Aztlán, Universidad Autónoma de Tamaulipas, Reynosa, Tamaulipas, Mexico., Cabrera-Fuentes HA; División de Estudios de Posgrado e Investigación, Tecnológico Nacional de México / Instituto Tecnológico de Tijuana, Tijuana, B.C, Mexico; R&D Group, Vice presidency for Scientific Research and Innovation, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia., Castañeda-Hernández G; Departamento de Farmacología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Mexico City, Mexico. Electronic address: gcastane@cinvestav.mx.
Source: Archives of medical research [Arch Med Res] 2026 Jun; Vol. 57 (4), pp. 103388. Date of Electronic Publication: 2026 Feb 02.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 9312706 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5487 (Electronic) Linking ISSN: 01884409 NLM ISO Abbreviation: Arch Med Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Ruiz-Ruiz+MC%22">Ruiz-Ruiz MC</searchLink>; Departamento de Farmacología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22González-Flores+ML%22">González-Flores ML</searchLink>; Departamento de Farmacología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Vázquez-Román+R%22">Vázquez-Román R</searchLink>; Dermatologist, Private practice, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Jiménez-Andrade+JM%22">Jiménez-Andrade JM</searchLink>; Unidad Académica Multidisciplinaria Reynosa-Aztlán, Universidad Autónoma de Tamaulipas, Reynosa, Tamaulipas, Mexico.<br /><searchLink fieldCode="AU" term="%22Cabrera-Fuentes+HA%22">Cabrera-Fuentes HA</searchLink>; División de Estudios de Posgrado e Investigación, Tecnológico Nacional de México / Instituto Tecnológico de Tijuana, Tijuana, B.C, Mexico; R&D Group, Vice presidency for Scientific Research and Innovation, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Castañeda-Hernández+G%22">Castañeda-Hernández G</searchLink>; Departamento de Farmacología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Mexico City, Mexico. Electronic address: gcastane@cinvestav.mx.
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      – TitleFull: Introducing an In Vivo Protocol to Evaluate Skin Penetration of Topical Drugs: Proof-of-Concept with Naproxen in Humans.
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              Text: 2026 Jun
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