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HCMV infection disrupts barrier functions and promotes epithelial-mesenchymal transition in a cholangiocyte organoid model.

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Title: HCMV infection disrupts barrier functions and promotes epithelial-mesenchymal transition in a cholangiocyte organoid model.
Authors: Ye Z; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong SAR, China., Hu X; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong SAR, China., Rahaman SM; Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, Hong Kong SAR, China., Zheng Y; Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, Hong Kong SAR, China.; The 2nd Department of General Surgery, Shenzhen Children's Hospital, Shenzhen, Guangdong, China., Zhang X; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong SAR, China., Tang CSM; Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, Hong Kong SAR, China., Yau TM; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong SAR, China., Lee WK; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong SAR, China., Chung PHY; Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, Hong Kong SAR, China., Wong KKY; Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, Hong Kong SAR, China., Tam PKH; Faculty of Medicine, Macau University of Science and Technology, Coloane, Macau SAR, China., Lui VCH; Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, Hong Kong SAR, China. vchlui@hku.edu.hk., Cheung AKL; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong SAR, China. akcheung@hkbu.edu.hk.
Source: Nature communications [Nat Commun] 2026 Feb 03; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: HCMV infection disrupts barrier functions and promotes epithelial-mesenchymal transition in a cholangiocyte organoid model.
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  Data: <searchLink fieldCode="AU" term="%22Ye+Z%22">Ye Z</searchLink>; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Hu+X%22">Hu X</searchLink>; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Rahaman+SM%22">Rahaman SM</searchLink>; Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Zheng+Y%22">Zheng Y</searchLink>; Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, Hong Kong SAR, China.; The 2nd Department of General Surgery, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Tang+CSM%22">Tang CSM</searchLink>; Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Yau+TM%22">Yau TM</searchLink>; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Lee+WK%22">Lee WK</searchLink>; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Chung+PHY%22">Chung PHY</searchLink>; Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Wong+KKY%22">Wong KKY</searchLink>; Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Tam+PKH%22">Tam PKH</searchLink>; Faculty of Medicine, Macau University of Science and Technology, Coloane, Macau SAR, China.<br /><searchLink fieldCode="AU" term="%22Lui+VCH%22">Lui VCH</searchLink>; Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, Hong Kong SAR, China. vchlui@hku.edu.hk.<br /><searchLink fieldCode="AU" term="%22Cheung+AKL%22">Cheung AKL</searchLink>; Department of Biology, Faculty of Science, Hong Kong Baptist University, Kowloon Tong, Kowloon, Hong Kong SAR, China. akcheung@hkbu.edu.hk.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 Feb 03; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Feb 03.
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