A computational framework for sensitive tumor detection and accurate subtyping using shallow cell-free DNA methylome sequencing.
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| Title: | A computational framework for sensitive tumor detection and accurate subtyping using shallow cell-free DNA methylome sequencing. |
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| Authors: | Paoli M; Department of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy.; Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy., Galardi F; Translational Research Unit, Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy., Nardone A; Translational Research Unit, Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy., Biagioni C; Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy., Romagnoli D; Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy.; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy., Di Donato S; Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy., Franceschini GM; Department of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy., Livraghi L; Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy., Pestrin M; Medical Oncology Unit, Azienda Sanitaria Universitaria Giuliano Isontina, Gorizia, Italy., Sanna G; Medical Oncology, Ospedale Civile SS Annunziata, Sassari, Italy., Risi E; Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy., Migliaccio I; Translational Research Unit, Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy., Moretti E; Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy., Malorni L; Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy.; Translational Research Unit, Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy., Biganzoli L; Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy., Demichelis F; Department of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy., Benelli M; Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy. matteo.benelli@unifi.it.; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy. matteo.benelli@unifi.it. |
| Source: | Genome medicine [Genome Med] 2026 Feb 03; Vol. 18 (1). Date of Electronic Publication: 2026 Feb 03. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X (Electronic) Linking ISSN: 1756994X NLM ISO Abbreviation: Genome Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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