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Case Report: Personalized management of HER2-positive breast cancer with advanced nodal disease during pregnancy: a clinical case and review.

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Title: Case Report: Personalized management of HER2-positive breast cancer with advanced nodal disease during pregnancy: a clinical case and review.
Authors: Gullotta C; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Cancer Institute and Blood Diseases, Hospital Clinic de Barcelona, Barcelona, Spain.; Department of Oncology, Fondazione Policlinico Universitario Campus Bio-Medico di Roma, Rome, Italy., Walbaum B; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Cancer Institute and Blood Diseases, Hospital Clinic de Barcelona, Barcelona, Spain.; Department of Hematology Oncology, Pontificia Universidad Católica de Chile, Santiago, Chile.; Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain., Seguí E; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Cancer Institute and Blood Diseases, Hospital Clinic de Barcelona, Barcelona, Spain.; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, United States.; Breast Oncology Program, Dana-Farber Cancer Institute, Boston, MA, United States., López M; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Department of Obstetrics and Gynecology and Neonatology, Hospital Clinic of Barcelona, Barcelona, Spain., Mension E; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Department of Obstetrics and Gynecology and Neonatology, Hospital Clinic of Barcelona, Barcelona, Spain., Cebrecos I; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Department of Obstetrics and Gynecology and Neonatology, Hospital Clinic of Barcelona, Barcelona, Spain., Molla M; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Radiation Oncology Department, Hospital Clinic Barcelona, Barcelona, Spain., Oses G; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Radiation Oncology Department, Hospital Clinic Barcelona, Barcelona, Spain., Bargalló X; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Department of Radiology, Hospital Clinic, Barcelona, Spain., Ganau-Macias S; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Department of Radiology, Hospital Clinic, Barcelona, Spain., Sanfeliu E; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Pathology Department, Hospital Clínic de Barcelona, Barcelona, Spain., Braso-Maristany F; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Cancer Institute and Blood Diseases, Hospital Clinic de Barcelona, Barcelona, Spain.; Molecular Biology CORE (CDB), Hospital Clínic de Barcelona, Barcelona, Spain., Muñoz M; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Cancer Institute and Blood Diseases, Hospital Clinic de Barcelona, Barcelona, Spain.; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain., Prat A; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Cancer Institute and Blood Diseases, Hospital Clinic de Barcelona, Barcelona, Spain.; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Reveal Genomics, Barcelona, Spain.; Institute of Oncology (IOB), Hospital Quironsalud, Barcelona, Spain., Vidal M; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Cancer Institute and Blood Diseases, Hospital Clinic de Barcelona, Barcelona, Spain.; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Institute of Oncology (IOB), Hospital Quironsalud, Barcelona, Spain., Adamo B; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Cancer Institute and Blood Diseases, Hospital Clinic de Barcelona, Barcelona, Spain.; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.
Source: Frontiers in oncology [Front Oncol] 2026 Jan 19; Vol. 15, pp. 1672751. Date of Electronic Publication: 2026 Jan 19 (Print Publication: 2025).
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Case Report: Personalized management of HER2-positive breast cancer with advanced nodal disease during pregnancy: a clinical case and review.
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  Data: <searchLink fieldCode="AU" term="%22Gullotta+C%22">Gullotta C</searchLink>; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Cancer Institute and Blood Diseases, Hospital Clinic de Barcelona, Barcelona, Spain.; Department of Oncology, Fondazione Policlinico Universitario Campus Bio-Medico di Roma, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Walbaum+B%22">Walbaum B</searchLink>; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Cancer Institute and Blood Diseases, Hospital Clinic de Barcelona, Barcelona, Spain.; Department of Hematology Oncology, Pontificia Universidad Católica de Chile, Santiago, Chile.; Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Seguí+E%22">Seguí E</searchLink>; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Cancer Institute and Blood Diseases, Hospital Clinic de Barcelona, Barcelona, Spain.; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, United States.; Breast Oncology Program, Dana-Farber Cancer Institute, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22López+M%22">López M</searchLink>; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Department of Obstetrics and Gynecology and Neonatology, Hospital Clinic of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Mension+E%22">Mension E</searchLink>; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Department of Obstetrics and Gynecology and Neonatology, Hospital Clinic of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Cebrecos+I%22">Cebrecos I</searchLink>; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Department of Obstetrics and Gynecology and Neonatology, Hospital Clinic of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Molla+M%22">Molla M</searchLink>; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Radiation Oncology Department, Hospital Clinic Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Oses+G%22">Oses G</searchLink>; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Radiation Oncology Department, Hospital Clinic Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Bargalló+X%22">Bargalló X</searchLink>; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Department of Radiology, Hospital Clinic, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Ganau-Macias+S%22">Ganau-Macias S</searchLink>; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Department of Radiology, Hospital Clinic, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Sanfeliu+E%22">Sanfeliu E</searchLink>; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Pathology Department, Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Braso-Maristany+F%22">Braso-Maristany F</searchLink>; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Cancer Institute and Blood Diseases, Hospital Clinic de Barcelona, Barcelona, Spain.; Molecular Biology CORE (CDB), Hospital Clínic de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Muñoz+M%22">Muñoz M</searchLink>; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Cancer Institute and Blood Diseases, Hospital Clinic de Barcelona, Barcelona, Spain.; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Prat+A%22">Prat A</searchLink>; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Cancer Institute and Blood Diseases, Hospital Clinic de Barcelona, Barcelona, Spain.; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Reveal Genomics, Barcelona, Spain.; Institute of Oncology (IOB), Hospital Quironsalud, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Vidal+M%22">Vidal M</searchLink>; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Cancer Institute and Blood Diseases, Hospital Clinic de Barcelona, Barcelona, Spain.; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.; Institute of Oncology (IOB), Hospital Quironsalud, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Adamo+B%22">Adamo B</searchLink>; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain.; Cancer Institute and Blood Diseases, Hospital Clinic de Barcelona, Barcelona, Spain.; Facultat de Medicina i Ciencias de la Salut, Universitat de Barcelona (UB), Barcelona, Spain.
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