Oxyprenyl-chalcones as antibacterial hits: design of experiments-optimized synthesis, antibacterial evaluation, early drug-like profiling and biodegradability prediction.
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| Title: | Oxyprenyl-chalcones as antibacterial hits: design of experiments-optimized synthesis, antibacterial evaluation, early drug-like profiling and biodegradability prediction. |
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| Authors: | Marotta L; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it., Giammarino FMPR; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it., Senenou Tambou BB; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it., Tudino V; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it., Butini S; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it., Broccardo L; S-IN Soluzioni Informatiche srl. Italy., Cancade SMI; Department of Medical Biotechnologies, University of Siena Viale Bracci 16 53100 Siena Italy., Docquier JD; Department of Medical Biotechnologies, University of Siena Viale Bracci 16 53100 Siena Italy., Perego F; Department of Biomedical, Surgical and Dental Sciences, University of Milan Via Pascal 36 20133 Milan Italy., Basilico N; Department of Biomedical, Surgical and Dental Sciences, University of Milan Via Pascal 36 20133 Milan Italy., Raffellini L; Department of Pharmacy, University of Pisa Via Bonanno 6 Pisa 56126 Italy., Gul S; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Discovery Research ScreeningPort Schnackenburgallee 114 Hamburg 22525 Germany., Carullo G; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it., Gemma S; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it., Campiani G; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it. |
| Source: | RSC medicinal chemistry [RSC Med Chem] 2026 Jan 12. Date of Electronic Publication: 2026 Jan 12. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101759460 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2632-8682 (Electronic) Linking ISSN: 26328682 NLM ISO Abbreviation: RSC Med Chem |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41635702 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Oxyprenyl-chalcones as antibacterial hits: design of experiments-optimized synthesis, antibacterial evaluation, early drug-like profiling and biodegradability prediction. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Marotta+L%22">Marotta L</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it.<br /><searchLink fieldCode="AU" term="%22Giammarino+FMPR%22">Giammarino FMPR</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it.<br /><searchLink fieldCode="AU" term="%22Senenou+Tambou+BB%22">Senenou Tambou BB</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it.<br /><searchLink fieldCode="AU" term="%22Tudino+V%22">Tudino V</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it.<br /><searchLink fieldCode="AU" term="%22Butini+S%22">Butini S</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it.<br /><searchLink fieldCode="AU" term="%22Broccardo+L%22">Broccardo L</searchLink>; S-IN Soluzioni Informatiche srl. Italy.<br /><searchLink fieldCode="AU" term="%22Cancade+SMI%22">Cancade SMI</searchLink>; Department of Medical Biotechnologies, University of Siena Viale Bracci 16 53100 Siena Italy.<br /><searchLink fieldCode="AU" term="%22Docquier+JD%22">Docquier JD</searchLink>; Department of Medical Biotechnologies, University of Siena Viale Bracci 16 53100 Siena Italy.<br /><searchLink fieldCode="AU" term="%22Perego+F%22">Perego F</searchLink>; Department of Biomedical, Surgical and Dental Sciences, University of Milan Via Pascal 36 20133 Milan Italy.<br /><searchLink fieldCode="AU" term="%22Basilico+N%22">Basilico N</searchLink>; Department of Biomedical, Surgical and Dental Sciences, University of Milan Via Pascal 36 20133 Milan Italy.<br /><searchLink fieldCode="AU" term="%22Raffellini+L%22">Raffellini L</searchLink>; Department of Pharmacy, University of Pisa Via Bonanno 6 Pisa 56126 Italy.<br /><searchLink fieldCode="AU" term="%22Gul+S%22">Gul S</searchLink>; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Discovery Research ScreeningPort Schnackenburgallee 114 Hamburg 22525 Germany.<br /><searchLink fieldCode="AU" term="%22Carullo+G%22">Carullo G</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it.<br /><searchLink fieldCode="AU" term="%22Gemma+S%22">Gemma S</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it.<br /><searchLink fieldCode="AU" term="%22Campiani+G%22">Campiani G</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101759460%22">RSC medicinal chemistry</searchLink> [RSC Med Chem] 2026 Jan 12. <i>Date of Electronic Publication: </i>2026 Jan 12. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Royal+Society+of+Chemistry%22">Royal Society of Chemistry </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101759460 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2632-8682 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226328682%22">26328682 </searchLink><i>NLM ISO Abbreviation: </i>RSC Med Chem |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41635702 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1039/d5md00839e Languages: – Code: eng Text: English Titles: – TitleFull: Oxyprenyl-chalcones as antibacterial hits: design of experiments-optimized synthesis, antibacterial evaluation, early drug-like profiling and biodegradability prediction. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Marotta L – PersonEntity: Name: NameFull: Giammarino FMPR – PersonEntity: Name: NameFull: Senenou Tambou BB – PersonEntity: Name: NameFull: Tudino V – PersonEntity: Name: NameFull: Butini S – PersonEntity: Name: NameFull: Broccardo L – PersonEntity: Name: NameFull: Cancade SMI – PersonEntity: Name: NameFull: Docquier JD – PersonEntity: Name: NameFull: Perego F – PersonEntity: Name: NameFull: Basilico N – PersonEntity: Name: NameFull: Raffellini L – PersonEntity: Name: NameFull: Gul S – PersonEntity: Name: NameFull: Carullo G – PersonEntity: Name: NameFull: Gemma S – PersonEntity: Name: NameFull: Campiani G IsPartOfRelationships: – BibEntity: Dates: – D: 12 M: 01 Text: 2026 Jan 12 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2632-8682 Titles: – TitleFull: RSC medicinal chemistry Type: main |
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