Oxyprenyl-chalcones as antibacterial hits: design of experiments-optimized synthesis, antibacterial evaluation, early drug-like profiling and biodegradability prediction.
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| Title: | Oxyprenyl-chalcones as antibacterial hits: design of experiments-optimized synthesis, antibacterial evaluation, early drug-like profiling and biodegradability prediction. |
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| Authors: | Marotta L; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it., Giammarino FMPR; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it., Senenou Tambou BB; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it., Tudino V; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it., Butini S; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it., Broccardo L; S-IN Soluzioni Informatiche srl. Italy., Cancade SMI; Department of Medical Biotechnologies, University of Siena Viale Bracci 16 53100 Siena Italy., Docquier JD; Department of Medical Biotechnologies, University of Siena Viale Bracci 16 53100 Siena Italy., Perego F; Department of Biomedical, Surgical and Dental Sciences, University of Milan Via Pascal 36 20133 Milan Italy., Basilico N; Department of Biomedical, Surgical and Dental Sciences, University of Milan Via Pascal 36 20133 Milan Italy., Raffellini L; Department of Pharmacy, University of Pisa Via Bonanno 6 Pisa 56126 Italy., Gul S; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Discovery Research ScreeningPort Schnackenburgallee 114 Hamburg 22525 Germany., Carullo G; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it., Gemma S; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it., Campiani G; Department of Biotechnology, Chemistry and Pharmacy, University of Siena via Aldo Moro 2 53100 Siena Italy gemma@unisi.it. |
| Source: | RSC medicinal chemistry [RSC Med Chem] 2026 Jan 12. Date of Electronic Publication: 2026 Jan 12. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101759460 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2632-8682 (Electronic) Linking ISSN: 26328682 NLM ISO Abbreviation: RSC Med Chem |
| Database: | MEDLINE Ultimate |
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