Bevacizumab for Metastatic Colorectal Cancer with Chromosomal Instability: Cost-Effectiveness Analysis for a Novel Precision Treatment Approach in Germany, Ireland and Spain.

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Title: Bevacizumab for Metastatic Colorectal Cancer with Chromosomal Instability: Cost-Effectiveness Analysis for a Novel Precision Treatment Approach in Germany, Ireland and Spain.
Authors: Briody J; Data Science Centre, School of Population Health, RCSI University of Medicine and Health Sciences, Beaux Lane House, Lower Mercer St, Dublin 2, Ireland. jonathanbriody@rcsi.ie., Miller IS; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland., O'Mahony JF; School of Economics, University College Dublin, Dublin, Ireland.; Department of Public Health, Erasmus Medical Center, Rotterdam, The Netherlands., Tilson L; St James Hospital, National Centre for Pharmacoeconomics, Dublin, Ireland., O'Farrell AC; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland., Chen Q; The Pennsylvania State University Libraries, Penn State Abington, Abington, PA, USA., Murphy V; Cancer Trials Ireland, Dublin, Ireland., Casey O; Cancer Trials Ireland, Dublin, Ireland., Schulte N; Department of Medicine II, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany., Ebert MP; Department of Medicine II, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany., Prehn JHM; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland., Lambrechts D; Department of Human Genetics, Laboratory for Translational Genetics, VIB Center for Cancer Biology, Katholieke Universiteit Leuven, 3000, Leuven, Belgium., Ylstra B; Department of Pathology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Dienstmann R; Oncology Data Science (ODysSey) Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.; University of Vic-Central University of Catalonia, Vic, Spain., Byrne AT; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland., Bennett K; Data Science Centre, School of Population Health, RCSI University of Medicine and Health Sciences, Beaux Lane House, Lower Mercer St, Dublin 2, Ireland.
Source: PharmacoEconomics [Pharmacoeconomics] 2026 Mar; Vol. 44 (3), pp. 359-374. Date of Electronic Publication: 2026 Feb 04.
Publication Type: Journal Article
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9212404 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-2027 (Electronic) Linking ISSN: 11707690 NLM ISO Abbreviation: Pharmacoeconomics Subsets: MEDLINE
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  Data: Bevacizumab for Metastatic Colorectal Cancer with Chromosomal Instability: Cost-Effectiveness Analysis for a Novel Precision Treatment Approach in Germany, Ireland and Spain.
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  Data: <searchLink fieldCode="AU" term="%22Briody+J%22">Briody J</searchLink>; Data Science Centre, School of Population Health, RCSI University of Medicine and Health Sciences, Beaux Lane House, Lower Mercer St, Dublin 2, Ireland. jonathanbriody@rcsi.ie.<br /><searchLink fieldCode="AU" term="%22Miller+IS%22">Miller IS</searchLink>; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22O'Mahony+JF%22">O'Mahony JF</searchLink>; School of Economics, University College Dublin, Dublin, Ireland.; Department of Public Health, Erasmus Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Tilson+L%22">Tilson L</searchLink>; St James Hospital, National Centre for Pharmacoeconomics, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22O'Farrell+AC%22">O'Farrell AC</searchLink>; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Chen+Q%22">Chen Q</searchLink>; The Pennsylvania State University Libraries, Penn State Abington, Abington, PA, USA.<br /><searchLink fieldCode="AU" term="%22Murphy+V%22">Murphy V</searchLink>; Cancer Trials Ireland, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Casey+O%22">Casey O</searchLink>; Cancer Trials Ireland, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Schulte+N%22">Schulte N</searchLink>; Department of Medicine II, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Ebert+MP%22">Ebert MP</searchLink>; Department of Medicine II, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Prehn+JHM%22">Prehn JHM</searchLink>; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Lambrechts+D%22">Lambrechts D</searchLink>; Department of Human Genetics, Laboratory for Translational Genetics, VIB Center for Cancer Biology, Katholieke Universiteit Leuven, 3000, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Ylstra+B%22">Ylstra B</searchLink>; Department of Pathology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Dienstmann+R%22">Dienstmann R</searchLink>; Oncology Data Science (ODysSey) Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.; University of Vic-Central University of Catalonia, Vic, Spain.<br /><searchLink fieldCode="AU" term="%22Byrne+AT%22">Byrne AT</searchLink>; Department of Physiology and Medical Physics, RCSI University of Medicine and Health Sciences, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Bennett+K%22">Bennett K</searchLink>; Data Science Centre, School of Population Health, RCSI University of Medicine and Health Sciences, Beaux Lane House, Lower Mercer St, Dublin 2, Ireland.
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