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Overcoming host restrictions to enable continuous passaging of GII.3 human norovirus in human intestinal enteroids.

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Title: Overcoming host restrictions to enable continuous passaging of GII.3 human norovirus in human intestinal enteroids.
Authors: Kaur G; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA., Crawford SE; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA., Javornik Cregeen S; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX, USA., Surathu A; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX, USA., Ayyar BV; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA., Apostol CV; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX, USA., Phuc HN; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA., Ettayebi K; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA., Boussattach A; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA., Zeng XL; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA., Blutt SE; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.; Department of Medicine, Baylor College of Medicine, Houston, TX, USA., Doddapaneni H; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Muzny DM; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Coarfa C; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.; Department of Medicine, Baylor College of Medicine, Houston, TX, USA., Anish R; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX, USA., Prasad BVV; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX, USA., Atmar RL; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Ramani S; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA., Estes MK; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
Source: Science advances [Sci Adv] 2026 Feb 06; Vol. 12 (6), pp. eaeb0455. Date of Electronic Publication: 2026 Feb 04.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE
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