Cytoplasmic NAD/H synthesis via NRK1 regulates inflammatory capacity and promotes survival of CD4+ T cells.
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| Title: | Cytoplasmic NAD/H synthesis via NRK1 regulates inflammatory capacity and promotes survival of CD4+ T cells. |
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| Authors: | Stavrou V; Department of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, UK.; Department of Metabolism and Systems Science, College of Medicine and Health, University of Birmingham, Birmingham, UK., Ali M; Department of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, UK.; Department of Metabolism and Systems Science, College of Medicine and Health, University of Birmingham, Birmingham, UK., Gudgeon N; Department of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, UK.; Department of Metabolism and Systems Science, College of Medicine and Health, University of Birmingham, Birmingham, UK.; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Bishop EL; Department of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, UK.; Department of Metabolism and Systems Science, College of Medicine and Health, University of Birmingham, Birmingham, UK., Fulton-Ward T; Department of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, UK.; Department of Metabolism and Systems Science, College of Medicine and Health, University of Birmingham, Birmingham, UK., Turley B; Department of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, UK.; Department of Metabolism and Systems Science, College of Medicine and Health, University of Birmingham, Birmingham, UK., Heising S; Department of Metabolism and Systems Science, College of Medicine and Health, University of Birmingham, Birmingham, UK., Mohamed SH; Department of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, UK.; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Hain S; Department of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, UK.; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., George L; Department of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, UK.; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Deng M; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham, UK., McCowan J; Cancer Research UK Scotland Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, Scotland, UK., Sheriff L; Department of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, UK.; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Davies SP; Department of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, UK., Marzullo B; Department of Metabolism and Systems Science, College of Medicine and Health, University of Birmingham, Birmingham, UK., Tennant DA; Department of Metabolism and Systems Science, College of Medicine and Health, University of Birmingham, Birmingham, UK., Doig CL; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham, UK., Bending DA; Department of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, UK., Roberts EW; Cancer Research UK Scotland Institute, Glasgow, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, Scotland, UK., Lavery GG; Department of Biosciences, School of Science and Technology, Nottingham Trent University, Nottingham, UK., Drummond RA; Department of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, UK.; Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK., Dimeloe S; Department of Immunology and Immunotherapy, College of Medicine and Health, University of Birmingham, Birmingham, UK. s.k.dimeloe@bham.ac.uk.; Department of Metabolism and Systems Science, College of Medicine and Health, University of Birmingham, Birmingham, UK. s.k.dimeloe@bham.ac.uk. |
| Source: | Nature communications [Nat Commun] 2026 Feb 04; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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