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A split biotin ligase approach reveals proteins associated with oligomeric alpha-synuclein during aggregation.

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Title: A split biotin ligase approach reveals proteins associated with oligomeric alpha-synuclein during aggregation.
Authors: Fernandes AR; Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA.; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Owen AP; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Office for Non-Clinical Education Programs, Mayo Clinic, Jacksonville, FL, USA., Faroqi AH; Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA.; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Lee J; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Sachdeva GS; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.; Manipal Academy of Higher Education, Manipal, India., Morderer D; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Hoffmann C; Mayo Clinic Proteomics Core, Rochester, MN, USA., Madden B; Mayo Clinic Proteomics Core, Rochester, MN, USA., Zhang S; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Ren Y; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA., Boschen SL; Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA.; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Pandey A; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.; Manipal Academy of Higher Education, Manipal, India., Rossoll W; Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA.; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., McLean PJ; Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA. mclean.pamela@mayo.edu.; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. mclean.pamela@mayo.edu.
Source: Scientific reports [Sci Rep] 2026 Feb 04; Vol. 16 (1). Date of Electronic Publication: 2026 Feb 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Fernandes+AR%22">Fernandes AR</searchLink>; Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA.; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Owen+AP%22">Owen AP</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.; Office for Non-Clinical Education Programs, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Faroqi+AH%22">Faroqi AH</searchLink>; Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA.; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Sachdeva+GS%22">Sachdeva GS</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.; Manipal Academy of Higher Education, Manipal, India.<br /><searchLink fieldCode="AU" term="%22Morderer+D%22">Morderer D</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Hoffmann+C%22">Hoffmann C</searchLink>; Mayo Clinic Proteomics Core, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Madden+B%22">Madden B</searchLink>; Mayo Clinic Proteomics Core, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Ren+Y%22">Ren Y</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Boschen+SL%22">Boschen SL</searchLink>; Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA.; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Pandey+A%22">Pandey A</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.; Manipal Academy of Higher Education, Manipal, India.<br /><searchLink fieldCode="AU" term="%22Rossoll+W%22">Rossoll W</searchLink>; Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA.; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22McLean+PJ%22">McLean PJ</searchLink>; Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, FL, USA. mclean.pamela@mayo.edu.; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA. mclean.pamela@mayo.edu.
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