Hypocretin receptor 1 blockade early in abstinence prevents incubation of cocaine seeking and normalizes dopamine transmission.

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Title: Hypocretin receptor 1 blockade early in abstinence prevents incubation of cocaine seeking and normalizes dopamine transmission.
Authors: Clark PJ; Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA, 19129, USA., Migovich VM; Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA, 19129, USA., Das S; Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, 19129, USA., Xu W; Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, 19129, USA., Zhang Y; Research Triangle Institute, Research Triangle Park, P.O. Box 12255, Durham, NC, 27709, USA., Kortagere S; Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, 19129, USA., España RA; Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA, 19129, USA. rae39@drexel.edu.
Source: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2026 May; Vol. 51 (6), pp. 1123-1134. Date of Electronic Publication: 2026 Feb 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8904907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1740-634X (Electronic) Linking ISSN: 0893133X NLM ISO Abbreviation: Neuropsychopharmacology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1740-634X
DOI:10.1038/s41386-025-02315-9