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De novo protein design: a transformative frontier in clinical protein applications.

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Title: De novo protein design: a transformative frontier in clinical protein applications.
Authors: Gao J; Department of Cardiology, The Affiliated Hospital, Southwest Medical University, No. 1, Section 1, Xianglin Road, Luzhou, Sichuan, 646000, China.; Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China.; Basic Medicine Research Innovation Center for Cardiometabolic Diseases, Ministry of Education, Southwest Medical University, Luzhou, Sichuan, 646000, China.; Nucleic Acid Medicine of Luzhou Key Laboratory, Southwest Medical University, Luzhou, Sichuan, 646000, China., Zheng Z; Department of Cardiology, Panzhihua Central Hospital, Panzhihua, 617000, China.; Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China.; Nucleic Acid Medicine of Luzhou Key Laboratory, Southwest Medical University, Luzhou, Sichuan, 646000, China., Yu X; Chongqing University Jiangjin Hospital, Chongqing, 402260, China., Luo Y; School of Medical Information and Engineering, Southwest Medical University, Luzhou, Sichuan, 646000, China., Yu Y; Department of Cardiology, The Affiliated Hospital, Southwest Medical University, No. 1, Section 1, Xianglin Road, Luzhou, Sichuan, 646000, China. dr.yangyuself@gmail.com.; Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China. dr.yangyuself@gmail.com.; Basic Medicine Research Innovation Center for Cardiometabolic Diseases, Ministry of Education, Southwest Medical University, Luzhou, Sichuan, 646000, China. dr.yangyuself@gmail.com.; Nucleic Acid Medicine of Luzhou Key Laboratory, Southwest Medical University, Luzhou, Sichuan, 646000, China. dr.yangyuself@gmail.com., Zhang C; Department of Cardiology, The Affiliated Hospital, Southwest Medical University, No. 1, Section 1, Xianglin Road, Luzhou, Sichuan, 646000, China. zcxteam@163.com.; Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China. zcxteam@163.com.; Basic Medicine Research Innovation Center for Cardiometabolic Diseases, Ministry of Education, Southwest Medical University, Luzhou, Sichuan, 646000, China. zcxteam@163.com.; Nucleic Acid Medicine of Luzhou Key Laboratory, Southwest Medical University, Luzhou, Sichuan, 646000, China. zcxteam@163.com.
Source: Journal of translational medicine [J Transl Med] 2026 Feb 04; Vol. 24 (1). Date of Electronic Publication: 2026 Feb 04.
Publication Type: Journal Article; Review
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: De novo protein design: a transformative frontier in clinical protein applications.
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  Data: <searchLink fieldCode="AU" term="%22Gao+J%22">Gao J</searchLink>; Department of Cardiology, The Affiliated Hospital, Southwest Medical University, No. 1, Section 1, Xianglin Road, Luzhou, Sichuan, 646000, China.; Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China.; Basic Medicine Research Innovation Center for Cardiometabolic Diseases, Ministry of Education, Southwest Medical University, Luzhou, Sichuan, 646000, China.; Nucleic Acid Medicine of Luzhou Key Laboratory, Southwest Medical University, Luzhou, Sichuan, 646000, China.<br /><searchLink fieldCode="AU" term="%22Zheng+Z%22">Zheng Z</searchLink>; Department of Cardiology, Panzhihua Central Hospital, Panzhihua, 617000, China.; Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China.; Nucleic Acid Medicine of Luzhou Key Laboratory, Southwest Medical University, Luzhou, Sichuan, 646000, China.<br /><searchLink fieldCode="AU" term="%22Yu+X%22">Yu X</searchLink>; Chongqing University Jiangjin Hospital, Chongqing, 402260, China.<br /><searchLink fieldCode="AU" term="%22Luo+Y%22">Luo Y</searchLink>; School of Medical Information and Engineering, Southwest Medical University, Luzhou, Sichuan, 646000, China.<br /><searchLink fieldCode="AU" term="%22Yu+Y%22">Yu Y</searchLink>; Department of Cardiology, The Affiliated Hospital, Southwest Medical University, No. 1, Section 1, Xianglin Road, Luzhou, Sichuan, 646000, China. dr.yangyuself@gmail.com.; Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China. dr.yangyuself@gmail.com.; Basic Medicine Research Innovation Center for Cardiometabolic Diseases, Ministry of Education, Southwest Medical University, Luzhou, Sichuan, 646000, China. dr.yangyuself@gmail.com.; Nucleic Acid Medicine of Luzhou Key Laboratory, Southwest Medical University, Luzhou, Sichuan, 646000, China. dr.yangyuself@gmail.com.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Department of Cardiology, The Affiliated Hospital, Southwest Medical University, No. 1, Section 1, Xianglin Road, Luzhou, Sichuan, 646000, China. zcxteam@163.com.; Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan, 646000, China. zcxteam@163.com.; Basic Medicine Research Innovation Center for Cardiometabolic Diseases, Ministry of Education, Southwest Medical University, Luzhou, Sichuan, 646000, China. zcxteam@163.com.; Nucleic Acid Medicine of Luzhou Key Laboratory, Southwest Medical University, Luzhou, Sichuan, 646000, China. zcxteam@163.com.
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  Data: <searchLink fieldCode="JN" term="%22101190741%22">Journal of translational medicine</searchLink> [J Transl Med] 2026 Feb 04; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 Feb 04.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101190741 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1479-5876 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214795876%22">14795876 </searchLink><i>NLM ISO Abbreviation: </i>J Transl Med <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12967-026-07784-0
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              Text: 2026 Feb 04
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              Y: 2026
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