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Intensity-modulated proton therapy for patients with unresectable giant (≥ 10 cm) hepatocellular carcinoma: a retrospective analysis from two high-volume centers.

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Title: Intensity-modulated proton therapy for patients with unresectable giant (≥ 10 cm) hepatocellular carcinoma: a retrospective analysis from two high-volume centers.
Authors: Cheng JY; Department of Radiation Oncology & Proton and Radiation Therapy Center, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, No. 5, Fuxing St., Guishan Dist., Taoyuan City, 33305, Taiwan, ROC.; Center for General Education, Cheng Shiu University, Kaohsiung, Taiwan, ROC., Wang YM; Department of Radiation Oncology & Proton and Radiation Therapy Center, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, No. 5, Fuxing St., Guishan Dist., Taoyuan City, 33305, Taiwan, ROC.; School of Traditional Chinese, Chang Gung University, Taoyuan, Taiwan, ROC.; Department of Radiation Oncology, Kaohsiung Chang Gung Memorial Hospital, School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung, Taiwan, ROC., Chen YH; Division of Hematology-Oncology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan, ROC.; School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC., Liu CM; Department of Radiation Oncology & Proton and Radiation Therapy Center, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, No. 5, Fuxing St., Guishan Dist., Taoyuan City, 33305, Taiwan, ROC., Huang EY; Department of Radiation Oncology & Proton and Radiation Therapy Center, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, No. 5, Fuxing St., Guishan Dist., Taoyuan City, 33305, Taiwan, ROC.; School of Traditional Chinese, Chang Gung University, Taoyuan, Taiwan, ROC.; Department of Radiation Oncology, Kaohsiung Chang Gung Memorial Hospital, School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung, Taiwan, ROC., Ou HY; Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan, ROC., Hu TH; Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan, ROC., Lu SN; Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan, ROC., Wang CC; Division of General Surgery, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan, ROC., Tseng JH; Department of Medical Imaging and Intervention, Linkou Chang Gung Memorial Hospital and University, Taoyuan City, Taiwan, ROC., Lin SM; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Linkou Chang Gung Memorial Hospital and University, Taoyuan City, Taiwan, ROC., Lin CC; School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.; Department of Gastroenterology and Hepatology, New Taipei Municipal Tucheng Hospital (Built and Operated By Chang Gung Memorial Hospital), New Taipei, Taiwan, ROC., Chan KM; Department of General Surgery, Linkou Chang Gung Memorial Hospital and University, Taoyuan City, Taiwan, ROC., Chen WY; Department of Radiation Oncology, National Taiwan University Cancer Center, Taipei, Taiwan, ROC.; Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC.; Devision of Radiation Oncology, Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan., Huang BS; Department of Radiation Oncology & Proton and Radiation Therapy Center, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, No. 5, Fuxing St., Guishan Dist., Taoyuan City, 33305, Taiwan, ROC. beanson@cgmh.org.tw.; School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC. beanson@cgmh.org.tw.; Department of Radiation Oncology, Linkou Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan, ROC. beanson@cgmh.org.tw.
Source: Japanese journal of radiology [Jpn J Radiol] 2026 Jun; Vol. 44 (6), pp. 1085-1094. Date of Electronic Publication: 2026 Feb 05.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Springer Country of Publication: Japan NLM ID: 101490689 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1867-108X (Electronic) Linking ISSN: 18671071 NLM ISO Abbreviation: Jpn J Radiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Intensity-modulated proton therapy for patients with unresectable giant (≥ 10 cm) hepatocellular carcinoma: a retrospective analysis from two high-volume centers.
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  Data: <searchLink fieldCode="AU" term="%22Cheng+JY%22">Cheng JY</searchLink>; Department of Radiation Oncology & Proton and Radiation Therapy Center, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, No. 5, Fuxing St., Guishan Dist., Taoyuan City, 33305, Taiwan, ROC.; Center for General Education, Cheng Shiu University, Kaohsiung, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Wang+YM%22">Wang YM</searchLink>; Department of Radiation Oncology & Proton and Radiation Therapy Center, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, No. 5, Fuxing St., Guishan Dist., Taoyuan City, 33305, Taiwan, ROC.; School of Traditional Chinese, Chang Gung University, Taoyuan, Taiwan, ROC.; Department of Radiation Oncology, Kaohsiung Chang Gung Memorial Hospital, School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Chen+YH%22">Chen YH</searchLink>; Division of Hematology-Oncology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan, ROC.; School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Liu+CM%22">Liu CM</searchLink>; Department of Radiation Oncology & Proton and Radiation Therapy Center, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, No. 5, Fuxing St., Guishan Dist., Taoyuan City, 33305, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Huang+EY%22">Huang EY</searchLink>; Department of Radiation Oncology & Proton and Radiation Therapy Center, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, No. 5, Fuxing St., Guishan Dist., Taoyuan City, 33305, Taiwan, ROC.; School of Traditional Chinese, Chang Gung University, Taoyuan, Taiwan, ROC.; Department of Radiation Oncology, Kaohsiung Chang Gung Memorial Hospital, School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Ou+HY%22">Ou HY</searchLink>; Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Hu+TH%22">Hu TH</searchLink>; Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lu+SN%22">Lu SN</searchLink>; Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Wang+CC%22">Wang CC</searchLink>; Division of General Surgery, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Tseng+JH%22">Tseng JH</searchLink>; Department of Medical Imaging and Intervention, Linkou Chang Gung Memorial Hospital and University, Taoyuan City, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lin+SM%22">Lin SM</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Linkou Chang Gung Memorial Hospital and University, Taoyuan City, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lin+CC%22">Lin CC</searchLink>; School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.; Department of Gastroenterology and Hepatology, New Taipei Municipal Tucheng Hospital (Built and Operated By Chang Gung Memorial Hospital), New Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Chan+KM%22">Chan KM</searchLink>; Department of General Surgery, Linkou Chang Gung Memorial Hospital and University, Taoyuan City, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Chen+WY%22">Chen WY</searchLink>; Department of Radiation Oncology, National Taiwan University Cancer Center, Taipei, Taiwan, ROC.; Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan, ROC.; Devision of Radiation Oncology, Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+BS%22">Huang BS</searchLink>; Department of Radiation Oncology & Proton and Radiation Therapy Center, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, No. 5, Fuxing St., Guishan Dist., Taoyuan City, 33305, Taiwan, ROC. beanson@cgmh.org.tw.; School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC. beanson@cgmh.org.tw.; Department of Radiation Oncology, Linkou Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan, ROC. beanson@cgmh.org.tw.
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  Data: <searchLink fieldCode="JN" term="%22101490689%22">Japanese journal of radiology</searchLink> [Jpn J Radiol] 2026 Jun; Vol. 44 (6), pp. 1085-1094. <i>Date of Electronic Publication: </i>2026 Feb 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Japan <i>NLM ID: </i>101490689 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1867-108X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218671071%22">18671071 </searchLink><i>NLM ISO Abbreviation: </i>Jpn J Radiol <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s11604-026-01947-1
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      – Code: eng
        Text: English
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        StartPage: 1085
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      – TitleFull: Intensity-modulated proton therapy for patients with unresectable giant (≥ 10 cm) hepatocellular carcinoma: a retrospective analysis from two high-volume centers.
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              M: 06
              Text: 2026 Jun
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