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T cell receptors for antigen on intraepithelial cytolytic T lymphocytes in celiac disease engage enterocyte HLA-E and HLA-B.

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Title: T cell receptors for antigen on intraepithelial cytolytic T lymphocytes in celiac disease engage enterocyte HLA-E and HLA-B.
Authors: Johnson JE; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519., Agrawal K; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519.; Department of Pathology, Yale School of Medicine, New Haven, CT 06519., Al-Lamki RS; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519.; Department of Medicine, University of Cambridge, United Kingdom, Cambridge, CB20AH, United Kingdom., Zhang F; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519., Wang XD; Department of Medicine, University of Cambridge, United Kingdom, Cambridge, CB20AH, United Kingdom., Tobiasova Z; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519., Taleb SA; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519., Liburd S Jr; Department of Biomedical Engineering, Yale University, New Haven, CT 06511., Rodriguez L; Yale Pediatric Gastroenterology and Hepatology, Yale School of Medicine, New Haven, CT 06520., Martins AJ; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519., Flavell RA; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519.; HHMI, Yale School of Medicine, New Haven, CT 06519., Robert ME; Department of Pathology, Yale School of Medicine, New Haven, CT 06519., Sefik E; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519., Pober JS; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519.; Department of Pathology, Yale School of Medicine, New Haven, CT 06519.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Feb 10; Vol. 123 (6), pp. e2525433123. Date of Electronic Publication: 2026 Feb 05.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Johnson+JE%22">Johnson JE</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519.<br /><searchLink fieldCode="AU" term="%22Agrawal+K%22">Agrawal K</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519.; Department of Pathology, Yale School of Medicine, New Haven, CT 06519.<br /><searchLink fieldCode="AU" term="%22Al-Lamki+RS%22">Al-Lamki RS</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519.; Department of Medicine, University of Cambridge, United Kingdom, Cambridge, CB20AH, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Zhang+F%22">Zhang F</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519.<br /><searchLink fieldCode="AU" term="%22Wang+XD%22">Wang XD</searchLink>; Department of Medicine, University of Cambridge, United Kingdom, Cambridge, CB20AH, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Tobiasova+Z%22">Tobiasova Z</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519.<br /><searchLink fieldCode="AU" term="%22Taleb+SA%22">Taleb SA</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519.<br /><searchLink fieldCode="AU" term="%22Liburd+S+Jr%22">Liburd S Jr</searchLink>; Department of Biomedical Engineering, Yale University, New Haven, CT 06511.<br /><searchLink fieldCode="AU" term="%22Rodriguez+L%22">Rodriguez L</searchLink>; Yale Pediatric Gastroenterology and Hepatology, Yale School of Medicine, New Haven, CT 06520.<br /><searchLink fieldCode="AU" term="%22Martins+AJ%22">Martins AJ</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519.<br /><searchLink fieldCode="AU" term="%22Flavell+RA%22">Flavell RA</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519.; HHMI, Yale School of Medicine, New Haven, CT 06519.<br /><searchLink fieldCode="AU" term="%22Robert+ME%22">Robert ME</searchLink>; Department of Pathology, Yale School of Medicine, New Haven, CT 06519.<br /><searchLink fieldCode="AU" term="%22Sefik+E%22">Sefik E</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519.<br /><searchLink fieldCode="AU" term="%22Pober+JS%22">Pober JS</searchLink>; Department of Immunobiology, Yale School of Medicine, New Haven, CT 06519.; Department of Pathology, Yale School of Medicine, New Haven, CT 06519.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2026 Feb 10; Vol. 123 (6), pp. e2525433123. <i>Date of Electronic Publication: </i>2026 Feb 05.
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