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Bioengineered chimeric VLPs targeting chikungunya virus and SARS-CoV-2 show high immunogenicity in mice.

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Title: Bioengineered chimeric VLPs targeting chikungunya virus and SARS-CoV-2 show high immunogenicity in mice.
Authors: Singh VA; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India., Nehul S; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India., Saha A; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India., Singh V; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India., Bhutkar M; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India., Kumar CS; Kusuma School of Biological Sciences, Indian Institute of Technology - Delhi, Hauz Khas, New Delhi, 110016, India., Banerjee M; Kusuma School of Biological Sciences, Indian Institute of Technology - Delhi, Hauz Khas, New Delhi, 110016, India., Kuhn RJ; Department of Biological Sciences, Purdue University, West Lafayette, IN, 47907, USA., Kumar P; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India., Sharma GK; Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, 243122, India., Tomar S; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India. Electronic address: shailly.tomar@bt.iitr.ac.in.
Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2026 Mar 19; Vol. 805, pp. 153346. Date of Electronic Publication: 2026 Jan 23.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE
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  Data: Bioengineered chimeric VLPs targeting chikungunya virus and SARS-CoV-2 show high immunogenicity in mice.
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  Data: <searchLink fieldCode="AU" term="%22Singh+VA%22">Singh VA</searchLink>; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India.<br /><searchLink fieldCode="AU" term="%22Nehul+S%22">Nehul S</searchLink>; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India.<br /><searchLink fieldCode="AU" term="%22Saha+A%22">Saha A</searchLink>; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India.<br /><searchLink fieldCode="AU" term="%22Singh+V%22">Singh V</searchLink>; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India.<br /><searchLink fieldCode="AU" term="%22Bhutkar+M%22">Bhutkar M</searchLink>; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India.<br /><searchLink fieldCode="AU" term="%22Kumar+CS%22">Kumar CS</searchLink>; Kusuma School of Biological Sciences, Indian Institute of Technology - Delhi, Hauz Khas, New Delhi, 110016, India.<br /><searchLink fieldCode="AU" term="%22Banerjee+M%22">Banerjee M</searchLink>; Kusuma School of Biological Sciences, Indian Institute of Technology - Delhi, Hauz Khas, New Delhi, 110016, India.<br /><searchLink fieldCode="AU" term="%22Kuhn+RJ%22">Kuhn RJ</searchLink>; Department of Biological Sciences, Purdue University, West Lafayette, IN, 47907, USA.<br /><searchLink fieldCode="AU" term="%22Kumar+P%22">Kumar P</searchLink>; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India.<br /><searchLink fieldCode="AU" term="%22Sharma+GK%22">Sharma GK</searchLink>; Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, 243122, India.<br /><searchLink fieldCode="AU" term="%22Tomar+S%22">Tomar S</searchLink>; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India. Electronic address: shailly.tomar@bt.iitr.ac.in.
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  Data: <searchLink fieldCode="JN" term="%220372516%22">Biochemical and biophysical research communications</searchLink> [Biochem Biophys Res Commun] 2026 Mar 19; Vol. 805, pp. 153346. <i>Date of Electronic Publication: </i>2026 Jan 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0372516 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2104 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220006291X%22">0006291X </searchLink><i>NLM ISO Abbreviation: </i>Biochem Biophys Res Commun <i>Subsets: </i>MEDLINE
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              Text: 2026 Mar 19
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