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Protein-protein interactions are a major source of epistasis in genetic interaction networks.

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Title: Protein-protein interactions are a major source of epistasis in genetic interaction networks.
Authors: Castellanos-Girouard X; Department of Biochemistry, Université de Montréal, Montreal, QC, Canada.; Robert-Cedergren Center for Bioinformatics and Genomics, Université de Montréal, Montreal, QC, Canada.; Wellcome Sanger Institute, Cambridge, UK., Serohijos AWR; Department of Biochemistry, Université de Montréal, Montreal, QC, Canada. adrian.serohijos@umontreal.ca.; Robert-Cedergren Center for Bioinformatics and Genomics, Université de Montréal, Montreal, QC, Canada. adrian.serohijos@umontreal.ca., Michnick SW; Department of Biochemistry, Université de Montréal, Montreal, QC, Canada. stephen.michnick@umontreal.ca.; Robert-Cedergren Center for Bioinformatics and Genomics, Université de Montréal, Montreal, QC, Canada. stephen.michnick@umontreal.ca.
Source: Nature communications [Nat Commun] 2026 Feb 05; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 05.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Castellanos-Girouard+X%22">Castellanos-Girouard X</searchLink>; Department of Biochemistry, Université de Montréal, Montreal, QC, Canada.; Robert-Cedergren Center for Bioinformatics and Genomics, Université de Montréal, Montreal, QC, Canada.; Wellcome Sanger Institute, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Serohijos+AWR%22">Serohijos AWR</searchLink>; Department of Biochemistry, Université de Montréal, Montreal, QC, Canada. adrian.serohijos@umontreal.ca.; Robert-Cedergren Center for Bioinformatics and Genomics, Université de Montréal, Montreal, QC, Canada. adrian.serohijos@umontreal.ca.<br /><searchLink fieldCode="AU" term="%22Michnick+SW%22">Michnick SW</searchLink>; Department of Biochemistry, Université de Montréal, Montreal, QC, Canada. stephen.michnick@umontreal.ca.; Robert-Cedergren Center for Bioinformatics and Genomics, Université de Montréal, Montreal, QC, Canada. stephen.michnick@umontreal.ca.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 Feb 05; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Feb 05.
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        Value: 10.1038/s41467-026-69152-2
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              Text: 2026 Feb 05
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