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Feeding-regulated glycogen metabolism drives rhythmic liver protein secretion.

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Title: Feeding-regulated glycogen metabolism drives rhythmic liver protein secretion.
Authors: Weger M; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia., Mauvoisin D; Nestlé Research, Société des Produits Nestlé, Lausanne, Switzerland.; Nantes Université, CNRS, INSERM, l'institut du thorax, Nantes, France., Hoyle D; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia., Wang J; Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.; Institute of Molecular Biotechnology (IMBA), Austrian Academy of Sciences, Vienna Biocenter, Campus Vienna Biocenter, Vienna, Austria., Martin E; Nestlé Research, Société des Produits Nestlé, Lausanne, Switzerland.; Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland., Rae J; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia., Ferguson C; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia., Klinke G; Metabolomics Core Technology Platform, Center for Organismal Studies (COS), Heidelberg University, Heidelberg, Germany., Cielesh M; Charles Perkins Centre, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Macauslane KL; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, Queensland, Australia., Larance M; Charles Perkins Centre, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Quadroni M; Protein Analysis Facility, University of Lausanne, Lausanne, Switzerland., Templeman I; Centre for Nutrition, Exercise, and Metabolism, Department for Health, University of Bath, Bath, UK., Walhin JP; Centre for Nutrition, Exercise, and Metabolism, Department for Health, University of Bath, Bath, UK., Karagounis LG; Nestlé Research, Société des Produits Nestlé, Lausanne, Switzerland.; Department of Diabetes, Endocrinology, Nutritional Metabolism, and Metabolism, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.; Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Victoria, Australia., Betts JA; Centre for Nutrition, Exercise, and Metabolism, Department for Health, University of Bath, Bath, UK., Johnston JD; Section of Chronobiology, School of Biosciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK., Durussel F; Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland., Firsov D; Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland., Fournier S; Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.; Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland., Müller O; Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.; Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland., Schulz BL; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, Queensland, Australia., Parton RG; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia.; Centre for Microscopy and Microanalysis, The University of Queensland, St Lucia, Queensland, Australia., Weger BD; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia. b.weger@uq.edu.au.; Nestlé Research, Société des Produits Nestlé, Lausanne, Switzerland. b.weger@uq.edu.au., Gachon F; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia. frga@biomed.au.dk.; Nestlé Research, Société des Produits Nestlé, Lausanne, Switzerland. frga@biomed.au.dk.; Department of Biomedicine, Aarhus University, Aarhus, Denmark. frga@biomed.au.dk.; Steno Diabetes Center Aarhus, Aarhus, Denmark. frga@biomed.au.dk.
Source: Nature metabolism [Nat Metab] 2026 Feb; Vol. 8 (2), pp. 327-349. Date of Electronic Publication: 2026 Feb 05.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Weger+M%22">Weger M</searchLink>; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Mauvoisin+D%22">Mauvoisin D</searchLink>; Nestlé Research, Société des Produits Nestlé, Lausanne, Switzerland.; Nantes Université, CNRS, INSERM, l'institut du thorax, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Hoyle+D%22">Hoyle D</searchLink>; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.; Institute of Molecular Biotechnology (IMBA), Austrian Academy of Sciences, Vienna Biocenter, Campus Vienna Biocenter, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Martin+E%22">Martin E</searchLink>; Nestlé Research, Société des Produits Nestlé, Lausanne, Switzerland.; Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rae+J%22">Rae J</searchLink>; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Ferguson+C%22">Ferguson C</searchLink>; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Klinke+G%22">Klinke G</searchLink>; Metabolomics Core Technology Platform, Center for Organismal Studies (COS), Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Cielesh+M%22">Cielesh M</searchLink>; Charles Perkins Centre, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Macauslane+KL%22">Macauslane KL</searchLink>; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Larance+M%22">Larance M</searchLink>; Charles Perkins Centre, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Quadroni+M%22">Quadroni M</searchLink>; Protein Analysis Facility, University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Templeman+I%22">Templeman I</searchLink>; Centre for Nutrition, Exercise, and Metabolism, Department for Health, University of Bath, Bath, UK.<br /><searchLink fieldCode="AU" term="%22Walhin+JP%22">Walhin JP</searchLink>; Centre for Nutrition, Exercise, and Metabolism, Department for Health, University of Bath, Bath, UK.<br /><searchLink fieldCode="AU" term="%22Karagounis+LG%22">Karagounis LG</searchLink>; Nestlé Research, Société des Produits Nestlé, Lausanne, Switzerland.; Department of Diabetes, Endocrinology, Nutritional Metabolism, and Metabolism, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.; Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Betts+JA%22">Betts JA</searchLink>; Centre for Nutrition, Exercise, and Metabolism, Department for Health, University of Bath, Bath, UK.<br /><searchLink fieldCode="AU" term="%22Johnston+JD%22">Johnston JD</searchLink>; Section of Chronobiology, School of Biosciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.<br /><searchLink fieldCode="AU" term="%22Durussel+F%22">Durussel F</searchLink>; Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Firsov+D%22">Firsov D</searchLink>; Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Fournier+S%22">Fournier S</searchLink>; Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.; Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Müller+O%22">Müller O</searchLink>; Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.; Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schulz+BL%22">Schulz BL</searchLink>; School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Parton+RG%22">Parton RG</searchLink>; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia.; Centre for Microscopy and Microanalysis, The University of Queensland, St Lucia, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Weger+BD%22">Weger BD</searchLink>; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia. b.weger@uq.edu.au.; Nestlé Research, Société des Produits Nestlé, Lausanne, Switzerland. b.weger@uq.edu.au.<br /><searchLink fieldCode="AU" term="%22Gachon+F%22">Gachon F</searchLink>; Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia. frga@biomed.au.dk.; Nestlé Research, Société des Produits Nestlé, Lausanne, Switzerland. frga@biomed.au.dk.; Department of Biomedicine, Aarhus University, Aarhus, Denmark. frga@biomed.au.dk.; Steno Diabetes Center Aarhus, Aarhus, Denmark. frga@biomed.au.dk.
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  Data: <searchLink fieldCode="JN" term="%22101736592%22">Nature metabolism</searchLink> [Nat Metab] 2026 Feb; Vol. 8 (2), pp. 327-349. <i>Date of Electronic Publication: </i>2026 Feb 05.
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