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17.6% of patients in a German cohort with exocrine pancreatic cancer were diagnosed with a genetic tumor syndrome-a case for universal genetic testing?

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Title: 17.6% of patients in a German cohort with exocrine pancreatic cancer were diagnosed with a genetic tumor syndrome-a case for universal genetic testing?
Authors: William D; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg.; Core Unit for Molecular Tumor Diagnostics (CMTD), National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between German Cancer Research Center (DKFZ), Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden., Bermúdez M; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg., Kübler A; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg., Kahlert C; Department for Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology Dresden, Dresden., Distler M; Department for Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology Dresden, Dresden., Weitz J; Department for Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology Dresden, Dresden., Uhrig S; Computational Oncology Group (CO), Molecular Precision Oncology Program (MPOP), German Cancer Research Center (DKFZ), Heidelberg.; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg., Fröhlich M; Computational Oncology Group (CO), Molecular Precision Oncology Program (MPOP), German Cancer Research Center (DKFZ), Heidelberg.; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg., Hutter B; Computational Oncology Group (CO), Molecular Precision Oncology Program (MPOP), German Cancer Research Center (DKFZ), Heidelberg.; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg., Aust D; Institute of Pathology, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden., Baretton G; Institute of Pathology, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden., Wimberger P; Department of Gynecology and Obstetrics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden., Kast K; Department of Gynecology and Obstetrics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden., Meisel C; Department of Gynecology and Obstetrics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden., Gieldon L; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg., Porrmann J; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg., Wagner J; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg., Arlt M; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg., Franke M; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg., Fischer J; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg., Hackmann K; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg., Kreutzfeldt S; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg.; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg.; Institute of Human Genetics, Heidelberg University, Heidelberg., Mock A; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg.; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg.; Institute of Human Genetics, Heidelberg University, Heidelberg., Heilig CE; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg.; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg.; Institute of Human Genetics, Heidelberg University, Heidelberg., Lipka DB; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg.; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg.; Institute of Human Genetics, Heidelberg University, Heidelberg., Teleanu MV; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg.; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg.; Institute of Human Genetics, Heidelberg University, Heidelberg., Schlenk RF; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg.; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg.; Institute of Human Genetics, Heidelberg University, Heidelberg.; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg.; National Center of Tumor Diseases Trial Center, German Cancer Research Center and Heidelberg University Hospital, Heidelberg., Brors B; Computational Oncology Group, Molecular Precision Oncology Program, NCT Heidelberg and DKFZ, Heidelberg.; Division of Applied Bioinformatics, DKFZ, Heidelberg., Hübschmann D; Computational Oncology Group (CO), Molecular Precision Oncology Program (MPOP), German Cancer Research Center (DKFZ), Heidelberg.; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.; Pattern Recognition and Digital Medicine Group, Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg., Paramasivam N; Computational Oncology Group (CO), Molecular Precision Oncology Program (MPOP), German Cancer Research Center (DKFZ), Heidelberg.; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg., Richter D; Department of Translational Medical Oncology, National Center for Tumor Diseases (NCT), NCT Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; Center for Personalized Oncology, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden., Beck K; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg., Pfütze K; Sample Processing Laboratory, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg., Buchhalter I; Omics IT and Data Management Core Facility, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg., Weichert W; School of Medicine, Institute of Pathology, Technical University of Munich, Munich., Herold T; Department of Medicine III, University Hospital, Ludwig Maximilians University Munich, Munich.; Department of Hematology, Oncology, and Stem-Cell Transplantation, Munich Hospital Bogenhausen, Munich Municipal Hospital Group, Munich, Germany., Spiekermann K; Department of Medicine III, University Hospital, Ludwig Maximilians University Munich, Munich., Jost PJ; Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria., Keilholz U; Charité Comprehensive Cancer Center, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin.; German Cancer Consortium (DKTK), partner site Berlin, and German Cancer Research Center (DKFZ), Heidelberg., Klauschen F; Institute of Pathology, Ludwig Maximilian University of Munich, Munich.; BIFOLD-Berlin Institute for the Foundations of Learning and Data, Berlin., Bauer S; Department of Medical Oncology and Sarcoma Center, West German Cancer Center, University Duisburg-Essen, Medical School, Essen.; DKTK, Partner Site Essen, German Cancer Consortium (DKTK), Heidelberg., Siveke JT; DKTK, Partner Site Essen, German Cancer Consortium (DKTK), Heidelberg.; Bridge Institute of Experimental Tumor Therapy (BIT) and Division of Solid Tumor Translational Oncology (DKTK), West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen., Kindler T; University Cancer Center and Department of Internal Medicine III, University Medical Center Mainz, Mainz.; TRON-Translational Oncology, University Medical Center, Johannes Gutenberg University Mainz, Mainz.; DKTK, Partner Site Frankfurt/Mainz, a partnership between DKFZ and University Medical Center Mainz, Mainz., Boerries M; Institute of Medical Bioinformatics and Systems Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg.; German Cancer Consortium (DKTK), Partner Site Freiburg, a partnership between DKFZ and Medical Center-University of Freiburg, Freiburg., Illert AL; Department of Internal Medicine I, Division of Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Freiburg im Breisgau.; Department of Internal Medicine III, Klinikum Rechts der Isar, School of Medicine, Technical University of Munich, Munich., Bitzer M; Department of Internal Medicine I, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen., Schulze-Osthoff K; Department of Molecular Medicine, Interfaculty Institute for Biochemistry, Eberhard Karls University of Tübingen, Tübingen., Schirmacher P; Institute of Pathology, Heidelberg University Hospital, Heidelberg., Stenzinger A; Institute of Pathology, Heidelberg University Hospital, Heidelberg., Horak P; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg.; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg.; Institute of Human Genetics, Heidelberg University, Heidelberg., Heining C; Department of Translational Medical Oncology, National Center for Tumor Diseases (NCT), NCT Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; Center for Personalized Oncology, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden., Folprecht G; Department of Medicine I, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden, Germany., Fröhling S; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg.; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg.; Institute of Human Genetics, Heidelberg University, Heidelberg., Glimm H; Department of Translational Medical Oncology, National Center for Tumor Diseases (NCT), NCT Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; Center for Personalized Oncology, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden., Schröck E; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg.; Core Unit for Molecular Tumor Diagnostics (CMTD), National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between German Cancer Research Center (DKFZ), Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden., Jahn A; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg.; Center for Personalized Oncology, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.
Source: ESMO gastrointestinal oncology [ESMO Gastrointest Oncol] 2025 Aug 08; Vol. 9, pp. 100218. Date of Electronic Publication: 2025 Aug 08 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 9919053637606676 Publication Model: eCollection Cited Medium: Internet ISSN: 2949-8198 (Electronic) Linking ISSN: 29498198 NLM ISO Abbreviation: ESMO Gastrointest Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: 17.6% of patients in a German cohort with exocrine pancreatic cancer were diagnosed with a genetic tumor syndrome-a case for universal genetic testing?
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22William+D%22">William D</searchLink>; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg.; Core Unit for Molecular Tumor Diagnostics (CMTD), National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between German Cancer Research Center (DKFZ), Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.<br /><searchLink fieldCode="AU" term="%22Bermúdez+M%22">Bermúdez M</searchLink>; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg.<br /><searchLink fieldCode="AU" term="%22Kübler+A%22">Kübler A</searchLink>; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg.<br /><searchLink fieldCode="AU" term="%22Kahlert+C%22">Kahlert C</searchLink>; Department for Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology Dresden, Dresden.<br /><searchLink fieldCode="AU" term="%22Distler+M%22">Distler M</searchLink>; Department for Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology Dresden, Dresden.<br /><searchLink fieldCode="AU" term="%22Weitz+J%22">Weitz J</searchLink>; Department for Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology Dresden, Dresden.<br /><searchLink fieldCode="AU" term="%22Uhrig+S%22">Uhrig S</searchLink>; Computational Oncology Group (CO), Molecular Precision Oncology Program (MPOP), German Cancer Research Center (DKFZ), Heidelberg.; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.<br /><searchLink fieldCode="AU" term="%22Fröhlich+M%22">Fröhlich M</searchLink>; Computational Oncology Group (CO), Molecular Precision Oncology Program (MPOP), German Cancer Research Center (DKFZ), Heidelberg.; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.<br /><searchLink fieldCode="AU" term="%22Hutter+B%22">Hutter B</searchLink>; Computational Oncology Group (CO), Molecular Precision Oncology Program (MPOP), German Cancer Research Center (DKFZ), Heidelberg.; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.<br /><searchLink fieldCode="AU" term="%22Aust+D%22">Aust D</searchLink>; Institute of Pathology, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.<br /><searchLink fieldCode="AU" term="%22Baretton+G%22">Baretton G</searchLink>; Institute of Pathology, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.<br /><searchLink fieldCode="AU" term="%22Wimberger+P%22">Wimberger P</searchLink>; Department of Gynecology and Obstetrics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.<br /><searchLink fieldCode="AU" term="%22Kast+K%22">Kast K</searchLink>; Department of Gynecology and Obstetrics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.<br /><searchLink fieldCode="AU" term="%22Meisel+C%22">Meisel C</searchLink>; Department of Gynecology and Obstetrics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.<br /><searchLink fieldCode="AU" term="%22Gieldon+L%22">Gieldon L</searchLink>; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg.<br /><searchLink fieldCode="AU" term="%22Porrmann+J%22">Porrmann J</searchLink>; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg.<br /><searchLink fieldCode="AU" term="%22Wagner+J%22">Wagner J</searchLink>; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg.<br /><searchLink fieldCode="AU" term="%22Arlt+M%22">Arlt M</searchLink>; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg.<br /><searchLink fieldCode="AU" term="%22Franke+M%22">Franke M</searchLink>; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg.<br /><searchLink fieldCode="AU" term="%22Fischer+J%22">Fischer J</searchLink>; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg.<br /><searchLink fieldCode="AU" term="%22Hackmann+K%22">Hackmann K</searchLink>; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg.<br /><searchLink fieldCode="AU" term="%22Kreutzfeldt+S%22">Kreutzfeldt S</searchLink>; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg.; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg.; Institute of Human Genetics, Heidelberg University, Heidelberg.<br /><searchLink fieldCode="AU" term="%22Mock+A%22">Mock A</searchLink>; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg.; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg.; Institute of Human Genetics, Heidelberg University, Heidelberg.<br /><searchLink fieldCode="AU" term="%22Heilig+CE%22">Heilig CE</searchLink>; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg.; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg.; Institute of Human Genetics, Heidelberg University, Heidelberg.<br /><searchLink fieldCode="AU" term="%22Lipka+DB%22">Lipka DB</searchLink>; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg.; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg.; Institute of Human Genetics, Heidelberg University, Heidelberg.<br /><searchLink fieldCode="AU" term="%22Teleanu+MV%22">Teleanu MV</searchLink>; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg.; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg.; Institute of Human Genetics, Heidelberg University, Heidelberg.<br /><searchLink fieldCode="AU" term="%22Schlenk+RF%22">Schlenk RF</searchLink>; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg.; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg.; Institute of Human Genetics, Heidelberg University, Heidelberg.; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg.; National Center of Tumor Diseases Trial Center, German Cancer Research Center and Heidelberg University Hospital, Heidelberg.<br /><searchLink fieldCode="AU" term="%22Brors+B%22">Brors B</searchLink>; Computational Oncology Group, Molecular Precision Oncology Program, NCT Heidelberg and DKFZ, Heidelberg.; Division of Applied Bioinformatics, DKFZ, Heidelberg.<br /><searchLink fieldCode="AU" term="%22Hübschmann+D%22">Hübschmann D</searchLink>; Computational Oncology Group (CO), Molecular Precision Oncology Program (MPOP), German Cancer Research Center (DKFZ), Heidelberg.; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.; Pattern Recognition and Digital Medicine Group, Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg.<br /><searchLink fieldCode="AU" term="%22Paramasivam+N%22">Paramasivam N</searchLink>; Computational Oncology Group (CO), Molecular Precision Oncology Program (MPOP), German Cancer Research Center (DKFZ), Heidelberg.; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.<br /><searchLink fieldCode="AU" term="%22Richter+D%22">Richter D</searchLink>; Department of Translational Medical Oncology, National Center for Tumor Diseases (NCT), NCT Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; Center for Personalized Oncology, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.<br /><searchLink fieldCode="AU" term="%22Beck+K%22">Beck K</searchLink>; Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg.<br /><searchLink fieldCode="AU" term="%22Pfütze+K%22">Pfütze K</searchLink>; Sample Processing Laboratory, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg.<br /><searchLink fieldCode="AU" term="%22Buchhalter+I%22">Buchhalter I</searchLink>; Omics IT and Data Management Core Facility, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg.<br /><searchLink fieldCode="AU" term="%22Weichert+W%22">Weichert W</searchLink>; School of Medicine, Institute of Pathology, Technical University of Munich, Munich.<br /><searchLink fieldCode="AU" term="%22Herold+T%22">Herold T</searchLink>; Department of Medicine III, University Hospital, Ludwig Maximilians University Munich, Munich.; Department of Hematology, Oncology, and Stem-Cell Transplantation, Munich Hospital Bogenhausen, Munich Municipal Hospital Group, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Spiekermann+K%22">Spiekermann K</searchLink>; Department of Medicine III, University Hospital, Ludwig Maximilians University Munich, Munich.<br /><searchLink fieldCode="AU" term="%22Jost+PJ%22">Jost PJ</searchLink>; Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Keilholz+U%22">Keilholz U</searchLink>; Charité Comprehensive Cancer Center, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin.; German Cancer Consortium (DKTK), partner site Berlin, and German Cancer Research Center (DKFZ), Heidelberg.<br /><searchLink fieldCode="AU" term="%22Klauschen+F%22">Klauschen F</searchLink>; Institute of Pathology, Ludwig Maximilian University of Munich, Munich.; BIFOLD-Berlin Institute for the Foundations of Learning and Data, Berlin.<br /><searchLink fieldCode="AU" term="%22Bauer+S%22">Bauer S</searchLink>; Department of Medical Oncology and Sarcoma Center, West German Cancer Center, University Duisburg-Essen, Medical School, Essen.; DKTK, Partner Site Essen, German Cancer Consortium (DKTK), Heidelberg.<br /><searchLink fieldCode="AU" term="%22Siveke+JT%22">Siveke JT</searchLink>; DKTK, Partner Site Essen, German Cancer Consortium (DKTK), Heidelberg.; Bridge Institute of Experimental Tumor Therapy (BIT) and Division of Solid Tumor Translational Oncology (DKTK), West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen.<br /><searchLink fieldCode="AU" term="%22Kindler+T%22">Kindler T</searchLink>; University Cancer Center and Department of Internal Medicine III, University Medical Center Mainz, Mainz.; TRON-Translational Oncology, University Medical Center, Johannes Gutenberg University Mainz, Mainz.; DKTK, Partner Site Frankfurt/Mainz, a partnership between DKFZ and University Medical Center Mainz, Mainz.<br /><searchLink fieldCode="AU" term="%22Boerries+M%22">Boerries M</searchLink>; Institute of Medical Bioinformatics and Systems Medicine, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg.; German Cancer Consortium (DKTK), Partner Site Freiburg, a partnership between DKFZ and Medical Center-University of Freiburg, Freiburg.<br /><searchLink fieldCode="AU" term="%22Illert+AL%22">Illert AL</searchLink>; Department of Internal Medicine I, Division of Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Freiburg im Breisgau.; Department of Internal Medicine III, Klinikum Rechts der Isar, School of Medicine, Technical University of Munich, Munich.<br /><searchLink fieldCode="AU" term="%22Bitzer+M%22">Bitzer M</searchLink>; Department of Internal Medicine I, University Hospital Tübingen, Eberhard Karls University of Tübingen, Tübingen.<br /><searchLink fieldCode="AU" term="%22Schulze-Osthoff+K%22">Schulze-Osthoff K</searchLink>; Department of Molecular Medicine, Interfaculty Institute for Biochemistry, Eberhard Karls University of Tübingen, Tübingen.<br /><searchLink fieldCode="AU" term="%22Schirmacher+P%22">Schirmacher P</searchLink>; Institute of Pathology, Heidelberg University Hospital, Heidelberg.<br /><searchLink fieldCode="AU" term="%22Stenzinger+A%22">Stenzinger A</searchLink>; Institute of Pathology, Heidelberg University Hospital, Heidelberg.<br /><searchLink fieldCode="AU" term="%22Horak+P%22">Horak P</searchLink>; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg.; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg.; Institute of Human Genetics, Heidelberg University, Heidelberg.<br /><searchLink fieldCode="AU" term="%22Heining+C%22">Heining C</searchLink>; Department of Translational Medical Oncology, National Center for Tumor Diseases (NCT), NCT Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; Center for Personalized Oncology, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.<br /><searchLink fieldCode="AU" term="%22Folprecht+G%22">Folprecht G</searchLink>; Department of Medicine I, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Fröhling+S%22">Fröhling S</searchLink>; National Center for Tumor Diseases (NCT), NCT Heidelberg, a partnership between DKFZ and Heidelberg University Hospital, Heidelberg.; Division of Translational Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg.; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg.; Institute of Human Genetics, Heidelberg University, Heidelberg.<br /><searchLink fieldCode="AU" term="%22Glimm+H%22">Glimm H</searchLink>; Department of Translational Medical Oncology, National Center for Tumor Diseases (NCT), NCT Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; Center for Personalized Oncology, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.<br /><searchLink fieldCode="AU" term="%22Schröck+E%22">Schröck E</searchLink>; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg.; Core Unit for Molecular Tumor Diagnostics (CMTD), National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between German Cancer Research Center (DKFZ), Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.<br /><searchLink fieldCode="AU" term="%22Jahn+A%22">Jahn A</searchLink>; Institute for Clinical Genetics, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.; ERN GENTURIS, Hereditary Cancer Syndrome Center Dresden, Dresden.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden.; German Cancer Consortium (DKTK), Dresden.; German Cancer Research Center (DKFZ), Heidelberg.; Center for Personalized Oncology, University Hospital Carl Gustav Carus at TUD Dresden University of Technology and Faculty of Medicine of TUD Dresden University of Technology, Dresden.
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  Data: <searchLink fieldCode="JN" term="%229919053637606676%22">ESMO gastrointestinal oncology</searchLink> [ESMO Gastrointest Oncol] 2025 Aug 08; Vol. 9, pp. 100218. <i>Date of Electronic Publication: </i>2025 Aug 08 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Ltd%22">Elsevier Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9919053637606676 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2949-8198 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2229498198%22">29498198 </searchLink><i>NLM ISO Abbreviation: </i>ESMO Gastrointest Oncol <i>Subsets: </i>PubMed not MEDLINE
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      – TitleFull: 17.6% of patients in a German cohort with exocrine pancreatic cancer were diagnosed with a genetic tumor syndrome-a case for universal genetic testing?
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